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Cardiorex (Diltiazem)

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Cardiorex is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle during depolarization.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilocor, Dilter, Diltia, Diltiaz, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Taztia, Tiamate, Tiazac

Similar Products:
Yasmin, Remeron, Exelon, Aygestin, Rocaltrol, Phenergan, Thorazine, Diovan, Persantine, Urispas

Also known as: Diltiazem


Diltiazem is used to control rapid heartbeats or abnormal heart rhythms. It belongs to a group of drugs called calcium channel blocking agents. Diltiazem affects the movement of calcium into the cells of the heart and blood vessels. As a result, the heart beats slower and the blood vessels relax, thus, increasing the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


Take Cardizem exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole.

Use Cardizem regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

You should not stop using Cardizem suddenly. Stopping suddenly may make your condition worse.

If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Your blood pressure will need to be checked often. You may also need frequent blood tests.

Store Cardizem at room temperature away from moisture and heat.

Detailed Cardizem dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cardizem LA dosage information

Side effects

The most common side effects associated with Cardiorex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of diltiazem in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving diltiazem.

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Information flow in the mental lexicon during speech planning: evidence from event-related brain potentials. In addition, Sanger sequencing was used to verify the pedigrees. Probable metachromatic leukodystrophy/pseudodeficiency compound heterozygote at the arylsulfatase A locus with neurological and psychiatric symptomatology. In this study we investigated for the first time the effects of night length on circadian phase shifts to light in humans. Emerging roles for orphan G-protein-coupled receptors in the cardiovascular system. However, that explanation does not hold for ultraviolet exposure from tanning beds, which in this study is associated with a significant increase in all cause mortality and cancer mortality.

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The future of prevention lies in immunizations, and if past and current successes with smallpox, polio, rubella, and measles vaccination programs are any indication, the future is bright for the developing fetus. Spectral-Domain Optical Coherence Tomography in Older Patients With History of Retinopathy of Prematurity. Ten patients with renal transplant artery stenosis were treated with percutaneous transluminal angioplasty (PTA). The SPODOBASE is constructed in such a way that other ESTs from S. This reinforces the concept of a more diffuse injury to brain in sick premature infants than is apparent from the appearance of current neuroimaging techniques. Twenty patients were enrolled for both pharmacokinetic and clinical studies. HpSA testing showed good sensitivity and specificity, even with frozen stool samples stored for up to 225 days. Nanostructured lipid carriers as novel carrier for parenteral delivery of docetaxel. Self-organized inorganic nanoparticle arrays on protein lattices. Did the gradual loss of GLUT2 cause a shift to diabetic disorders in the New Zealand obese mouse (NZO/Hl)?.

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The health-promoting properties of Se are due to vital functions of selenoproteins in which selenium is present as selenocysteine, the 21st amino acid. Forty-eight observational studies of VAP incidence and 43 interventional studies of SDD and other methods of VAP prevention were sourced from 10 reviews. The author notes that there has been a general movement of Christians from isolated communities toward the Christian redoubt in north central Lebanon. There is a general apprehension that Western interest will amount to interference in the internal affairs of newly independent countries. Federal law obligates health care providers receiving federal funding to ensure language access to limited English-proficient (LEP) individuals who cannot communicate with their provider.

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Increased activity was seen only with vinylidene chloride, the positive control. Furthermore, enforced expression of sense Nif3l1 RNA, but not antisense RNA, enhanced the neural differentiation of P19 cells accompanying the intense down-regulation of Oct-3/4 mRNA expression and the rapid induction of Mash-1 mRNA expression. The images are used to measure the areas of metabolite-bearing tissue in selected sections through the subject, and 31P spectra are acquired from the same section, together with a concentration reference located on the periphery. Prediction of percentage body fat in rural thai population using simple anthropometric measurements. While recent studies have identified some of the molecular mechanisms resulting in extreme insulin resistance in peripheral tissues and liver, these studies have resulted in relatively few advances in therapy. This study investigated the amount and cost of surgical prophylaxis in a representative general hospital in Taiwan in order to determine an appropriate course of action to control antibiotic use and decrease the burden of resistance.

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These two processes share common molecular mechanisms that have been highly conserved through evolution. The present work suggests that novel recombinant peptides may be safe and effective agents for the treatment of various inflammatory diseases. We reviewed the posttrial records of 73 patients with mCRC who participated in 1 of 3 clinical trials that examined a combination of gefitinib or erlotinib with standard cytotoxic chemotherapy. The increase in activity was not accompanied by an increase in binding titer, indicating that signal transduction occurred at lower levels of receptor occupancy. In addition, there appears to be a great degree of inter- and intraindividual variability in these hormonal responses.

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After further controlling for history of alcohol dependence and frequency of heavy drinking those first drunk before age 13 had a 1.5 times greater odds of unplanned sex and a 1.7 times greater odds of unprotected sex reportedly because of drinking. H3K9me2/3 binding of the MBT domain protein LIN-61 is essential for Caenorhabditis elegans vulva development. Two of these classes may represent lesions in the structural genes for nitrate reductase subunits A and C. Fetal intracardiac tumors are rare but, when present, are a common cause of poor or uninterpretable fetal heart tracings due to fetal arrhythmias. Using the electron microscope, we have conducted a morphometric analysis of cells in the lowest one-third of the lower tubule, demonstrating that 5-HT also induces mitochondrial movement and microvillar growth simultaneously with, but independent of, the onset of ion transport. Descriptions of psychiatric care in some hospitals during the first half of the 19th Century. RISUG (reversible inhibition of sperm under guidance)--an antimicrobial as male vas deferens implant for HIV free semen. An online anonymous questionnaire translated into ten languages contained questions regarding the importance and availability of information and support about HD related topics, and attitudes towards research.

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Selected abstracts from the Journal of the Experimental Analysis of Behavior, July 1993. An endoscopy unit in each of 2 acute district general hospitals in the United Kingdom. Nonetheless, both treatment options were associated with excellent 12-month secondary patency. Moreover, the inhibitory effect of a PKCzeta antagonist with sequences based on the endogenous PKCzeta pseudosubstrate region was weaker than the inhibitory effect on N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced O(2)(-) production. This survey reviews the aetiological background of neuropathy and ischaemia, examines the relationship of physiological blood flow abnormalities to both areas and comments on management of the clinical states encountered, including the common problem of the ulcerated diabetic foot.

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Killing time for cancer stem cells (CSC): discovery and development of selective CSC inhibitors. Significantly lowered blood pressure, systemic and pulmonary vascular resistance, and arteriovenous oxygen difference and preservation of preoleic cardiac output were observed in the pGI2 group. In vitro biomechanical tests were performed on aged (group A) and young (group B) porcine intervertebral discs. The timing of micromere production was disturbed in some twinned embryos, but this disturbance was not correlated with subsequent developmental problems. Rural broadcasting rarely receives more than a fraction of total air time, and programs that do exist are uninspiring and ineffective. One group observed a film depicting increasingly more active social interactions between children with positive consequences ensuing in each scene, while a narrative soundtrack emphasized the appropriate behavior of the models. The electromechanical model of the generator is presented and used to predict its electrical performances. Quantitative exercise thallium-201 variables versus cardiac catheterization. Immunostaining with a Na(v)1.5-specific antibody revealed that Na(v)1.5 protein was localized in certain distinct regions of brain including the cerebral cortex, thalamus, hypothalamus, basal ganglia, cerebellum and brain stem. The presented case is of a young male (aged 19 yrs) with a pectus excavatum who showed significant exercise intolerance, despite normal pulmonary function at rest, including carbon monoxide diffusing capacity.

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This two-site study aimed to determine whether olanzapine is superior to placebo in increasing body mass index (BMI) and improving psychological symptoms in out-patients with AN. MRI lesions after invasive therapy of carotid artery stenosis: a risk-modeling analysis. Selected readings in general surgery: An interview with editor-in-chief Lewis Flint, MD, FACS. Cardiac perfusion of fluorescein-conjugated dextran was used to label blood vessels within the eye to serve as an anatomic reference. Applying national models to routinely collected population location data can extend land use modeling techniques to population exposure assessment and to informing surveillance, policy, and regulation.

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Connections and continuities point to possible new transport pathways that could substitute for other modes of traffic. Several health economic models on the cost effectiveness of childhood immunization strategies have been published, and although constrained by missing data, have generally found childhood immunization strategies to be cost-effective. Except for the prolongation of PR interval in two patients while taking verapamil, no side effects from verapamil therapy were observed. The radiological correlate of basic histopathologic findings is being approached with quantitative methods. Angle closure secondary to pupil block is an entity known to occur in aphakic and pseudophakic patients. Systemic vascular dysfunction has been suggested to contribute to glaucomatous damage. Ferdinand von Hebra was the first well-known Austrian dermatologist and he belonged to the so-called IInd Viennese School of Medicine in the 19th century, of which he was one of the most prominent members. After disease remission, the outcome of a subsequent pregnancy becomes a great concern for these women.

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Concurrent chemotherapy and pulsed high-intensity focused ultrasound therapy for the treatment of unresectable pancreatic cancer: initial experiences. Vision of the future: initial experience with intraoperative real-time high-resolution dynamic infrared imaging. The rice gene ELONGATED UPPERMOST INTERNODE1 (EUI1) encodes a P450 monooxygenase that epoxidizes gibberellins (GAs) in a deactivation reaction. Complete discharge communication (defined as written communication of medication list, nutrition plan, and red flag checklist) was relayed to only 45 outpatient cardiologists and to 26 PCPs. The dependence of the rate on the donor-acceptor separation may also be affected in a way of producing low values for the exponential falloff parameter. Genome-wide association studies (GWAS) have identified numerous common SNPs associated with prostate cancer (CaP) risk in men of European descent. A large vascular leiomyoma or an infected sebaceous cyst of the chest?. To determine the mechanisms by which IL-1beta influences lung development, we have generated transgenic mice in which human IL-1beta is expressed in the lung epithelium with a doxycycline-inducible system controlled by the Clara cell secretory protein promoter. Clinical experiences such as the one reported here, in which the clinical formulation of the patient was consistent with known neuroendocrine phenomena and in which the treatment approach was successful, are crucial to developing promising approaches that can be tested in controlled trials.

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Microbial backward mutation test, Ames Salmonella/microsome plate assay, on six bacterial strains (Salmonella typhimurium TA 98, 100, 1535, 1537, 1538 and E. Also taught were basics of market values, social customs, and causes of poverty. A CRAC-like motif in BAX sequence: relationship with protein insertion and pore activity in liposomes. Quantification of cardiac function with multislice spiral CT using retrospective EKG-gating: comparison with MRI. Protective and risk factors associated with adolescent sleep: findings from Australia, Canada, and The Netherlands. We have carried out periodic-DFT calculations of the high temperature face centred cubic phase modelled as the standard structure and also of the low temperature simple cubic phase, the latter for the first time. When the schedule was changed from multiple variable-interval 3-min variable-interval 3-min to multiple variable-interval 3-min extinction in the second and fourth phases of the experiment, overall response rates in the unchanged variable-interval 3-min component increased in two pigeons. It was observed that some of these compounds have the potential to inhibit acetylcholinesterase, whereas others show activity against butyrylcholinesterase, depending on the substitution pattern at the two aromatic rings of these chalcones. We determined whether treatment with Mycobacterium vaccae by gavage influences the host immune response both locally and systemically.

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Our algorithm, segmentation by weighted aggregation, is derived from algebraic multigrid solvers for physical systems, and consists of fine-to-coarse pixel aggregation. Amelioration of prolidase deficiency in fibroblasts using adenovirus mediated gene transfer. Nearly half of participants were found to be depressed at some time over a 10-year period, and most cases across ethnic groups were judged to need further treatment. In 6 patients, steroid levels were measured for 2-7 months after treatment. aureus were obtained on admission and weekly thereafter until discharge or death from 204 consecutive patients admitted to the surgical intensive care unit and liver transplant unit. Two proteins were studied, in water-trehalose matrices: a water-soluble protein (carboxy derivative of horse heart myoglobin) and a membrane protein (reaction centre from Rhodobacter sphaeroides). Effects of lipid peroxidation on structure of human plasma lipoproteins (magnetic resonance spectroscopy).

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Tumor induced neo-angiogenesis was evaluated by alkaline phosphatase staining of the vessels, by using the Tg(fli1:EGFP)y1 strain of Zebrafish and by the quantification of the zebrafish vascular endothelial growth factor and of its receptor. Antibodies, clinical and hematologic findings in immunoneutropenias. Seventy-eight 5 mm silicone sponges were sutured to autopsy eyes using various techniques, and resulting scleral indentation was compared to a control series. Temporal and spatial phases in the development of the Berlin metropolis in the past and the future. The two cases of KS from the same family underwent extensive clinical assessments, with next-generation DNA sequencing and bioinformatics analysis to identify pathogenic genes. Steroid administration significantly modified AST, ALT and PT levels only in patients with chronic liver disease. Five of the 8 patients with myocarditis presented with congestive cardiac failure with 3 of them having no associated hypertension or valvar involvement to account for it. The sensor is responsive to BPA down to femto molar levels, but not to structurally similar compounds including bisphenol F ultram tabs (BPF) or bisphenol S (BPS) even at much higher concentration. Evidence for adenosine triphosphate as an excitatory transmitter in guinea-pig, rabbit and pig urinary bladder. Efforts fall short in general, but considerably more so for some program features than others.

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The present study examined if regional anticoagulation with citrate (RAC) using commercially available solutions can overcome the associated problems of SAH to produce economical benefits. Therefore, it is essential to ensure comprehensive multidisciplinary diabetes education to lower the risk factor of fear of injections. The pathological diagnosis of a biopsy specimen was adenocarcinoma. The onset of variant Creutzfeldt-Jakob disease (vCJD), and the unknown prevalence of infection after the extensive dietary exposure to bovine spongiform encephalopathy (BSE) prions in the UK, has led to renewed interest in kuru. Previously, proteomic analysis revealed that the expression levels of vimentin and serine/threonine protein phosphatase 2A (PP2A) are significantly increased when mice are exposed under continuous light for 7 days compared to a condition of 12 hrs light/dark cycling exposure using retina degeneration 1 (rd1) model. Detailed history, clinical examination, and serological and radiological investigations failed to reveal the cause of the pain in all cases.

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Under the optimization separation conditions with the separation system, more than 41 components in the methanol extract of Ginkgo biloba were resolved. Development of neuron structure of the fascia dentata in the rat. This submission focuses on the workup and treatment of pediatric lymphatic malformations at our institution, with a focus on sclerotherapy. Especially in images with poor count statistics, median filtering after reconstruction with ML-EM is effective as a simple, widely available method. The co-organization of polymerizable imidazolium-based ionic liquids and p-xylene led to the formation of a bicontinuous cubic phase with a primitive-type periodic minimal surface, and for the first time an anion exchange membrane preserving 3D interconnected ionic nano-channels was fabricated through in-phase photopolymerization of bicontinuous cubic liquid crystals. Tribute to Harry Loren Arnold, Jr., on the 25th anniversary of the H.M.J.--1941-1966. During the 6th 5-year plan, the central government took over all aspects of the program.

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The data from these studies therefore suggest that the endocannabinoid system and the CB1 receptors located in the ventral mesencephalon may play an important role in regulating drug reward processes, and that this substrate is recruited whenever dopamine neuron activity is increased. To examine the presentation and management of invasive fungal infections in sarcoidosis patients. We present data from awake, freely moving rats in which a silicone balloon was surgically implanted in the duodenum. We investigated the role of phosphatidyl inositol-3 OH kinase (PI3K)-Akt signaling in the regulation of HIF-1alpha and VEGF expression in human gastric adenocarcinoma. Anticipations and experiences of menopause in a Danish female general population cohort born in 1936. The pamphlet describes the resources and methods of demographics including the creation and use of demographic data products.

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