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Glucotrol (Glipizide)

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Glucotrol belongs to the class of drugs known as sulfonylureas. It lowers blood sugar by causing the release of your body's natural insulin. Glucotrol is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications.

Other names for this medication:
Actizide, Bimode, Diabizide, Diacon, Diaglip, Dibimet, Dibizide, Glanase, Glibetic, Glicept, Glimet, Glipicon, Glipicontin, Glipid, Glipimet, Glipiriv, Glipitis, Glipixor, Glipized, Glipizide, Glipmet, Glucolip, Gluconil, Glumin, Glunas, Glycind, Glydal, Glylin, Glynase, Glysar, Glysin, Glyson, Glytop, Glyzip, Gpzide, Libiz, Metaglez, Metglib, Swiglip, Tranase, Zidmin

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Also known as: Glipizide


Glipizide is used to treat high blood sugar levels caused by a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. In type 2 diabetes, your body does not work properly to store excess sugar and the sugar remains in your bloodstream. Chronic high blood sugar can lead to serious health problems in the future.

Proper diet is the first step in managing type 2 diabetes, but often medicines are needed to help your body. Glipizide belongs to a class of drugs called sulfonylureas. It stimulates the release of insulin from the pancreas, directing your body to store blood sugar. This helps lower blood sugar and restore the way you use food to make energy.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain glipizide. It may not be specific to Glucotrol XL. Please read with care.

Follow carefully the special meal plan your doctor gave you. This is the most important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed.

This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.

Swallow the extended release tablet whole. Do not split, crush, or chew it.

If you are taking the extended release tablet, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For type 2 diabetes: For oral dosage form (extended-release tablets): Adults—At first, 5 milligrams (mg) once a day taken with breakfast. Your doctor may adjust your dose if needed. The dose is usually not more than 20 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 5 milligrams (mg) once a day taken at least 30 minutes before breakfast. Your doctor may adjust your dose if needed. The dose is usually not more than 40 mg per day. Children—Use and dose must be determined by your doctor.


If you overdose Glucotrol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Glucotrol overdosage: hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Glucotrol XL dosage information

Side effects

The most common side effects associated with Glucotrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of glipizide in the pediatric population. Safety and efficacy have not been established.

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Family presence during pediatric resuscitation: a focus on staff. Use of an exterior curtain-net to evaluate insecticide/mosquito behavior in houses. Treatment of ST-elevation myocardial infarction (STEMI) has changed significantly over the past two decades. The application of intraluminal thermal injury with a heat probe results in a reproducible animal model of benign biliary stenosis. Obesity at the beginning of pregnancy but not weight gain was related to low quality of life and daytime sleepiness at the third trimester of gestation. The p53 protein is widely regarded as an important sensor of genotoxic damage in cells, and mutations in p53 are the most frequent observed in human cancers. Solid and papillary epithelial neoplasm of the pancreas--a rare malignant tumor of pancreas. At the initial presentation, the keratitis involved the host cornea alone in case 1, whereas in case 2, the posterior lamellar disk alone was involved.

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The importance of ultrasonography in detecting pathology of the kidneys during ambulatory observation of patients with hemorrhagic fever with renal syndrome. The calmodulin and F-actin binding sites of smooth muscle caldesmon lie in the carboxyl-terminal domain whereas the molecular weight heterogeneity lies in the middle of the molecule. Thirty patients with American Society of Anesthesiologists physical status I and II scheduled for gynecological surgery. In this work, we present a well-scaling parallel CDFT implementation relying on a mixed basis set of Gaussian functions and plane waves, which has been specifically tailored to investigate condensed phase ET reactions using an explicit, quantum chemical representation of the solvent. This is the first report from India of a family of 4 sisters and 3 brothers in whom the proband showed a complete form of the choreo-acanthocytosis syndrome, whereas the 2 brothers who had died earlier of this disease had no examination of their blood.

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Botulinum toxin type A or local excision/curettage is effective for isolated axillary hyperhidrosis not responsive to topical application of aluminum chloride. Effects of dietary aflatoxin on existing bacterial intramammary infections of dairy cows. Rerandomization tests are presented as alternatives to analysis of variance and multivariate analysis for assessing group differences using such data. Objections, confusion among pharmacists threaten access to emergency contraception. Forty-eight GPA patients and 38 age-matched healthy donors were included in the study. Its overall goal was to strengthen the capacities of nongovernmental organizations (NGOs) in initiating and developing HIV/AIDS interventions at the grass-roots level. We present a self-organizing model of group formation in three-dimensional space, and use it to investigate the spatial dynamics of animal groups such as fish schools and bird flocks. Use of mathematical simulation models in health-environment systems. Each of these principles is discussed as it relates to abortion, and potential conflicts and controversies are assessed in accordance with the principles.

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Results revealed that patients with type 2 diabetes, who were carriers of the HMGA1 rs139876191 variant had a significantly lower risk of developing PDR, compared to non-carrier diabetic patients. Survival depends on prompt recognition and immediate medical and surgical therapy. Percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) is a common therapeutic method. Antibody responses to human herpesvirus 6 and other herpesviruses. In addition, we will discuss some of the newer developments in SNS such as Bion device and the future direction in integration of SNS in female urology. Sodium D-glucose cotransport in the gill of marine mussels: studies with intact tissue and brush-border membrane vesicles.

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