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Prograf (Tacrolimus)

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Prograf is in a class of medications called immunosupressants. It works by decreasing the activity of the immune system to prevent it from attacking the transplanted organ.

Other names for this medication:
Acroli, Crolim, Cromus, Mustopic, Olmis, Pangraf, Protopic, Seegraf, Tacloran, Tacrel, Tacrim, Tacroderm, Tacrograf, Tacrokid, Tacrolimus, Tacromus, Tacrotor, Tacrovate, Tacroz, Tacstead, Talimus, Tarcel, Techlomus, Topgraf, Triplibact, Vingraf

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Also known as: Tacrolimus


Generic Prograf target is to prevent rejection of kidney, heart, liver transplants. It can be used together with other medicines. The effectiveness of Generic Prograf is in decreasing immune system of the body. Prograf is also known as Tacrolimus, Fujimycin, Advagraf, Protopic. Generic name of Generic Prograf is Tacrolimus. Brand names of Generic Prograf are Prograf, FK 506.


Take Prograf exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

You may receive an injection of Prograf shortly after your transplant. The injection is given until you are ready to take the pill form of tacrolimus.

Take Prograf at the same time each day, with a full glass of water.

Swallow the capsule whole and do not crush, chew, break, or open it.

Mix Prograf oral granules with water right before you take them. Do not save this mixture for later use. Do not get the powder or mixture on your skin or in your eyes. If this happens, wash your skin with soap and water or rinse your eyes with water.

You may take Prograf with or without food, but take it the same way each time.

Your dose needs may change if you switch to a different brand, strength, or form of this medicine. All forms of tacrolimus are not equivalent and may not have the same dose or schedule. Avoid medication errors by using only the form and strength your doctor prescribes.

You will need frequent medical tests, and your blood pressure will need to be checked often.

Store at room temperature away from moisture and heat.

Detailed Prograf dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Prograf are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Prograf if you are allergic to tacrolimus or hydrogenated castor oil, or if you have used cyclosporine (Neoral, Sandimmune, Gengraf) within the past 24 hours.

Using Prograf may increase your risk of developing serious infections or certain types of cancer, such as lymphoma or skin cancer. Your risk may be higher if you are treated over long periods of time with drugs that weaken the immune system. Ask your doctor about this risk and about symptoms to watch for.

Some people taking Prograf after a kidney transplant have developed diabetes. This effect has been seen most commonly in people who are Hispanic or African-American.

To make sure Prograf is safe for you, tell your doctor if you have::

problems with your liver, kidney, or heart that are not related to your transplant; long QT syndrome (in you or a family member); or if you are scheduled to receive a vaccine;

Tell your doctor if you plan to get pregnant. Tacrolimus may harm an unborn baby, and can worsen conditions such as diabetes or high blood pressure in the mother. Use effective birth control before and during treatment with Prograf.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of tacrolimus on the baby.

If you are a man, use birth control before and during treatment with Prograf if your sex partner is able to get pregnant.

Pregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.

Ask a doctor if it is safe to breastfeed while using this medicine.

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Relationship of Transportation Noise and Annoyance for Two Metropolitan Cities in Korea: Population Based Study. Neurotrophins acting through high-affinity tyrosine kinase receptors (trkA, trkB, and trkC) play a crucial role in regulating survival and maintenance of specific neuronal functions after injury. Two cases of histologically verified intramedullary cavernous angiomas at C3 and D5-6 are presented. Blood was collected from 39 RA patients and 31 healthy controls. The results showed that only Ad- hTERT had high infection efficiency and produced a positive polyclone population (hTERT-bMGEs).


The optomechanical parameters involved with this technique require great technological skill and should be placed in experienced hands. The cellular chaperone heat shock protein 90 facilitates Flock House virus RNA replication in Drosophila cells. The importance of providing good perioperative analgesia requires us to have an in-depth understanding of the characteristics of such pain, the therapeutic armamentarium available and the technique to be used. Subcutaneous mastectomy for central tumors of the breast, with immediate reconstruction. An ethnographic study in rural Zimbabwe, where approximately one third of adults are infected, revealed how stigma, suffering, shame, and silence are mutually supporting concepts that challenge health promotion efforts. Analysis by multiple regression with neonatal ponderal index as the primary dependent variable revealed a significant correlation between lowered ponderal index and decreased urinary urea and ammonia. Effect of dopamine D3 receptor blockade on renal function and glomerular size in diabetic rats. However, differences between dry and operational weight, and the consequent size of necessary foundation structures are likely to limit opportunities for reducing overall burden profiles through material substitution. HIC resolution of an IgG1 with an oxidized Trp in a complementarity determining region. The dominant transmission of optic disc drusen, mottled fundus, and angioid streaks in this family is not due to alterations in the ABCC6 gene.

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Discontinuation of any TT drug did not increase the thromboembolic event rate, while it was associated with reduced risk of major bleeding. Chronic exposure to H2S in geothermal areas was associated with increases in nervous system and respiratory diseases. While surgery provides modest disease-free survival, most patients should be offered immunotherapy, particularly those with advanced stage, grade, nodal involvement or metastases. Subsequently, it was discovered that high response rates could be maintained solely through presentation of shocks that were not affected by responses. A previously perceived problem of centerband aliasing in TOP can be eliminated with an algorithm that uses larger subspectral albenza cost widths and the sideband order dimension to distinguish centerbands from sidebands. Sociodemographic profile of medicines users in Brazil: results from the 2014 PNAUM survey. The sequence upstream of the CP49 gene possesses promoter activity and is able to drive lens-preferred expression in both transfection and transgenic experiments. We conclude that the AAS 17alpha-meT modulates distinct anxiety domains in females through a fast-acting mechanism. Two cases of spondylodiskitis due to Candida albicans were diagnosed: a 29 year old man and a 35 year old woman.

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On the basis of N-hydroxylation, the VH/VD and (V/K)H/(V/K)D ratios are 0.8-0.9. Rarely, labial fusion arises secondary to maternal androgen ingestion or an androgen-secreting tumor during pregnancy. Dependence of the structure of malate dehydrogenase on the type of metabolism in fresh water filamentous colorless sulfur bacteria of the Beggiatoa species. 1st segment net and gross cumulative pregnancy rates were 0. amoxil suspension dosage 7 and 1.2/100 respectively, at 3.5 years. A healthy 20-year-old woman with myopia had uneventful bilateral laser in situ keratomileusis after which the uncorrected visual acuity was 20/20 in the right eye and 20/30 in the left eye. Neuropsychological alterations and neuroradiological findings in patients with post-traumatic concussion: Results of a pilot study. Facilitators to PA comprised exercising with peers and skilled instructors. A 2-month, prospective, observational study to investigate the incidence and spread of MSSA in the surgical ICU of UMCU and historical data collected during a 10-year period regarding MRSA.

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This study highlights how the practices of family medicine residency graduates may change over time. Macromolecules like insulin, leptin and transferrin may cross the BBB via receptor mediated transcytosis. We assessed the proportion of patients treated with either simvastatin 20 or 40 mg or atorvastatin 80 mg who achieved low-density lipoprotein cholesterol (LDL-C) goals of 2.5 or 2.0 mmol/l in the Incremental Decrease in End Points Through Aggressive Lipid Lowering (IDEAL) study. Health-related quality of life in Brazilian community-dwelling and institutionalized elderly: Comparison between genders. P 300 --an orienting reaction in the human auditory evoked response.

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The present study investigated if unconscious primes can be processed according to different stimulus-response (S-R) rules simultaneously. We assessed the hypothesis that global and regional left atrial (LA) function is altered in patients with chronic primary mitral regurgitation (MR) secondary to myxomatous mitral valve disease (MMVD). Some factors related to architectural creativity in graduating architecture students. In the last few years, several strategies have been evaluated to improve the long-term effect of lifestyle modification. This study also tested for an interaction between the drugs and alcohol on the eighth day. Apolipoprotein E (apoE) is a 299 amino acid protein that has been demonstrated to modify functional recovery following acute ischemic and traumatic brain injury. The Photochemical Branching Ratio in 1,6-Dinitropyrene Depends on the Excitation Energy. The aim of the study was to examine the effects of taurine on hepatic fibrogenesis and in isolated hepatic stellate cells (HSC). The results should be extrapolated to treatment in humans with caution. We investigated whether macrophage infiltration in the conjunctiva in this EC model is inhibited by clodronate liposomes (CL2MDP-lip).

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Allometric analysis of chondrocranial growth seeks to provide objective measures of morphogenetic form change during ontogeny of the primordial skull. We also document that cyclosporin recovers the low concentration of intracellular multidrugs in lymphocytes by competitively binding to P-glycoprotein, a product of multidrug resistance gene-1, in vitro. We studied the eye movements and visual perception in a man with extensive bilateral occipital lesions acquired at birth. The focus of this article is to review some recent advances in our understanding of mechanisms specific to the regulation of inducible mPGES-1 in inflammatory arthritis. Probabilistic Assessment of Above Zone Pressure Predictions at a Geologic Carbon Storage Site. specific polymorphisms of genes regulating intracellular redox balance and oxidative stress are related to atherogenesis. A Screening Test for Heterophile Antibodies in Infectious Mononucleosis. To address this possibility, Saccharomyces cerevisiae strains lacking either pol zeta (rev7), pol eta (rad30), or both were tested for trinucleotide repeat (TNR) contractions using three separate, sensitive genetic assays. The biological and behavioral link between HIV and STDs is so close that the same strategies are important can i take 2 claritin pills a day for prevention of both. This review focuses on detection methods commonly used in cell-based microfluidic systems, and provides a general survey and an in-depth look at recent developments in optical and electrochemical detection methods for microfluidic applications for biological systems, particularly cell analysis.

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