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Ilosone (Erythromycin)
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Ilosone

Ilosone belongs to a group of drugs called macrolide antibiotics. These work by killing or stopping the growth of the bacteria that cause infections.

Other names for this medication:
Cynopryl, Eltocin, Erypal, Erythrocin, Erythrokem, Erythromycin, Estocin, Pediazole

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Also known as: Erythromycin

Description

Generic Ilosone is created by pharmacy specialists to struggle against infections (pneumonia, Legionnaire's disease, sexually transmitted diseases, skin infections). It is also helpful in treatment of severe acne and prevention of heart diseases in people who suffer from rheumatic fever. Target of Generic Ilosone is to control, ward off and terminate bacteria. Generic Ilosone acts as an anti-infection remedy. Generic Ilosone operates by killing bacteria which spreads by infection. Ilosone is also known as Erythromycin. Generic Ilosone and other antibiotics don't treat viral infections (flu, cold and other). Generic Ilosone is a macrolide antibiotic. Generic name of Generic Ilosone is Erythromycin. Brand names of Generic Ilosone are Ilosone, MY-E, Erythrocin Stearate Filmtab, E-Mycin, Ery-Tab, E.E.S.-200, Robimycin, E.E.S.-400, Eryc, EryPed, Erythrocot, CE Dispertab.

Dosage

This section provides information on the proper use of a number of products that contain erythromycin. It may not be specific to Ilosone. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Take this medicine with or without food. PCE® tablets may be taken without meals or at least 30 minutes to 2 hours before meals.

Measure the mixed oral liquid with a marked measuring spoon, oral syringe, or medicine cup.

Keep using the medicine for the full time of treatment, even if you or your child begin to feel better after the first few doses. Your infection may not go away if you stop using the medicine too soon.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (granules for suspension, suspension, and tablets): For treatment of bacterial infections: Adults—400 milligrams (mg) every 6 hours or 800 mg every 12 hours. Depending on the severity of your infection, your doctor may increase your dose as needed up to 4000 mg per day. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 30 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided in equal doses and taken every 6 hours. Depending on the severity of your infection, your doctor may increase your dose as needed. For oral dosage form (PCE® tablets): For prevention of recurring attacks of rheumatic fever: Adults—250 milligrams (mg) 2 times a day. Children—Use and dose must be determined by your doctor. For treatment of bacterial infections: Adults—333 milligrams (mg) every 8 hours or 500 mg every 12 hours. Depending on the severity of your infection, your doctor may increase your dose as needed up to 4000 mg per day. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 30 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided in equal doses. Depending on the severity of your infection, your doctor may increase your dose as needed.

Overdose

In case of overdosage, Ilosone should be discontinued. Overdosage should be handled with the prompt elimination of unabsorbed drug and all other appropriate measures should be instituted.

Ilosone is not removed by peritoneal dialysis or hemodialysis.

Storage

Store Ilosone at room temperature, below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep tightly closed. Keep Ilosone out of the reach of children and away from pets.

Side effects

The most common side effects associated with Ilosone are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Prescribing Ilosone Tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Since Ilosone is principally excreted by the liver, caution should be exercised when Ilosone is administered to patients with impaired hepatic function.

Exacerbation of symptoms of myasthenia gravis and new onset of symptoms of myasthenic syndrome has been reported in patients receiving Ilosone therapy.

There have been reports of infantile hypertrophic pyloric stenosis (IHPS) occurring in infants following Ilosone therapy. In one cohort of 157 newborns who were given Ilosone for pertussis prophylaxis, seven neonates (5%) developed symptoms of non-bilious vomiting or irritability with feeding and were subsequently diagnosed as having IHPS requiring surgical pyloromyotomy. A possible dose-response effect was described with an absolute risk of IHPS of 5.1% for infants who took Ilosone for 8 to 14 days and 10% for infants who took Ilosone for 15 to 21 days.5 Since Ilosone may be used in the treatment of conditions in infants which are associated with significant mortality or morbidity (such as pertussis or neonatal Chlamydia trachomatis infections), the benefit of Ilosone therapy needs to be weighed against the potential risk of developing IHPS. Parents should be informed to contact their physician if vomiting or irritability with feeding occurs.

Prolonged or repeated use of Ilosone may result in an overgrowth of nonsusceptible bacteria or fungi. If superinfection occurs, Ilosone should be discontinued and appropriate therapy instituted.

When indicated, incision and drainage or other surgical procedures should be performed in conjunction with antibiotic therapy.

Observational studies in humans have reported cardiovascular malformations after exposure to drug products containing Ilosone during early pregnancy.

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