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Cardiacin (Digoxin)

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Cardiacin is used to treat heart pain (angina) and may be used after a heart attack. Talk to your doctor about the possible risks of using this drug for your condition. Cardiacin comes as a tablet, capsule, or pediatric elixir (liquid) to take by mouth. Cardiacin is usually taken once a day.

Other names for this medication:
Agoxin, Cardiacin, Cardiogoxin, Digacin, Digibind, Digitek, Digobal, Digohan, Digoregen, Digosin, Digossina, Digoxen, Digoxin, Digoxine, Digoxinum, Eudigox, Fargoxin, Halfdigoxin, Lanadicor, Lanibos, Lanicor, Lenoxin, Purgoxin, Sigmaxin, Vidaxil

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Also known as: Digoxin


Cardiacin target is struggle against certain types of fast heartbeats such as atrial fibrillation or fluttering arrhythmia and heart failure. It is also treats angina. This drug can also be used after heart attack. The effectiveness of Cardiacin is in keeping the heart rhythm under control and to make heart work better (regularly and strongly). It is cardiac (or digitalis) glycosides. Generic name of Cardiacin is Digoxin. Cardiacin is also known as Digoxin, Digitalis, Digitek, Lanoxicaps. Brand names of Cardiacin are Lanoxicaps, Cardiacin, Cardoxin, Digitek, Cardiacin Elixir Pediatric.


Usual Adult Dose of Lanoxin for Congestive Heart Failure:

Rapid Digitalization with a Loading Dose: Peak digoxin body stores of 8 to 12 mcg/kg generally provide a therapeutic effect with minimum risk of toxicity in most patients with heart failure and normal sinus rhythm. The loading dose should be administered in several fractions, with approximately half the total given as the first dose. Additional fractions of the total dose may be given at 6 to 8 hour intervals. Careful assessment of the patient's clinical response should be considered before each additional dose. If the patient's response necessitates a change from the calculated loading dose of digoxin, then calculation of the maintenance dose should be based upon the amount actually given. Tablets: Initial: 500 to 750 mcg usually produces a detectable effect in 0.5 to 2 hours with a maximal effect in 2 to 6 hours. Additional doses of 125 to 375 mcg may be given at 6 to 8 hour intervals until clinical evidence of an adequate effect is noted. The usual amount of digoxin tablets that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 750 to 1250 mcg. Injection: Initial: 400 to 600 mcg of digoxin intravenously usually produces a detectable effect in 5 to 30 minutes with a maximal effect in 1 to 4 hours. Additional doses of 100 to 300 mcg may be given cautiously at 6 to 8 hour intervals until clinical evidence of an adequate effect is noted. The usual amount of digoxin injection that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 600 to 1000 mcg. The injectable route is frequently used to achieve rapid digitalization, with conversion to digoxin tablets for maintenance therapy. Maintenance Dose: The doses of digoxin tablets used in controlled trials in patients with heart failure have ranged from 125 to 500 mcg once daily. In these studies, the digoxin dose has been generally titrated according to the patient's age, lean body weight, and renal function. Therapy is generally initiated at a dose of 250 mcg once daily in patients under age 70 with good renal function.

Usual Adult Dose for Atrial Fibrillation:

Peak digoxin body stores larger than the 8 to 12 mcg/kg required for most patients with heart failure and normal sinus rhythm have been used for control of ventricular rate in patients with atrial fibrillation. Doses of digoxin used for the treatment of chronic atrial fibrillation should be titrated to the minimum dose that achieves the desired ventricular rate control without causing undesirable side effects.

Detailed Lanoxin dosage information


If you overdose Cardiacin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Cardiacin overdosage: confusion, irregular heartbeats, nausea, seizures, vomiting, extremely fast or slow heartbeats, hallucinations, tiredness, problems with vision, diarrhea, lack of appetite.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Lanoxin dosage information

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Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of digoxin injection in the elderly. However, elderly patients are more likely to have age-related kidney or heart problems which may require caution and an adjustment in the dose for patients receiving digoxin injection.

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The loss of symptoms started after 4 months (2-7) and they became completely symptomless after 7-10 months. There were, however, obvious differences between the enzymes in terms of substrate specificity. Anti-estrogens lacking agonist activity suppress invasiveness as well as growth of the breast cancer cells. Spectrophotometric determination of some phenothiazine drugs using 3-methylbenzothiazolin-2-one hydrazone. This study compared the effectiveness and safety of pimozide and chlorpromazine in the maintenance therapy of chronic schizophrenic outpatients.

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We examined the role of the Src kinase Lyn in phospholipase C-gamma 2 (PLC-gamma 2) and phosphatidylinositol (PI) 3-kinase activation in erythropoietin (Epo)-stimulated FDC-P1 cells transfected with a wild type (WT) Epo-receptor (Epo-R). Stability of proteins: temperature, pressure and the role of the solvent. The F3/contactin deficient mice display a severe ataxia correlated with defects in axonal and dendritic projections in the cerebellum. The CH3 domain of CBP binds numerous transcription factors and several viral oncoproteins. Factors that affect the quality of clinical decisions of multidisciplinary cancer teams (MDTs) are not well understood. Correct placement of the electrode was confirmed by intraoperative stimulation. Spontaneous heterotropic pregnancy in sickle cell disease with survival of the abdominal pregnancy. In all patients, biopsy of the jejunum or rectal mucosa, or both, showed moderate to severe damage, irregular atrophy of surface epithelium, and subnuclear vacuolization of crypt epithelium. However, fertilization is costly and causes environmental pollution. The day and time of decision, the indication and outcome of the code, the mode of anaesthesia used, and the condition of the baby at birth were recorded for time interval calculations.

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Cardiolipin drives cytochrome c proapoptotic and antiapoptotic actions. Drugs may interact with a transporter as a substrate and/or an inhibitor. However, such dependencies were not found, and it was possible to describe molecular-level performance with simple Markov chain models. A possible role for tau-actin interaction in neurite outgrowth is postulated. Uncertainties in expected comprehension rates are largely due to imprecision in reader ability and not inaccuracies in text readabilities.

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The trend in Czechoslovakia for people to want to form independent households and not to continue to live in an extended family situation is analyzed. Furthermore, there was an open laceration of the frontal sinus and maxillo-facial fractures. Cerebral blood flow increased proportionally to extracorporeal circulation flow. The tradition to end a meal with fruit may thus have other oral effects than hitherto considered. We experienced an adult patient with Henoch-Schoenlein purpura (HSP) nephritis associated with a postbulbar duodenal ulcer. Studies using a brain index for pre-attentive change detection, the mismatch negativity (MMN), suggested distinct neuronal populations for signaling changes in sound duration and frequency. To evaluate the efficacy and toxicity of irinotecan in patients with metastatic platinum-resistant or platinum-refractory epithelial ovarian cancer or primary peritoneal cancer.

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The additive effects between curcumin and genistein not only support the hypothesis that multiple mechanisms are involved in the action of CFTR potentiators, but also pose pharmaceutical implications in the development of drugs for CF pharmacotherapy. In this paper we investigate the temporal evolution of the static properties of a granular medium by studying the aging over time of the maximum stability angle of submillimetric glass beads. Diacylglycerol-dependent signaling plays an important role in signal transduction through T- and B-lymphocyte antigen receptors. A functional and cell biological analysis of Kre5p was conducted to further elucidate the role of this diverged protein glucosyltransferase-like protein in beta-1,6-glucan synthesis. Pre-treatment staging of prostate cancer: recent advances and future prospects. Physicians and the medical care system play a significant role in reinforcing somatization by patients.

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This study aims to critically review the studies based on such transition models, analyzing their contributions and limitations for health research in Brazilian cities. Atopy was demonstrated in 33 of the 38 asthmatic patients with antibodies. somites, prevertebral elements, neural tube and dorsal spinal ganglia) expression is also seen in tissues with no obvious segmental origin. The tendency of resistant cells to grow closely together suggests the possibility of inter-cell communication for the TNF resistant state. Placental tissue also synthesized substantial concentrations of progesterone from the prohormone pregnenolone. Knowledge about the extent to which assessments of provider efficiency depend on the outcome measure used is an important step toward improved and more equitable comparisons across providers. We examined the ability of alpha-TOS to induce cytostasis and/or apoptosis in two human osteosarcoma cell lines, which carry wild-type pRb but differ in the p53 status. Although this approach is not optimal, a great deal of valuable information can be generated from these specimens. Nanochemistry has advantageous roles to overcome these problems by defining new nanostructures of electrode materials.

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Subjects were divided into four groups, with two durations of the keylight (30 or 120 sec) and either one or four successive colors on the response key preceding food delivery. Twenty-eight patients (20 male, 8 female) were enrolled: 20 diagnosed with lung cancer and 8 diagnosed with benign diseases. FUT3 gene polymorphism associated with Lewis blood group in Chinese Zhejiang population. Animal Vivarium and Department of Ophthalmology, Naval Medical Center, San Diego, California, USA. Our results demonstrate that significant differences in mucus biochemistry and numbers of L.

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Analysis of the isoform selectivity of the compounds used implicates HDAC1 and/or HDAC2 as likely targets for the observed correction, although other HDACs may also play a role. The aim of this study was to explore a behavior-analytic model of analogical reasoning, defined as the discrimination of formal similarity via equivalence-equivalence responding. In comparison, relatively little work has been done examining the physical requirements of preimplantation embryos and the role culture platforms or devices can play in influencing embryo development. However class of medication flagyl , subtotal excision and adequate spinal decompression followed by radiotherapy provide satisfactory results. Apart from improving the image quality of the primary cross-sectional slices, MS-CT significantly enhances two- and three-dimensional image reconstructions. The CMAP suggests that the source of the oscillations results from the opposing effects of Rho activation leading to a decreased level of myosin light chain phosphatase and a cyclic calcium influx caused by increased membrane tension and leading to a periodically enhanced activation of myosin light chain kinase. We found that high titers of Ab anti-GPI mucins, but not anti-GIPLs, were detected in sera from wild-type as well as in TAP1(-/-), CD1d(-/-), and MHC class II(-/-) mice after immunization. One such debate focused on the use of regional chemotherapy after potentially curative resection of hepatic metastases from colorectal cancer. For a particular theory, we will test the validity of such a model for small variations in voltage and strain about the resting state of outer hair cells. However, prostate cancer is unique compared to other cancers because, despite a high prevalence, some men choose watchful waiting or no treatment, especially if they are older and/or have a well-differentiated tumor.

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In conclusion, we have demonstrated that the activities of PAF-synthesizing enzymes are activated soon after the induction of LTP and that this effect is linked to the activation of NMDA-receptors. Expression profile of the RNA-binding protein gene hermes during chicken embryonic development. In summary, high doses of tamoxifen were required in the nude mouse to obtain clinically relevant serum concentrations, and significant tumor levels were achieved at doses that resulted in undetectable serum levels. Plasma glucose levels did not change, but FFA levels decreased significantly upon asphyxia with a concomitant increase in plasma noradrenaline levels. Three focus groups and two semistructured interviews were conducted with people at higher neurontin medication dosage used risk of IMD in Hunter New England Local Health District in New South Wales. cepacia complex infection who attended the Belfast City Hospital between January 1997 and November 1998. Nail fold capillaroscopy differs widely between systemic sclerosis and chronic graft vs host disease of the skin. Computed tomography (CT) displayed a mass around the iliac vessels while physical, laboratory, and other imaging examination did not show any other tumor. In the Madin-Darby canine kidney cell (MDCK) model, rosiglitazone inhibited cyst growth in a time- and dose-dependent manner and this was accompanied by a reduction in basal proliferation and an increase in apoptosis. These regulations constitute a basic guideline to be followed by all physicians.

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Correlational analyses support the construct validity of the ASC, especially the panic-fear factor. This study found out that attribution of blame and the coping variable affect functioning depending on the level of victimization. In response to treatment, the level of IAPs was not altered in a way that explained the differences in cellular chemo- and radiosensitivity. Children with FASD and PAE have extensive needs and should receive individualized recommendations. Loss of E-cadherin mediated cell-cell adhesion as an early trigger of apoptosis induced by photodynamic treatment. Body image quality of life was affected not only by specific pathologies related to body image disturbances, but also by other psychopathological syndromes. Over 6.5 million animals were slaughtered and disposed of, over 4 million as a direct result of disease and a further 2.5 million on welfare grounds.

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We studied a patient who had persistent bitemporal throbbing headache with the associated findings of high-altitude headache syndrome 15 years after a compression chamber accident. The RAS group significantly improved performance on the DGI and several secondary measures, and they maintained improvements for the DGI, Tinetti, FOGQ, and balance and gait items of the UPDRS above pretraining values at least 4 weeks after practice termination. However, the general tasks group had higher grip strength than the repetitive tasks group, demonstrating differences according to job specificity. Choice proportions for large reward increased with increases in delay intervals programmed on fixed-interval schedules and supported the predictions derived from a general choice model originally formulated by Fantino and later developed by Navarick and Fantino. Anatomo-histological structure of the sympatic nervous system in the esophagus and the rectum of the nematode Ascardia galli (Schrank, 1788). These results suggest that the acute effects of Acarbose on glucose tolerance can be explained on the basis of its ability to alter intestinal nutrient absorption. Genomic deletions in cell lines derived from primitive neuroectodermal tumors of the central nervous system. This study presents measures of common behavioral objectives for weight management interventions. 6-(2-Dimethylaminonaphthoyl) alanine (DANA) was prepared via an enantioselective synthesis and incorporated into the S-peptide of RNase S establishing the large changes in fluorescence that can occur upon peptide-protein interaction. Protective efficacy of a modified immune serum globulin in experimental group B streptococcal infection.

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Patients with an onset of alcoholism before their 20th birthday were found to have a significantly higher incidence of paternal alcoholism and were twice as likely to have been incarcerated for crimes involving physical violence. Standard New Jersey light traps were operated on 12 reservations throughout the summer seasons in 1984 and 1985. Castrating operations associated with metastatic lesions of the breast. Effects of IC14, an anti-CD14 antibody, on coagulation and fibrinolysis during low-grade endotoxemia in humans. We contrasted the miRNA content of first year crop plants with that of second year crop ones, and were able to show that of 89 conserved (belonging to 25 families) and six novel miRNAs (six families), 29 of the former and three of the latter were differentially expressed. Flail chest is a common injury sustained by patients who experience high-energy blunt chest trauma and results in severe respiratory compromise because of altered mechanics of respiration. P300 amplitude in subjects with primary insomnia is modulated by their sleep quality.

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Placement of internal ureteral stents before extracorporeal shock wave lithotripsy of large stone burdens has decreased the incidence of post-extracorporeal shock wave lithotripsy colic, secondary endoscopic procedures and prolonged hospital stays. Preliminary results on the effects of pretreatment with thymic extract on experimental endotoxin hepatitis in the mouse. We used Poisson regression to acticin determine the association between painful body regions identified preoperatively and both WOMAC pain at follow-up and improvement in pain as defined by the minimal clinically important difference (MCID). Effect of pamidronate on the stimulation of macrophage TNF-alpha release by ultra-high-molecular-weight polyethylene particles: a role for apoptosis. Synthesis and structural analysis of the anilides of glucuronic acid and orientation of the groups on the carbohydrate scaffolding. Treatment with the combination of captopril plus HCTZ for one day lowered MABP to the same extent as captopril alone, but produced a synergistic 44 mm Hg MABP lowering after the second day combination treatment.

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Anesthesia of the heart patients submitted to surgery not related to the heart disease. Intraductal papillary mucinous tumor with pancreatobiliary and pancreatodigestive fistulae: a case report. Although the results of several studies consistently report higher occurrence of diabetes among disadvantaged groups in adult populations, rather sparse and contradictory findings have been reported for the young. Horse rug lung: toxic pneumonitis due to fluorocarbon inhalation. Acetoacetate, 3-hydroxybutyrate, lactate, pyruvate and alpha-ketoglutarate in the blood in chronic uremia patients treated with periodic hemodialysis. These features of early development indicate a regionalization of the Neoceratodus vertebral column: the cranial rib marks the boundary between the cervical and thoracic regions, the two more anterior vertebrae lacking ribs represent the cervical region, while somites 1-4 (cranial half), lacking any vertebral development, represent the occipital region. We concluded that CY-sensitive host regulatory cells restricted the expression of adoptive tumor rejection immunity. The purpose of this study is to determine the effect of ED gene transfer into lung cancer cells on in vivo tumor growth in a murine model.

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The synthesis and SAR of 5-heterocycle-substituted aminothiazole adenosine receptor antagonists is described. These assessments demonstrate that the availability of alcohol, measured by the number and types of alcohol outlets, is related to violence. The dependence of the ingress and the egress processes on the relative size of the macromolecule to the pore size was determined. Repeated distraction osteogenesis for excessive vertical alveolar augmentation: a case report. Pharmacology- can you take two 10 mg zyrtec a day biochemistry and physiopathology of tardive dyskinesia: review of the latest findings and controversies. Central (intracerebroventricular) or peripheral (i.p.) administration of CRF or Ucns inhibits gastric emptying and promotes colonic motility. Our results showed that the PSA G/G genotype is associated with a greater Gleason score and serum PSA level but lower serum testosterone level and could be considered a risk factor for a poor outcome of PCa. grandiflora subfamilies showing a considerable divergence from V. 5) Taken together, it was suggested that the enteric-coated lactoferrin (LF) might promote the secretory function of lacrimal gland cells in aged rat, resulting in the formation of numerous B granules. Significant differences were observed in age at presentation, stage, histopathology and extent of bone marrow involvement between the groups.

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DRESS syndrome is a hypersensitivity reaction which is due to massive T cell stimulation resulting in cytotoxicity and eosinophil activation and recruitment. Positive cells were counted and presented as a percentage of positive cells. Beware misleading cues: perceptual similarity modulates the N2/P3 complex. Identifying gestational diabetes mellitus and the effect of different diagnostic criteria. Numerical abnormalities of chromosomes 17 and 18 were relatively common findings in patients with colorectal cancer, with chromosome 17 being associated with a higher incidence of tumors localized to the rectum and a worse clinical outcome. The affinity of the label for the reversible binding site in the three enzymes follows the order Zn greater than Cd greater than Co. As presented here, the use of enzyme labels to measure two (or more) haptens simultaneously represents a significant advance in the use of immunoassay techniques. Qualitative evaluations of signal intensity, tumor conspicuity, definition of tumor margin, distinction between solid and cystic-like parts within tumor, and calcification were performed. Comparative study of electroencephalographic, transcorticographic, and straticorticographic results. To date, the molecular pathways controlling apoptosis are poorly understood in Lepidoptera.

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Thus, the balance between the HA and NA activities is critical for influenza virus replication in a different host system. The resealed ghosts have been characterized with cyproheptadine 2mg/5ml syrup respect to their shape, size, stability in culture and their hemoglobin and ATP contents. A subsequent, smaller, oral inoculum of 20 larvae provoked an eosinophil response similar to that of the first experiment. There is a need to improve our diagnostic skills and knowledge of possible errors and establish better communication with neurosurgeons. coli harboring appY plasmids produced 2.8 mg lycopene/g dry cell weight (DCW), the same amount obtained with dxs despite the fact that appY is not directly involved in the lycopene synthesis pathway.

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Zelenin and his role in the development of clinical electrocardiography and functional diagnosis. The subsequent histopathological examination revealed that this tumor was an adenosarcoma. Bacteremia is a frequent complication found in HIV-infected patients and is usually associated with a poor prognosis. Constructs and surnatants were collected and analysed at 1, 3, 7, 14 and 21 days after seeding. The aim of this study was to evaluate differences in gallbladder contractility by measuring gallbladder wall thickness, fasting and residual gallbladder volume, and gallbladder ejection fraction in patients with cirrhotic and malignant ascites. In our simulations, membrane fusion progresses through an inverted micelle fusion intermediate before reaching the hemifused state. The observation of falsely low concentrations of LDL-C and artifactural undetectable HDL-C might result in the mismanagement of patients of multiple myeloma with monoclonal gammapathy, because the LDL-C and HDL-C concentrations are positive and negative risk factors of cardiovascular diseases. It is also contraindicated in women who have a blood disease, use anticoagulants, or have AIDS. Prostate cancer (PCa), a disease, is characterized by abnormal cell growth in the prostate - a gland in the male reproductive system. Although a preference to operate multiple vessel disease with classical cardiopulmonary bypass (CPB) has to be considered, the present study shows evidence for a different pattern of early decline and late recovery of cognitive functions in patients undergoing CABG with and without CPB. nolvadex dosage after anavar cycle

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Here, we show that RNAi-mediated knockdown of the SMC5/6 complex components in human cells increases the efficiency of gene targeting due to a specific requirement for hSMC5/6 in sister chromatid HR. Effect of dietary vitamin E on the activities of the glutathione peroxidase system in rat tissues. The author suggests that a number of changes need to be made in the assumptions usually employed when analyzing migration in capitalist countries. It is proposed that proton displacement due to the interaction between humic substances and the oxide, along with the formation of ternary complexes with the Pb(II) cation bridging the oxide and the humic substances (Type A complexes), cause the deviation from additivity. In the present study, we measured serial changes in myocardial creatine kinase and creatine kinase-MB activities after acute occlusion of the left anterior descending (LAD) coronary artery in 20 open-chest pentobarbital-anesthetized dogs.

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