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Calotec (Calcitriol)
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Calotec

Calotec is the active form of vitamin D, normally made in the kidney. It is also known as 1,25-dihydroxycholecalciferol. It is a hormone which binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes.

Other names for this medication:
Actical, Alfacip, Alphadol, Arachitol, Arcium, Biocal, Calasto, Calbovic, Calcikind, Calcit, Caldix, Calosto, Caltop, Calzem, Dmcal, Estovon, Fovit, Koncal, Laretol, Novadee, Osteobel, Ostonex, Politrol, Primacal, Rical, Riecal, Rolsical, Solbiocal, Tobalt, Trolec

Similar Products:
Celexa, Tricor, Imovane, Claritin, Xalatan, Sumycin

Also known as: Calcitriol

Description

Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are available in the foods that you eat. Vitamin D is necessary for strong bones and teeth.

Lack of vitamin D may lead to a condition called rickets, especially in children, in which bones and teeth are weak. In adults it may cause a condition called osteomalacia, in which calcium is lost from bones so that they become weak. Your doctor may treat these problems by prescribing vitamin D for you. Vitamin D is also sometimes used to treat other diseases in which calcium is not used properly by the body.

Ergocalciferol is the form of vitamin D used in vitamin supplements.

Some conditions may increase your need for vitamin D. These include:

Alcoholism Intestine diseases Kidney disease Liver disease Overactivity of the parathyroid glands with kidney failure Pancreas disease Surgical removal of stomach

In addition, individuals and breast-fed infants who lack exposure to sunlight, as well as dark-skinned individuals, may be more likely to have a vitamin D deficiency. Increased need for vitamin D should be determined by your health care professional.

Alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are forms of vitamin D used to treat hypocalcemia (not enough calcium in the blood). Alfacalcidol, calcifediol, and calcitriol are also used to treat certain types of bone disease that may occur with kidney disease in patients who are undergoing kidney dialysis.

Claims that vitamin D is effective for treatment of arthritis and prevention of nearsightedness or nerve problems have not been proven. Some psoriasis patients may benefit from vitamin D supplements; however, controlled studies have not been performed.

Injectable vitamin D is given by or under the supervision of a health care professional. Some strengths of ergocalciferol and all strengths of alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are available only with your doctor's prescription. Other strengths of ergocalciferol are available without a prescription. However, it may be a good idea to check with your health care professional before taking vitamin D on your own. Taking large amounts over long periods may cause serious unwanted effects.

Dosage

Generic Calotec is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Calotec suddenly.

Overdose

If you overdose Generic Calotec and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Calotec are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is especially important that you receive the right amounts of vitamins so that your baby will also get the vitamins needed to grow properly. Infants who are totally breast-fed and have little exposure to the sun may require vitamin D supplementation. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Only small amounts of alfacalcidol, calcifediol, calcitriol, or dihydrotachysterol pass into breast milk and these amounts have not been reported to cause problems in nursing babies.

It is not known whether doxercalciferol or paricalcitol passes into breast milk. Be sure you have discussed the risks and benefits of the supplement with your doctor.

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The study included 70 consecutive patients who underwent vestibular evaluation before and after cochlear implantation. Parents generally rated the family-centred behaviours of staff as positive. Additionally, lower BMI was associated with better recovery during sleep, expressed by a greater amount and magnitude of recovery reactions, which suggests that PA in the long term resulting in improved fitness has a positive effect on recovery, even though high PA may disturb recovery during the following night. There was no association between IRU in the navicular bone and MR lesions of either the DSIL origin or the CSL insertion, however there was an association between IRU in the navicular bone and combined lesions of the CSL, DSIL and navicular bursa. Modification of the cell surface expression of histocompatibility antigens induced by the neurotoxin 2,5 hexanedione. But the mortality rates of residents injury, poisoning and malignant neoplasm diseases in the soaked area and the collapsed area were higher than those of non-flood area. Breastfeeding practices were suboptimal and differed by ethnicity, which suggests need for tailored interventions at multiple levels to address ethnic-specific challenges and norms. The diagnosis of RLS/WED relies on clinical criteria, and the only instrumental tool, the suggested immobilization test, may lead to equivocal results. Chinese experimental minipigs underwent placement of a left circumflex artery aneroid constrictor.

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Clustering of FH, hormonal abnormalities, and high hs-CRP is associated with MES in Chinese middle-aged men. Development of a single-step immunoassay microdevice based on a graphene oxide-containing hydrogel possessing fluorescence quenching and size separation functions. Whereas the overexpression of rootletin results in the formation of extensive fibers, small interfering RNA-mediated depletion of either rootletin or C-Nap1 causes centrosome splitting, suggesting that both proteins contribute to maintaining centrosome cohesion. Molecular basis for the influence of muscle length on myocardial performance. We analyzed trace metals in frozen brain tissue of several subcortical nuclei from 3 patients with primary adult-onset dystonia and 10 control subjects. CLINICAL TRIALS WITH THE NEW SALIDIURETIC, BRINALDIX, IN THE TREATMENT OF EDEMA. Self-reported symptoms of anxiety and depression were analyzed with latent class analysis. Treatment with vitamin B complex (neurobion) and thiamine exerted a positive effect. Recent studies using genetic mouse models revealed that perivascular stromal cells function as mesenchymal stem cells, and their differentiation status may vary during the early stage of life to adulthood.

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The effect of sodium chloride baths on the physical work capacity and extrasystole of patients with ischemic heart disease and stable stenocardia. The mitotherapy strategy offers a new potential therapeutic approach for treating NAFLD. To evaluate blood pressure (BP) control, factors associated with poor BP control, target organ damage (TOD), white-coat hypertension, treatment-resistant hypertension and secondary hypertension in patients referred to a tertiary-level hypertension clinic. Among catalytic antibodies, the well-characterized antibody 43C9 is unique in its ability to catalyze the difficult, but desirable, reaction of selective amide hydrolysis. We suggest the Ov-SPI proteins play a vital role in nematode molting by controlling the activity of an endogenous serine protease(s). Evaluating Strategies For Reducing Health Disparities By Addressing The Social Determinants Of Health. The embolization procedure was technically straightforward and relatively safe. Virus resistant cell lines: A paradigm shift in risk mitigation. The medically successful intervention was accomplished by the publication of scientific enquiry and by attention to the culture of Aborigines.

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Endoscopic obliteration of esophageal varices with Bucrylate: an interesting technic, but with too many disadvantages. However, this study stressed the need to perform MRI prior to operation to document any associated neuraxial abnormality in clinically asymptomatic AIS patients. In the early-weaning program, calves were fed a highly palatable pre-starter diet from 3 d of age until they consumed 227 g/d, and then fed a mixture of pre-starter (227 g) and starter diet ad libitum. The first meeting focused on conceptualization and identification of themes related to IPT meetings that are important to patients. Infants who were born vaginally had significantly higher plasma resistin levels, suggesting that this hormone might also be associated with stress or inflammation induced by the birth process. Emerging evidences suggests that a number of differentially expressed lncRNAs are involved in tumorigenesis. This study aimed to establish a method for the selective amplification of cell-free fetal DNA (cffDNA) in maternal plasma and preserve the integrity of DNA fragments during amplification, thereby providing a sufficient amount of cffDNA to meet the requirement of routine non-invasive prenatal testing. Multichannel EEG was recorded to study the gamma-band (30-70 Hz) activity phase-locked to visual checkerboard stimulus onset, in grand-average data of 10 subjects and in three additional individuals.

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Induction of apoptosis by N-(4-hydroxyphenyl)retinamide in glioma cells. We find that transformation with E1A and Ras actually reverses the chemosensitivity/transcriptional differences between WT p53 and S47. This review may seem too complex, but proper attention to many small details means the difference between success and failure, or at least between large and small morbidity. Such transformations are significant in the transportation and cycling of elements in the environment. The re-endothelialized area was significantly greater in the CBD-HGF- treated rats than in the control or HGF -treated rats. High frequency of de novo deletions in Mexican Duchenne and Becker muscular dystrophy patients. Author response: The clinical spectrum of Caspr2 antibody-associated disease.

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The optically active C13-fragment was synthesized asymmetrically by using the Wittig reaction from chiral synton for comparison with the natural fragment. A variety of stressful events can trigger the production of free radicals by exposed cells. In children with markedly abnormal brain anatomy, multichannel VEP recordings can provide quantifiable measures of visual pathway function detected in atypical locations. Oxygen can be given to verify the integrity of the monitoring technique and check any abnormal reading. Studies published to date, however, are far from consistent with regard to the morphologic changes reported following H. Maternal, household, and healthcare system factors contributed to child mortality in Nigeria. To explore a possible role for PMNs in the tissue damage of human myocardial infarction, we investigated localization of intercellular adhesion molecule-1 (ICAM-1) and CD66b (previously clustered as CD67), a marker of degranulation of human PMNs, in relation to deposition of complement in tissue specimens of infarcted and healthy parts of the heart obtained from 20 patients, who had died following acute myocardial infarction. In the case of caffeine, the ratio paraxanthine/caffeine did not differ between morbid obese and healthy individuals.

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Immune responses of cattle to experimental anti-Fasciola hepatica vaccines. Substance P, adrenaline and glutamate neurons originating from the rostral ventrolateral medulla oblongata (VLM) produce a tonic excitation of sympathetic preganglionic neurons. An investigation of dietary nutrition in kindergartens of Chongqing, China. The influence of intrathecally (it), intracerebroventricularly (icv) and intraplantarly (ipl) administered MK-801 co-injected with JNJ7777120 administered intraperitoneally (ip) was determined in the modified Randall-Selitto paw pressure, the tail flick and plantar tests. The ability of the kidneys to remove excess intravascular volume is decreased in a substantial amount of euvolemic and optimally treated HFrEF patients.

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Effect of binaural freeing from masking is reflected in these same components of long-latency auditory EPs in perception of spatially translocating signals. Hemopexin (HPX) has been levaquin 500 mg twice daily identified as an anti-inflammatory agent, but its role in endotoxemia is unclear. IM residency programs for their perspectives on which Core EPAs new interns must or should possess on day 1, which are most essential, and which have the largest gap between expected and observed performance. Assessment of an LC-MS method for plasma quantification of the new immunosuppressant FK778 through comparison with HPLC-UV. Two serotonin antagonists, methysergide and ketanserin, were examined for their ability to interfere with jejunal pathology comprising the influx of mucosal mast cells and other inflammatory cells during an infection with T. It is important to recognize this rare complication of pneumoreduction and promptly treat the ensuing tension pneumoperitoneum. In a retrospective review of 724 lesions that underwent sonographically guided core biopsy of nonpalpable breast lesions, 62 cases had a diagnosis of focal fibrosis.

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One basic region, two helix regions and one loop region were found to be conserved in wheat bHLH TFs. In the present study, we use specific inhibitors and activators to elucidate the signal transduction pathways involved in this process. Thus, maternal diabetes was important in predicting body size in the offspring even after accounting for the effects of the birth weight and maternal body size. Role of fascin in the proliferation and invasiveness of esophageal carcinoma cells. Consequences of the condition may include preterm birth and pelvic inflammatory disease (PID). These findings provide evidence that the optimised method can be used in human clinical samples of low bacterial biomass such as the investigation of the skin microbiota. Although many interesting ideas have been proposed to clarify their mode of action, no single hypothesis adequately explains their many molecular interactions and responses. Additional multilevel models were used to compare aspects of QoL between dementia subtypes. Critical analysis of the method of screening congenital hypothyroidism in France.

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Following a worry induction, older and younger adults endorsed a wide variety of negative affect beyond the typical emotions associated with worry. Understanding the pathogenesis of osteoporosis requires the genetic characterization of the relationship among multiple gene variants, the encoded proteins, and the environmental mediators vs tenormin medicine bone physiology. 5-9 years follow-up results following 26 out of 37 operated injuries of the ligaments of the knee are reported. In addition, one of the mutants formed more root nodules than the wild type. Accuracy of intraocular pressure measurement using a noncontact Keeler tonometer.

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To quantify the precision of mapping from retinotopic (retina-centered) to spatiotopic (world-centered) coordinates in blind humans implanted with a retinal prosthesis device. Additionally, in opposition to the function of the Schottky junction, injection of hot electrons from plasmonic Pt into PCN-224(M) would lower the electron density of the Pt surface, which thus is tailorable for the optimized catalytic performance via the competition between the Schottky junction and the plasmonic effect by altering the light intensity. In these programs emphasize early recognition, early telephone contact with the EMS system, and early defibrillation. Histometric analysis of white pulp arterial vessels in congestive splenomegaly. This review attempts to provide an overview of risk factors and epidemiology of emerging resistant bacterial infections and their management in HSCT recipients. None of 12 evaluable patients with brain metastases responded to intracarotid VP-16 although 5 had no immediate tumor progression from 1-4 months. This study investigated the relationship between reproductive events during adolescence and subsequent breast cancer risk.

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