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Provigil (Modafinil)
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Provigil

Provigil is used to treat excessive sleepiness caused by certain sleep disorders. This includes narcolepsy, sleep apnea, and shift work sleep disorder. Provigil can be taken every day depending on the condition for which this medication is being used for.

Other names for this medication:
Alertec, Carim, Dekast, Modafinil, Modafinilo, Modalert, Modapro, Modatec, Modavigil, Modfil, Modiodal, Provake, Renea, Vigia

Similar Products:
Effexor, Levlen, Viramune, Aldara, Imodium, Vantin, Chloromycetin

Also known as: Modafinil

Description

Provigil is prescribed for people who suffer from sleep disorders or narcolepsy - a pathological sleepiness associated with brain disorders. The active component of Provigil is Modafinil. Researches have shown numerous advantages of using Modafinil as a stimulator in comparison with amphetamines. Provigil doesn't cause addiction syndrome, it almost does not cause euphoria, reduces the peripheral nervous system tension and has very small effect on blood pressure.

Dosage

The Provigil dosage your doctor prescribes will depend on several factors. These include:

  • the type and severity of the condition you’re using Provigil to treat
  • your age
  • other medical conditions you may have
Typically, your doctor will start you on a low dosage and adjust it over time to reach the dosage that’s right for you. They’ll ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.

Dosage for narcolepsy and sleep apnea

For daytime sleepiness caused by narcolepsy or obstructive sleep apnea, the typical dosage is 200 mg once a day in the morning. Higher doses are sometimes used, up to 400 mg daily. However, these doses may not be any more effective than 200 mg daily.

Dosage for shift work sleep disorder

For excessive sleepiness due to shift work sleep disorder, the typical dosage is 200 mg taken about one hour before the start of your work shift.

Dosage for people with liver problems

If you have severe liver problems, your doctor will likely prescribe a lower dosage. The recommended dosage for people with this condition is typically 100 mg daily.

Dosage for seniors

Seniors may be more sensitive to the effects of Provigil, especially side effects. If you’re over 65 years of age, your doctor may prescribe a lower dosage.

What if I miss a dose?

If you miss a dose, take it as soon as you remember. Remember that Provigil will keep you awake, so don’t take it unless you plan to be awake for several hours. If it’s close to your bedtime, skip the missed dose and take it the next day at the normal time.

Never try to catch up by taking two doses at a time. This can cause dangerous side effects.

Will I need to use this drug long-term?

Yes, Provigil is usually taken long-term by people with narcolepsy or sleep apnea. These are chronic conditions that often require long-term treatment to improve symptoms of daytime sleepiness.

Overdose

If you overdose Provigil and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Provigil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Provigil if you have ever had an allergic reaction or skin rash while taking modafinil or armodafinil (Nuvigil).

To make sure Provigil is safe for you, tell your doctor if you have:

angina (chest pain); cirrhosis or other liver problem; kidney disease; high blood pressure, heart disease, or history of heart attack; a history of mental illness or psychosis; or history of alcoholism or drug addiction.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Provigil can make certain birth control less effective. Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment. Talk with your doctor about the best methods of birth control to use while taking Provigil.

It is not known whether modafinil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Provigil is not approved for use by anyone younger than 17 years old.

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The luteinizing hormone-releasing hormone (LHRH) system of the platyfish Xiphophorus has been studied using immunohistochemistry and retrograde transport of horseradish peroxidase (HRP). In tissue level turnover of bone cells, bone remodeling shows a sequential events of activation, resorption, reversal and formation. To evaluate and improve adherence to American Diabetes Association guidelines for prophylactic aspirin therapy in ambulatory patients with diabetes using a pharmacy-directed intervention. Questionnaire research with two measurements among Dutch general practitioners, practice nurses and physiotherapists participating in a pilot study. A linear model analysis confirmed these findings while adjusting for potential confounders. Noneligible Donors as a Strategy to Decrease the Organ Shortage. Quality control between the two laboratories was assessed during the testing.

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Reinventing the community hospital: a retrospective population-based cohort study of a natural experiment using register data. We end by discussing how cross talk between barrier epithelial and endothelial cells, perivascular cells, and basement membrane signaling contribute to generate and maintain organ-blood barriers. While all three variants were structurally similar to the wild type, only T80S was functionally similar. There was a tendency of lower levels of Uromodulin values in fetuses with severe renal impairment prenatally. Longitudinal patterns of lung function differ between asthmatics, but these phenotypes have not been assessed for heritability or predictive ability. Barbiturate effects on EEG abnormality in complex partial epilepsy. These findings suggest a potential role for known mediators of bone homeostasis in the pathogenesis of HF and possibly represents new targets for therapeutic intervention in this disorder. After an additional 6 weeks of observation, surgery was performed due to the absence of any clinical and electrodiagnostic evidence of recovery. Moreover, in contrast to previous studies, our data also demonstrate that complete regression and prevention of LVH in HD patients is possible.

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Glutathione transferase (GST) (EC 2.5.1.18) was purified from a cell extract of Issatchenkia orientalis, and two GST isoenzymes were isolated. Off-pump connection of the pulmonary veins with bipolar radiofrequency: toward a complete epicardial ablation. Action of respiratory vagal reflexes on different inspiratory muscles. The epithelial component is generally positive for CK7, TTF-1, Napsin A. Aneurysmal bone cyst of the thoracic spine: treatment by excision and segmental stabilization with Luque rods. The study aims to provide paediatricians in Western Australia (WA) with educational resources (http://www.ichr.uwa.edu.au/alcoholandpregnancy) about the prevention of prenatal alcohol exposure and fetal alcohol spectrum disorder, and assess changes in their knowledge, attitudes and practice about fetal alcohol syndrome (FAS) and alcohol consumption in pregnancy. To explore the influencing factors of establishing diabetes mellitus animal model by the combination of feeding high-fat diet for different periods of time and different dosage of streptozotocin (STZ).

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Clinical peculiarities of the first depressive episodes in adolescents. We investigate the forces between emulsion droplets in the presence of neutral polymer-surfactant complexes. Indeed, ionizing radiation-induced BRCA1 foci assembly was repressed when Bcl-2 was expressed ectopically, in human SV40 fibroblasts, or spontaneously, in lymphoma t(14:18) cells and in HeLa and H460 cancer cell lines. Hospital confrontation: a cry for help and technique for change. We have monitored the lateral diffusion of lipid probes, DiIC(18)(3) and FAST DiI which are similar in their intrinsic fluorescence properties but differ in their structure, in native and cholesterol-depleted hippocampal membranes using the fluorescence recovery after photobleaching (FRAP) approach. The 60,000-molecular-weight cysteine-rich outer membrane protein (OMP2) from Chlamydia trachomatis participates in the disulfide-mediated outer-membrane organization unique to this organism. It is imperative that such studies are reported with transparency allowing the detection of any potential bias that may invalidate the results. In contrast, although the frequency was not higher than the general population, all carriers of both mutations among short distance runners and swimmers were of lipitor reviews 2020 elite competitive caliber. However, like cardiothoracic surgery, they were among the most equitably distributed compared with other specialties. Heavy metals removal using hydrogel-supported nanosized hydrous ferric oxide: Synthesis, characterization, and mechanism.

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Linear parabolic single-crystal diamond refractive lenses for synchrotron X-ray sources. The evaluation of contribution of motor transport exhaust to the integral characteristics of a risk of environmental air pollution. The most frequently encountered tumor, the rhabdomyoma, is associated with tuberous sclerosis. To study prospectively the effects of propofol anesthesia on seizure control, hemodynamics and course of intensive care in patients with refractory status epilepticus. Cellular localization of thiol-proteinase inhibitor in the epidermis of the newborn rat. Blood clearances of contrast material in patients with impaired renal function. Deep burns induced a more profound initial increase in tissue histamine concentration than the partial thickness and superficial burns. In addition, they were asked when and where they were hospitalized for myocardial infarction, stroke, surgical procedures, and for other conditions and procedures. As a minor product, an activated prorenin having an isoelectric point of 5.2 was also produced.

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