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Mebrin (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Mebrin, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Mebrin is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alcalm, Alcicalm, Alfresh, Alpam, Alpaz, Alprac, Alpradol, Alpram, Alpranex, Alprasert, Alprocontin, Alprowon, Alsert, Alzac, Alzoact, Alzocum, Alzonex, Alzopax, Alzorix, Ambusyn, Anxicalm, Anzocalm, Aryalam, Benzax, Berest, Coolam, Cooltime, Deproz, Depsolam, Faxtin, Fluzolam, Golprax, Indolam, Notens, Pacyl, Paxor, Plaxid, Pyrex, Restyl, Romipraz, Selamb, Silam, Somnirest, Suzilam, Tagat, Tenzorid, Ziety, Zolax, Zolipax, Zolorel

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Also known as: Alprazolam


Xanax (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

Xanax is used to treat anxiety disorders and anxiety caused by depression.

Xanax is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase Xanax on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Mebrin with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Mebrin. Ask your doctor how to avoid withdrawal symptoms when you stop using Mebrin.

Keep track of the amount of medicine used from each new bottle. Mebrin is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Xanax XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Xanax XR dosage information

Side effects

The most common side effects associated with Mebrin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Xanax if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Xanax is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Xanax while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Xanax is not approved for use by anyone younger than 18 years old.

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Manganese accumulation was fourfold to fivefold higher in brains of Zip14 KO mice compared with young adult wild-type mice. Recent advances in ultrasonic and neuroimaging coupled with stereotactic techniques and improvements in cryosurgical instrumentation may prove useful in the future percutaneous destruction of selective intracranial neoplasms. In this work, rat BMSCs were infected by recombinant lentiviruses to construct tropomyosin receptor kinase A (TrkA)-overexpressing BMSCs and TrkA-shRNA-expressing BMSCs, which were then used in transplantation for rat sciatic nerve defects. Hepatic perivascular epithelioid cell tumor treated by transarterial embolization plus radiofrequency ablation: A case report and literature review. This app can improve information sharing for children and young people with a diagnosis of autism, or those undergoing an autism assessment.

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Phenotyping of VIGS-mediated gene silencing in rice using a vector derived from a DNA virus. The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements. Novice PAs sharing the self-reliant perspective experienced environmental obstacles-but few, if any, individual obstacles-to transfer of learning. In Utero Oxcarbazepine Exposure and Neonatal Abstinence Syndrome: Case Report and Brief Review of the Literature. The latency-corrected geometric root-mean squared error was below 0.75 mm (2D US) and below 1.75 mm (3D US). Additionally, superoxide production was significantly increased in plavix dosage chart the microvessels of the ZDFO group.

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Mycophenolate mofetil as induction therapy after liver transplantation. In the present study, it was identified that BBR remarkably attenuated H2O2-induced apoptotic cell death via quenching ROS production and increasing SOD activity. FUNGI ON MEDICINAL AND AROMATIC PLANTS IN THE NORTH WEST HIMALAYAS. The epidemiology of Staphylococcus aureus carriage in patients attending inner city sexually transmitted infections and community clinics in Calgary, Canada. Binding of antibacterial magainin peptides to electrically neutral membranes: thermodynamics and structure.

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This survey shows that there are many drugs that in addition to surgery might influence the natural course of clinical PVR during different stages. Management of four pregnant women with multidrug-resistant tuberculosis. The sensitivity of these 1-h immunoassay procedures for the determination of human prolactin was 2 ng/ml. Urine cadmium levels and albuminuria in a general population from Spain: A floxin tablets gene-environment interaction analysis. A short atrioventricular interval is associated with a greater mean BP decrease at the onset of tachycardia.

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Long-term impact of sewage sludge application on soil microbial biomass: An evaluation using meta-analysis. Both indices are derived from administrative databases and can efficiently capture comorbidity among large patient populations. In each case, we assessed tuberous sclerosis complex-associated symptoms, the treatment effect and adverse events. Four pain-assessment methods were used and an assessment of the technical ease of venepuncture was made. In vivo genotoxicity of nitrates and nitrites in germ cells of male mice. A comparison of blind nasotracheal and succinylcholine-assisted intubation in the poisoned patient. The broad end of the microfilament bundle is anchored to the macrocilium by striated rootlet fibers that extend from the basal bodies into the bundle and are linked to the microfilaments by periodic bridges. Skeletal muscle function has been scarcely investigated in sickle cell disease (SCD) so that the corresponding impact of sickle hemoglobin is still a matter of debate.

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Habitual intake of anthocyanins and flavanones and risk of cardiovascular disease in men. Multistrip Western blotting to increase quantitative data output. Single amino acid change in the helicase domain of the putative RNA replicase of turnip crinkle virus alters symptom intensification by virulent satellites. Forensic odontology plays important role in identification of human remains in mass disasters such as air crash, tsunami, and accidents. To establish management protocol for mandibular angle fracture, we describe pertinent factors including cause, impacted third molar and recent treatment tendency. After cytogenetic detection and confirmation by fluorescence-in-situ hybridization we performed short tandem repeat typing in a child with i(9p), three with i(12p) and three with i(18p). However, their biocompatibility and high potency does not negate the existence of challenges resulting from physicochemical properties of proteins and peptides, including large size, short half-life, capability to provoke immune responses and susceptibility to degradation. Sterilization by minilaparotomy may be done 48 hours after delivery. High 2,3-DPG blood cardioplegia and myocardial preservation during cardiopulmonary bypass.

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