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Xenical works by keeping your intestines from absorbing some of the fats from the food that you eat. The undigested fat goes out of your body in your bowel movements. This medicine is available both over-the-counter (OTC) and with your doctor's prescription.

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Also known as: Orlistat


Xenical (orlistat) blocks some of the fat that you eat, keeping it from being absorbed by your body.

Xenical is used to aid in weight loss, or to help reduce the risk of regaining weight already lost. This medicine must be used together with a reduced-calorie diet and is to used only by adults.

Xenical is the prescription-strength form of orlistat. The alli brand of orlistat is available without a prescription.


Usual Adult Dose for Obesity:

120 mg orally three times a day with each main meal containing fat. The dose may be taken during the meal or within 1 hour of completing the meal.

Usual Pediatric Dose for Obesity:

12 years or older: 120 mg orally three times a day with each main meal containing fat. The dose may be taken during the meal or within 1 hour of completing the meal.

Detailed Xenical dosage information


If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Xenical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Xenical if you are allergic to orlistat, or if you have malabsorption syndrome (an inability to absorb food and nutrients properly).

You also should not use this medicine if you have:

gallbladder problems; or if you are pregnant.

Do not use alli if:

you are not overweight; you have had an organ transplant; or you use cyclosporine (to prevent organ transplant rejection).

To make sure Xenical is safe for you, tell your doctor if you have ever had:

kidney stones; gallbladder disease; pancreatitis; underactive thyroid; liver disease; kidney disease; or an eating disorder (anorexia or bulimia).

Do not use Xenical if you are pregnant. Weight loss is not recommended during pregnancy, even if you are overweight. Stop taking orlistat and tell your doctor right away if you become pregnant.

Taking orlistat can make it harder for your body to absorb certain vitamins. These vitamins are important if you are nursing a baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Xenical is not approved for use by anyone younger than 12 years old. Do not give alli to anyone under 18 years old.

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