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Devita (Calcitriol)
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Devita

Devita is a hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give Devita.

Other names for this medication:
Admax, Alfabond, Alfacal, Alfacalcirol, Alfarich, Alphadol, Apcical, Arcium, Biocal, Biocitral, Calbory, Calcicare, Calcikind, Calcit, Calcor, Calday, Caldikind, Caldix, Calgel, Calotec, Calsonic, Caltin, Caltop, Carcal, Coecoral, Denscal, Duracal, Fovit, Koncal, Lctrol, Minroset, Novadee, Nutribone, Ostriol, Politrol, Primacal, Qpcal, Refirm, Riecal, Ritoca, Rockbon, Roical, Rolsical, Sorvate, Statbone, Sunmic, Tobalt, Zaxial

Similar Products:
Trandate, Yasmin, Ditropan, Dostinex, Xanax

Also known as: Calcitriol

Description

Generic Devita is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Devita are intestine and bone. Generic Devita receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Devita may also act on the kidney and the parathyroid glands. Generic Devita is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Devita has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Devita, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Devita in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Devita produces other independent beneficial effects. Devita is also known as Calcitriol. Generic Devita treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Devita is Calcitriol. Brand name of Generic Devita is Devita.

Dosage

This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Rocaltrol. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Devita and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Devita are:

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Contraindications

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

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A molecular caliper mechanism for determining very long-chain fatty acid length. A total of 1012 articles fulfilled the search criteria, 32 of which were included in the study. These data support the clinical observation of augmented ototoxicity in patients receiving combined gentamicin and metronidazole. Paracetamol analysis: evaluation of a new kit for enzymatic assay. However, more recently MC has been tested even in the adjuvant/neoadjuvant setting, taking the opportunity to obtain tumor specimens and blood samples, in order to identify tumor-specific or patient-specific biomarkers for personalizing treatments. Piezo2 is an important mechano-gated ion channel that is involved in light touch sensitivity and inflammatory allodynia. We aimed to investigate how worries about modernity affecting health, negative affectivity, and prior symptom complaints influence health complaints after environmental spraying in a prospective study.

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Revealed in the study were both a positive clinical effect of the above-named drug and its protective action with respect to systemic resorption of the osseous tissue in patients with rheumatoid arthritis. In addition, the proposed model may shed light on the mechanisms of RNP shaping and could allow the identification of essential amino acid residues as potential targets for tospovirus control strategies. T-DNA knockout mutants for five of the seven FRKs were identified and used in this study. Sperm cells contained only arylsulfatase A, which differed biochemically from the extracellular arylsulfatase A of seminal plasma (2.6 units per ml). Using a reanalysis of Diabetes Prevention Program, this study aimed to estimate the causal effect of treatment with intensive lifestyle intervention or metformin vs. Another inhibitor, BG-2 (Gly-Lys-Met-Val-Lys-Val-Val-Ser-Trp-Tyr, IC50: 6 microM), correspond to GAPDH peptide 304-313. Procedures are presented for isolating fractions of long-chain polyphosphates which have a narrow range of sizes and for determining their chain lengths. An electronic deoxyribonucleic acid (DNA) microarray technique was developed for detection and identification of viable Escherichia coli O157:H7, Vibrio cholerae O1, and Salmonella typhi. High-resolution MALDI Fourier transform ion cyclotron resonance mass spectrometry (HR MALDI-FT-ICR) and 1H NMR experiments provide evidence that HS- coordination occurs at the zinc centre.

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We then turn to the full model and find the same transition, both analytically and numerically, proving that this transition in not limited to nascent bistability regimes. By confocal microscopy we show that Rab6A, mint3 and APP co-localize at Golgi membranes in HeLa cells. Nifedipine GITS and hydrochlorothiazide in essential hypertension. High resolution kilometric range optical telemetry in air by radio frequency phase measurement. Although administration of either agonist alone induced increases in forward locomotion and/or sniffing behavior at all test ages, the adult-typical grooming response to SKF-38393 and increase in vertical movements in response to quinpirole were not evident until weaning. The accumulation of Cdc6 promotes the initiation of DNA replication. Control animals showed a relatively uniform polarization state in the five brain areas. The sensitivity of this assay (ED50 at 100 pM) allowed the direct measurement of RLF concentrations in serum. In animal models, chemokines are produced at the site of injury, leading to inflammatory cell recruitment.

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The significance of a behavioral approach to bruxism: theoretical aspects and therapeutic perspectives. Although, to our knowledge, no cellular roles for plant LC8 family members have been proposed, we hypothesize that binding of LC8 proteins to Gag aids in the movement of retrotransposon virus-like particles within the plant cell or possibly induces important conformational changes in the Gag protein. Specific phobia and major depressive disorder had the highest attributable fractions for all-cause sick leave. Neuroimaging revealed pontine curvilinear enhancing lesions with extension into cerebellar peduncles, characteristic of CLIPPERS. Taken together, these results demonstrated that there is a serotype-specific difference in the ability of the reovirus attachment protein, sigma 1, to interact with sialylated oligosaccharides of glycoproteins. The center wavelength, spectral width, and pulse width of the laser output are 1558.8 nm, 14.2 nm, and 805 fs, respectively. Results were compared statistically by using t tests and Mann-Whitney rank sum tests. A blood test revealed elevated levels of the tumor markers, CEA(12.1 ng/ml), SLX (134 U/ml) and CA19-9 (76.2 U/ml). The advanced life support base hospital audit for medical control in an emergency medical services system.

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The multitude of therapies in metastatic colon cancer have led to longer overall survival with fewer symptoms. Hypotheses were that work, personal, family, and health concerns, as well as time zone travel, contribute to travel stress. These peptides are fragmentation products of an M(r) 36,000 asparaginase subunit. The Role of Computed Tomography in the Diagnosis of Relapsing Polychondritis. The influence of factors from the dogs living environment is discussed.

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DETERMINATION OF THE CONTENT OF ETHEREAL OILS IN SOME GALENIC PREPARATIONS IN ALCOHOL. how much is albendazole tablet Our study revealed a high prevalence of psychotropic medications and inappropriate drug use among older homebound residents, a group that is at the highest risk for adverse drug reactions. Fifteen of 49 frailty measures included components across all three domains. Observation on the leucocyte reaction from the standpoint of the fields of blood defense reaction with special reference to the three basal forms of leucocyte reaction. The wide range of information about the heart structure and function is feasible to achieve due to advanced techniques of magnetic resonance imaging and the ima-ging is not limited by acoustic windows as it is in case of echocardiography.

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Future research on the relationship between diet and mental health in young people should use more clearly defined constructs to define diet and include or control for important confounders. To obtain gene sequences controlling the early steps of amphibian neurogenesis, we have performed differential screening of a subtractive cDNA library prepared by a novel PCR-based method from a single presumptive neural plate of a Xenopus laevis late-gastrula embryo. Use of the insulin pump does not appear to be different from MDI in the frequency of occurrence of hypoglycemia. Ciclosporine for the treatment of refractory idiopathic thrombocytopenic purpura. In a relatively small number of patients with congenital AT III deficiency it is necessary, under certain condition to substitute AT III. These results indicate that targeting the autophagic pathway could be a novel therapeutic strategy for DLBCL and that precaution should be taken to interpret data where tenovin-6 was used as an inhibitor of sirtuins. Memory and socioemotional behavior in monkeys after hippocampal damage incurred in infancy or in adulthood. In contrast to its role in nuclear polyadenylation, cytoplasmic PABP2 acts to shorten the poly(A) tails of specific mRNAs. Muscle glycogen concentrations were similar between MFM cases and controls.

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