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Estrace (Estradiol)

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Estrace is a moderately priced drug used to treat hot flashes and osteoporosis. Take this medicine by mouth. To reduce nausea, this medicine may be taken with food. Follow the directions on the prescription label.

Other names for this medication:
Bestradiol, Conjugase, Divigel, Edval, Espauz, Estogen, Estraderm, Estradiol, Estrofem, Evafem, Evalon, Evaride, Menocare, Mixogen, Oestrogel, Premarin, Progynon, Progynova, Sandrena

Similar Products:
Inderal, Rulide, Fasigyn, Bystolic, Amoxil, Addyi, Colcrys

Also known as: Estradiol


Estrace is used to treat symptoms of menopause (hot flashes, vaginal dryness, burning and irritation), prevent osteoporosis. Estrace is sometimes used as part of cancer treatment in women and men. Estrace medication is a form of estrogen - female hormone necessary for many processes in the body. Estrace works by replacing natural estrogens in a woman who can no longer produce enough estrogen. Estrace works for advanced prostate cancer by antagonizing male hormones. Estrace is also known as Estradiol.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Estradiol may increase your risk of developing a condition that may lead to uterine cancer. Your doctor may prescribe a progestin to help lower this risk. Call your doctor at once if you have any unusual vaginal bleeding.

Wash your hands before and after inserting Estrace Vaginal.

Use the applicator provided to measure the prescribed dose of estradiol vaginal cream. Take apart the cream applicator and wash it with mild soap and warm water after each use.

Each Estrace Vaginal tablet is supplied in a single-use disposable applicator. Throw the tablet applicator away after one use.

You should not be able to feel the vaginal ring once it is in place. Leave the vaginal ring in place for 90 days, then remove it. Your doctor may want you to replace it with a new ring. The ring does not need to be removed during sexual intercourse. If the ring is bothersome, you may remove it, rinse it with warm water, and reinsert it after intercourse.

To remove the ring, loop a finger through the ring and gently pull it from the vagina. Call your doctor if you have trouble removing a vaginal ring.

Your doctor should check your progress on a regular basis to determine whether you should continue this treatment. Self-examine your breasts for lumps on a monthly basis and have a mammogram every year while using estradiol.

If you need major surgery or will be on long-term bed rest, you may need to stop using Estrace Vaginal for a short time. Any doctor or surgeon who treats you should know that you are using estradiol.

Store at room temperature away from moisture and heat. Keep the vaginal ring in its protective pouch until you are ready to use it.

Detailed Estrace Vaginal Cream dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Wrap the used vaginal ring in tissue or toilet paper and throw it in the trash can. Do not flush it down the toilet.

Detailed Estrace dosage information

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Although appropriate studies on the relationship of age to the effects of estradiol vaginal gel, insert, or ring have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have breast cancer, strokes, or dementia, which may require caution in patients receiving estradiol vaginal gel, insert, or ring.

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