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Prilosec (Omeprazole)

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Prilosec is used alone or with other medications to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus in adults and children.

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Also known as: Omeprazole


Prilosec (omeprazole) is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

Prilosec is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach acid. Omeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Prilosec may also be given together with antibiotics to treat gastric ulcer caused by infection with Helicobacter pylori (H. pylori).

Over-the-counter Prilosec OTC is used in adults to help control heartburn that occurs 2 or more days per week. Prilosec OTC must be taken as a course for 14 days in a row.


Generic Prilosec OTC is available in tablets (10 mg, 20 mg, 40 mg) and capsules. You should take Generic Prilosec OTC every day for 14 days. Do not take Generic Prilosec OTC more than one pill a day. Take Generic Prilosec OTC before eating. Do not break, crush or open a delayed-release capsule. Your symptoms may get better before the condition is completely treated. Take Generic Prilosec OTC with water. If you want to achieve most effective results do not stop taking Generic Prilosec OTC suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Prilosec are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel sweaty or light-headed.

You should not use Prilosec if you are allergic to omeprazole, or if:

you are also allergic to medicines like omeprazole, such as esomeprazole, lansoprazole, pantoprazole, rabeprazole, Nexium, Prevacid, Protonix, and others; you had breathing problems, kidney problems, or a severe allergic reaction after taking omeprazole in the past; or you also take HIV medication that contains rilpivirine (such as Complera, Edurant, Odefsey, Juluca).

Ask a doctor or pharmacist if this medicine is safe to use if you have:

trouble or pain with swallowing; bloody or black stools, vomit that looks like blood or coffee grounds; heartburn that has lasted for over 3 months; frequent chest pain, heartburn with wheezing; unexplained weight loss; nausea or vomiting, stomach pain; liver disease; low levels of magnesium in your blood; or osteoporosis or low bone mineral density (osteopenia).

You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Do not give Prilosec to a child without medical advice.

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The etiology and clinical characteristics of acute lower gastrointestinal bleeding in patients hospitalized for comorbid illnesses. In particular, HDAC4, 5, 7 and 9 belong to the subclass IIa and share many transcriptional partners, including members of the MEF2 family. Role of the B domain in proteolytic inactivation of activated coagulation factor VIII by activated protein C and activated factor X. Comparative evaluation of the surgical treatment of acute appendicitis: open appendicetomy versus laparoscopic appendicectomy in the national hospital hospital Carlos a. Using the computational probabilistic model of the apoptotic pathway, verified by experimental results from human leukemia and lymphoma cell lines, we show that inhibition of XIAP has a non-linear effect on sensitization towards apoptosis induced by the BH3 mimetic HA14-1. Here, the spectral element method is examined because the high-order approximation provides greater flexibility in resolving multiple length scales. Response to methotrexate predicts long-term mortality of patients with rheumatoid arthritis independent of the degree of response: results of a re-evaluation 30 years after baseline. DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma. Phosphatidylinositol 3,4,5-trisphosphate modulation in SHIP2-deficient mouse embryonic fibroblasts.

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