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Compazine (Prochlorperazine)
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Compazine

This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment). Compazine belongs to a class of drugs known as phenothiazines. Take this medication by mouth with or without food as directed by your doctor, usually 3 to 4 times daily.

Other names for this medication:
Bukatel, Compro, Emidoxyn, Eminorm, Ingametil, Meditil, Neurocin, Neurograin, Neurolice, Neuromol, Neuronit, Novapar, Nuroflow, Nuropar, Prochlorperazine, Procomp, Psygrain, Stemetil, Swigrain, Vasograin, Vertipro, Vestil

Similar Products:
Clozaril, Avelox, Azulfidine, Avodart, Elavil

Also known as: Prochlorperazine

Description

Generic Compazine is taken for controlling severe nausea and vomiting and treating schizophrenia. It is also used for the short-term (4 weeks) treatment of generalized nonpsychotic anxiety. It may also be used for other conditions. Generic Compazine is a phenothiazine. It works by blocking a certain chemical (dopamine) in the brain. Compazine is also known as Prochlorperazine, Compro, Stemetil, Stemzine. Generic name of Generic Compazine is Prochlorperazine. Brand name of Generic Compazine is Compazine.

Dosage

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets): For severe nausea and vomiting: Adults and children 2 years of age and older and weighs more than 39 kilograms (kg) (85 pounds (lbs))—At first, 5 or 10 milligrams (mg) 3 or 4 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 40 mg per day. Children 2 years of age and older and weighs 18 to 39 kg (40 to 85 lbs)—Dose is based on body weight and must be determined by your doctor. At first, 2.5 mg 3 times a day or 5 mg 2 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 15 mg per day. Children 2 years of age and older and weighs 14 to 18 kg (30 to 39 lbs)—Dose is based on body weight and must be determined by your doctor. At first, 2.5 mg 2 or 3 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 10 mg per day. Children 2 years of age and older and weighs 9 to 13 kg (20 to 29 lbs)—Dose is based on body weight and must be determined by your doctor. At first, 2.5 mg 1 or 2 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 7.5 mg per day. Children younger than 2 years of age and weighs under 9 kg (20 lbs)—Use is not recommended. For non-psychotic anxiety: Adults—At first, 5 milligrams (mg) 3 or 4 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 20 mg per day or longer than 12 weeks. Children—Use and dose must be determined by your doctor. For schizophrenia: Adults—5 to 10 milligrams (mg) 3 or 4 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 150 mg per day. Children 6 to 12 years of age—At first, 2.5 mg 2 or 3 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 10 mg on the first day and 25 mg per day. Children 2 to 5 years of age—At first, 2.5 mg 2 or 3 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 10 mg on the first day and 20 mg per day. Children younger than 2 years of age—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Compazine and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Compazine dosage information

Side effects

The most common side effects associated with Compazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of prochlorperazine in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Sustained attenuation of neointimal coverage over the stent following brachytherapy for in-stent restenosis: angioscopic findings. The authors describe a multi-specialist model of extensive treatment of voice disorders in a health spa, including holistic and interdisciplinary procedures in occupational dysphonia. A unique site-selectivity switch has been achieved in the ruthenium-catalyzed C-H arylation reaction of N-acetyl-1,2-dihydroisoquinolines. The delipidated apoprotein of both human and rat HDL caused similar stimulation of 6-keto-PGF1 alpha production, but much less than intact HDL. Various universal primers amplified both plant and microbial sequences, with different primers revealing different patterns of fungal diversity. Experimental results indicate that the erosion of the hydrogel layer is the main delivery process. SR-BI, the first identified high-density lipoprotein (HDL) receptor, plays key roles in reverse cholesterol transport by promoting selective uptake of cholesteryl esters (CE) in HDL by hepatocytes, and cholesterol efflux of unesterified cholesterol from peripheral cells to HDL. Temporally, the mRNA expression reached the top level at 6 approximately 8 hours and remained high 12 hours after the stimulation.

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Graphic, verbal, and numerical data, incorporated into a master computerized system, record events of each family member: training programs experienced, health care delivery courses taken, medical treatments, growth of children, literacy changes, educational courses completed, kinds and amounts of foods eaten, household and building materials purchased. Three independent methods, which have been developed and used so far for one-dimensional maps, have been used to accomplish this task. DNA restriction fragment length analysis of the human class II genes (DR,DQ) of bone marrow transplant donor-recipient pairs by DNA-DNA hybridization. Flaxseed, the richest source of mammalian lignan precursors, has previously been shown to reduce the growth of tumors in rats. The present study evaluated the potential for phorbol myristate acetate-differentiated THP-1 cells to mimic this response of primary macrophages. Alterations in the activity of Cu,Zn-superoxide dismutase (SOD1), an enzyme that converts superoxide (O(.-)(2)) to hydrogen peroxide (H(2)O(2)) plus O(2), have been found to affect cellular susceptibility to oxidative stress and have been invoked as a pathogenetic mechanism in a variety of neurodegenerative diseases. The calculated wavefront distortion is tomographically inverted to yield the density distributions of the object.

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Muscle activation and its distribution within human triceps surae muscles. Iatrogenic injury of the common iliac artery: a rare complication of disk prolapse surgery in the lumbar area. In four of six patients, the entire ileum or its more distal part was markedly narrowed. From the results of our research, it was clarified that the aggregated microorganisms consisting of biofilm had high potential for degradation of intracellular and dissolved microcystin. Racial/ethnic differences in receipt of pelvic lymph node dissection among men with localized/regional prostate cancer.

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plantarum) KY1032 reduced the body weight, body fat percentage, body fat mass and L1 subcutaneous fat area in overweight subjects. These effects were found to be dependent on the dose of the toxin and the time of exposure of the P2 fraction to notexin. Here, through crystallographic analyses we show that the SUMO E2 Ubc9 forms a noncovalent complex with a SUMO-like domain of Rad60 (SLD2). Treatment of cells with phorbol 12-myristate 13-acetate (PMA), an activator of PKC, suppressed DNA fragmentation induced by PCBs in HL-60 cells. Non-indigenous species have caused prominent structural changes in invaded communities as a result of exponential increase in the most recent invasions, as well as increased densities of the already established alien species. These results indicate that Lys36 and Arg211 participate in a complex hydrogen bond network that connects the C-terminal D-Ala residues to the phosphate groups of UDP-MurNAc-pentapeptide and constrains the substrate in a conformation that is essential for transferase activity. We also compared age-related changes of PSA-forms in blood from young versus older men. A clear understanding of these modalities and their relative merits is mandated by the potential severity of cervical injuries and their need for rapid intervention. Replicated, high-aspect-ratio micro-optical components fabricated from inorganic solgel materials.

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In total, 3670 patients were treated with percutaneous, laparoscopic or open RFC. Phylogeny of the subgenus Culicoides and related species in Italy, inferred from internal transcribed spacer 2 ribosomal DNA sequences. Surgical treatments appear to provide some benefit to patients refractory to nonsurgical therapies. RpoS, the sigma factor of enteric bacteria that responds to stress and stationary phase, is subject to complex regulation acting at multiple levels, including transcription, translation, and proteolysis. Here, we show that peripherin overexpression slows down axonal transport of neurofilament (NF) proteins, and that the transport defect precedes by several months the appearance of axonal spheroids in adult mice. The density of vWF and VEGF positive vessels, VEGF staining intensity and the number of VEGF positive stromal, epithelial and vascular endothelial cells were evaluated. Exposure to soiled bedding from estrous females or the display of coital behaviors rapidly (within 10 min) induced MAPK phosphorylation in most of the brain regions known to be involved in the processing of olfactory cues (main and accessory olfactory bulbs, amygdala, and medial preoptic area) and in the control of copulatory behavior (amygdala and medial preoptic area). This review focuses on molecular epidemiology and primary prevention aspects of the small non-coding RNA sequences. HOXA repression is mediated by nucleoporin Nup93 assisted by its interactors Nup188 and Nup205.

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After pyrolysis at 1073 K in N2/NH3 atmosphere, the synthetic nanowires are discrete and curly with diameters about tens of nanometers and lengths of hundreds of nanometers. Further, the cytokine cascade is involved in the process of atherogenesis, and exercise-induced changes in cytokine production may expose latent HIV to chemotherapeutic agents. Set-up (training, equipping and planning) costs per HBC site, HBC operating costs (total and average cost per patient), and average hospital inpatient, hospital outpatient and primary care clinic cost per participating patient. After two years exposure a significant decrease of mean expiratory flow (MEF)50 and MEF25 was found. A prospective hospital-based study was performed in a sample of 22 women with EOBC (7 in clinical stage IIA, 8 in IIB, and 7 in IIIA). Context matters: Anterior and posterior cortical midline responses to sad movie scenes.

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During the 1990s, bioethicists raised questions about certain clinical trials conducted in developing countries. This work reports studies of the degradation rates of a fatty alcohol polyglycol ether non-ionic surfactant, Genapol OXD-080, putatively useful for the control of red swamp crayfish (Procambarus clarkii Girard) in rice fields under laboratory and field conditions. A microwave tuned to a frequency below the gyrofrequency forces electrons moving towards the microwave to absorb a microwave photon. The modified technique describe herein was used in 11 procedures. All features are obtained from images visualized by off-axis digital holographic microscopy with a numerical reconstruction algorithm, and four categories of biconcave (doughnut shape), flat-disc, stomatocyte, and echinospherocyte RBCs are interested. We introduced human genes into the Ade2 and Ade3 cells by chromosome-mediated gene transfer. PVN galanin increases fat storage and promotes obesity by causing muscle to utilize carbohydrate more than fat. Results are pending as to whether cinacalcet decreases mortality and morbidity in pHPT, confirmation of which would conclusively recommend this drug as a valid alternative to surgery.

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The developed approach is used to investigate the influence of the background gas on the expansion dynamics of the plume obtained during the laser ablation of aluminum. Identification of local conformational similarity in structurally variable regions of homologous proteins using protein blocks. We identified a previously reported missense mutation of G857R in one allele of FLT4 from three affected individuals of three generations, the mother of whom presented only hemi-lymphedema of the left foot. The purpose of this study was to investigate the possible correlations between digit ratio, oral squamous cell carcinoma (OSCC)-the most common oral cancer-and oral premalignant lesions (OPLs) in tobacco-consuming males, the main risk group for this disease. To assess the safety and efficacy of a dolutegravir-based regimen in perinatally HIV-1-infected adolescents. Normal stem cells exhibit an attenuated DNA damage response (DDR), inefficient DNA repair, and high radiosensitivity. Determination of plasma topotecan and its metabolite N-desmethyl topotecan as both lactone and total form by reversed-phase liquid chromatography with fluorescence detection. Prophylactic vaccination with HPV16 L1 virus-like particles (VLPs) provides immunity.

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The structure--crystallite size--physical-chemical property relationship is also considered. Magic and myth of migration: a case study of a special economic zone in China. There was also no increase in the number of intravascular neutrophils within the bronchial vessels after treatment with anti-PECAM-1 antibody. There was no evidence of shifts in cell populations contributing to the X chromosome inactivation patterns in recipient marrow grafts when compared with their respective donors. Relationships between chemical structure and inhibition of ADP-stimulated human thrombocyte release of serotonin and platelet factor 4. Subsequently, a viscous instability is observed for sufficiently large withdrawal speeds or sufficiently low gravity components on the model.

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We report here the results of a prospective epidemiological study of Creutzfeldt-Jakob disease in continental France during the years 1978-80, extending a retrospective study of the decade 1968-1977 previously reported. Cigarette smoke suppresses TLR-7 stimulation in response to virus infection in plasmacytoid dendritic cells. We demonstrate that in each case, this discrimination and some of the more complex conductance properties of the channels is a consequence of the electrostatic interaction of the ions with the charges in the channel protein. Structural studies of the wild-type enzyme have demonstrated that the active site consists of a binuclear metal center positioned at the C-terminal end of a (beta/alpha)(8)-barrel domain. Whether the identified indicators can be compiled into a prognostic instrument requires confirmation in a properly designed and flagyl 400 mg tablet price sized study. We then integrate the pathway based results of all the three cancers which provide a more comprehensive picture of the three cancers.

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Fructose-1,6-bisphosphate (FBP), an endogenous intermediate of glycolysis, protects the brain against ischemia-reperfusion injury. Non-commercial clinical trials of a medicinal product: can they survive the current process of research approvals in the UK?. DIFFUSION: weighted MRI (DWI) is a novel technique that analyzes the diffusion of water molecules in vivo. When shock was produced by the first response occurring after 8 min (8-min fixed-interval schedule), a period of no responding at the beginning of the interval was followed by a gradual increase in response rate during the interval. Extreme ultraviolet radiation produced with high degree of ellipticity (close to circular) is demonstrated. Bovine prochymosin (bPC) is an inactive precursor of the milk clotting enzyme chymosin (EC 3.4.23.4), that is present in the abomasum of suckling calves. In particular, they involve cooperation with the Population Division in the areas of intergration of demographic variables into planning, aging and differential mortality.

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The depressions in RBC, WBC, and neutrophils observed in this study are not only exposure dependent, but also significantly different in the lowest exposed group (at or below 0.25 ppm) compared with unexposed subjects. Two newly recognized laminins, 8 and 10, are the major laminins produced by human dermal microvascular endothelial cells. To improve this poor prognosis the symptoms should be well noticed and operation should be performed within four to six hours. The objective was to study outcome data in home TPN-dependent children and to describe precisely their liver biopsies in the attempt to analyze risk factors for biochemical and histological hepatic abnormalities. Treatment of radiation sickness with pyridoxine hydrochloride in outpatients of a radiotherapy unit. This massive NO release was not caused by activation of the neuronal NO synthase (nNOS), but by increased expression of the inducible NOS (iNOS) mRNA and protein. At the end of the fourth culture week the rates of (pro) insulin biosynthesis were similar in all three experimental groups. Control of phase synchronization of neuronal activity in the rat hippocampus. These data are consistent with a model for the binding of peptide ligands to the GLP-1 receptor in which the central and C-terminal regions of the peptides bind to the N terminus of the receptor, whereas the N-terminal residues of peptide agonists interact with the extracellular loops and transmembrane helices. Second, a group of 15 patients thus rocaltrol tablet trained was compared with 8 others who received traditional physiotherapy modalities.

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The incidence of oral sinus communications (OSC) following the extraction of an upper third molar remains uncertain. Change in optic disc cupping was evaluated in a 4-year follow-up of a well defined cohort of people with diabetes mellitus. The data, in combination with previous work, thus provide a picture of the intra-specific response of a suite of traits to can you give a dog zyrtec allergy medicine ecological stress. To determine the reasons why men fail to participate in a free prostate cancer screening. Evolution of the number of LRRs in plant disease resistance genes. The strategy can model different scenarios network reconfiguration by adjusting the weight vector based on the tendencies of the utility decision maker. Immunofluorescence and immunoblotting revealed that some of the plectin-like proteins were present in perinuclear region or localized near the cell wall, probably being attached to the cytoplasmic membrane. We examined the sero-prevalence of mumps antibodies in the subpopulations subsequently affected by this large mumps outbreak, compared with the general population. Over a period both a monetary and physical measure of antihypertensive drug consumption has increased in Denmark, but the consumption has varied considerably between counties in any given year.

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To analyze the relationship between prevalence of metabolic syndrome (MS) and behavior habits such as smoking, alcohol intake, physical activity, sleeping hours. Inhibition of prostaglandin synthesis does not alter the decrease in pre-capillary resistance in the human calf in response to small cumulative increases in venous congestion. The benefits and dangers inherent to the various transplantation strategies are discussed. Fn14 and TWEAK are expressed in macrophages and smooth muscle cells in carotid atherosclerotic plaques. It is especially regarding prevention among vulnerable groups and the implementation of alternative care/support strategies for people living with HIV/AIDS (PHIV) that the NSAP cooperates most directly with NGOs. The aim of this study was to investigate whether how much does ativan cost in us the new strategy of combining drug-loaded nanoparticles (Nps) and ultrasound (US) would show useful effects on the reversal of MDR in tumor. Renal and liver dysfunction are frequently associated with use of folk remedies, and mortality in these patients is high. Here, we investigate which mechanisms are possibly involved in this effect in primary cultures of hippocampal astrocytes using glutamate agonists and glutamate uptake inhibitors. Force-driven unbinding of proteins HU and Fis from DNA quantified using a thermodynamic Maxwell relation. RNA Structural Determinants of Optimal Codons Revealed by MAGE-Seq.

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Giant cell arteritis in a patient with acute aortic insufficiency with thyrotoxicosis. Effects of retention interval on recall by mentally retarded subjects. We observed elevated risks for preeclampsia, preterm birth, and very preterm birth from maternal exposures to traffic air pollutants measured at ambient stations (CO, NO, NO(2), and NO(x)) and modeled through CALINE4 (NO(x) and PM(2.5)) and LUR (NO(2) and NO(x)). All included athletes were assessed for the presence of articular cartilage lesions, meniscal pathology, and the presence of effusions. It is ticlopidine 250 mg essential that first-line staff are able to prevent, make early diagnosis and provide prompt management of primary PPH. Total peripheral resistance was characterized by an immediate fall of short duration followed by a continuous rise above baseline after 120 min. Human topoisomerase I interacts with and phosphorylates the SR-family of RNA splicing factors, including ASF/SF2, and has been suggested to play an important role in the regulation of RNA splicing. Two patients undergoing hemodialysis for 19 and 13 yr, respectively, developed intestinal infarction with extensive amyloid deposits in the muscle layer and blood vessels. Discovery of Phenylglycine Lactams as Potent Neutral Factor VIIa Inhibitors.

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We measured the scattering radiation dose coming from the accelerator head and that due to irradiation volume. Oxime palladacycles revisited: stone-stable complexes nonetheless very active catalysts. Alcohol dehydrogenase substrate specificity in a colloidal solution of water in an organic solvent. Postactivation potentiation and its practical applicability: a brief review. NK4 gene therapy has confirmed antitumor efficacy on cancers with intact HGF-cMET signaling pathway. In normal subjects in whom plasma insulin concentrations rose significantly (239 uU/ml) and the blood level of 15 of the 18 amino acids measured fell significantly. PRA expression in intermediate trophoblastic cells was significantly higher in elective abortions (control group) compared to miscarriages. (3) BcaCD885 cells were labeled by QD800 (BcaCD885/QD800), then transwell chambers and wash way were used to detect the difference of invasion and metastasis ability between BcaCD885/QD800 and BcaCD885 cells. When the number of infants who died of congenital anomalies and severe alloimmunization disorders were included, the gross perinatal mortality rate for the controls was 44.03 while that of the cases was 18.75.

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Purification of these metabolites was achieved using combinations of gel filtration and high-performance liquid chromatography. Follow-up of screening patients conservatively treated for cervical intraepithelial neoplasia grade 2-3. This study hypothesized that p38 MAPK activation is required for spontaneous autoimmune renal injury in MRL-Fas(lpr) mice, resembling human lupus erythematosus. A recurrent neural classifier is proposed for the classification of the four mental states. Proopiomelanocortin (POMC) is the precursor protein of different hormones and neuropeptides, and the POMC-derived peptides are produced through proteolytic cleavage.

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The effect upon simple animal behavior of different frequencies of reinforcement, Part II: separate control of the reinforcement of different IRTs. Is Fixing Pediatric Nail Bed Injuries With Medical Adhesives as Effective as Suturing?: A Review of the Literature. The toolbox has a graphical user interface which facilitates the application of different reaction models to the data to generate the coupled differential equations. Differences in design and implementation of clinical research on hypertension treatment with acupuncture and moxibustion were analyzed in this article so as to provide experiences to the design of clinical research on its treatment. Plasmid pRO103 constitutively expressed the TFD pathway, and this allowed the metabolism of PAA in the absence of the inducer, TFD.

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Progress in Spinobulbar muscular atrophy research: insights into neuronal dysfunction caused by the polyglutamine-expanded androgen receptor. Statins exert beneficial effects in septic patients although the mechanisms remain elusive. Benthic cyanobacteria from aquatic environments have been reported to produce biologically active metabolites. Evaluation of the small third-trimester fetus using the foam stability index test. A high-flow intravenous spike and drip chamber was cut through the drip chamber and used as the sole apparatus for performing cricothyrotomy on unembalmed cadavers whose anterior neck surfaces and deep tissues were warmed to or near body temperature. PAEE (MJ/d) was assessed by heart rate monitoring, individually calibrated by using the FLEX heart rate method. Individuals aged 65 and older from a means-tested health plan in does differin gel work 1997, 2002, 2007, and 2012 (range 78,489-133,884 individuals). Cholesterol metabolism: a potential therapeutic target in Mycobacteria. High performance field-effect transistors fabricated with laterally grown ZnO nanorods in solution. Transplantation of bone marrow cells with changed haemoglobin type.

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