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Fasigyn (Tinidazole)
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Fasigyn

Fasigyn is an antibiotic, which belongs to a group of medicines called nitroimidazoles. Fasigyn works by killing or stopping the growth of bacteria causing your infection. Fasigyn will not work against viral infections such as colds or flu.

Other names for this medication:
Simplotan, Tindamax, Tinidazole

Similar Products:
Phenergan, Adalat, Nexium, Singulair, Eulexin, Zyloprim, Mircette

Also known as: Tinidazole

Description

Fasigyn manufacturer is Pfizer. Fasigyn tablets contain active ingredient is Tinidazole, a 5-nitroimidazole anti-parasitic agent, which belongs to a drug class Amebicides, Antimalarials and gynecological Antiinfectives.

Dosage

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Take Fasigyn with a glass of water during or after a meal. Swallow the tablets whole. It is best to take the medicine at the same time each day.

For bacterial infections, this medicine is not recommended for use in children less than 12 years as it has not been tested in this age group.

For protozoal infections, Fasigyn 500mg film-coated tablets can be used in children and has not been shown to cause any different side effects or more problems than it does in adults.

The dose and length of treatment depends upon the infection being treated. If you are on dialysis, your doctor may prescribe a different dose.

The doses most commonly used for the different infections are shown in the table below:

For treating the infection associated with stomach ulcers. The usual dose is 1 tablet (500mg) taken twice a day. Your doctor will probably prescribe two other medicines to be taken with Fasigyn 500mg film-coated tablets. Treatment with the three medicines together will usually be for 1 week.

For treating most bacterial infections. The usual dose is 4 tablets (2g) on the first day then 2 tablets (1g) once a day or 1 tablet (500mg) twice a day. The usual length of treatment is 5 to 6 days.

For treating bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection). The usual dose is 4 tablets (2g) given as a single dose. For vaginitis you may be given 4 tablets (2g) on two consecutive days.

For preventing bacterial infections after surgery. Usually 4 tablets (2g) are given as a single dose about 12 hours before surgery.

For treating protozoal infections. For treating intestinal amoebiasis (a stomach infection). Adult: The usual dose is 4 tablets (2g) once a day for 2 to 3 days. Child: The usual dose is 50 to 60mg/kg of body weight once a day for 3 days.

For treating amoebic involvement of the liver (a liver infection). Adult: The usual dose is 3 to 4 tablets (1.5 to 2g) once a day for 3 to 6 days. Child: The usual dose is 50 to 60mg/kg of body weight once a day for 5 days.

For treating giardiasis (an abdominal infection) and trichomoniasis (an infection of the sex organs in males and females). Adult: The usual dose is 4 tablets (2g) given as a single dose. Child: The usual dose is 50 to-75mg/kg of body weight given as a single dose.

Your doctor will calculate the dose required for a child and may repeat the dose once if the infection has not cleared up completely.

Overdose

Immediately telephone your doctor or go to Accident and Emergency (Casualty) at your nearest hospital if you think you or anyone else may have taken too much Fasigyn. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Keep telephone numbers of these places handy.

If you take too many tablets, you may get an upset stomach, diarrhoea or skin rashes.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Fasigyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Pregnancy: Fertility studies in rats receiving 100mg and 300mg tinidazole/kg had no effect on fertility, adult and pup weights, gestation, viability or lactation. There was a slight, not significant, increase in resorption rate at the 300mg/kg dose. Tinidazole crosses the placental barrier. Since the effects of compounds of this class on foetal development are unknown, the use of tinidazole during the first trimester is contraindicated. There is no evidence that Fasigyn is harmful during the latter stages of pregnancy, but its use during the second and third trimesters requires that the potential benefits be weighed against possible hazards to mother or foetus.

Breast-feeding: Tinidazole is excreted in breast milk. Tinidazole may continue to appear in breast milk for more than 72 hours after administration. Women should not nurse until at least 3 days after having discontinued taking Fasigyn.

No special precautions should be necessary. However, drugs of similar chemical structure, including Fasigyn, have been associated with various neurological disturbances such as dizziness, vertigo, ataxia, peripheral neuropathy (paraesthesia, sensory disturbances, hypoaesthesia) and rarely convulsions. If any abnormal neurological signs develop during Fasigyn therapy, the drug should be discontinued.

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