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Calgel (Calcitriol)
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Calgel

Calgel is a hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give Calgel.

Other names for this medication:
Actical, Admax, Alfacal, Alfacalcirol, Alfacip, Arachitol, Arcium, Biocal, Biocitral, Bonetuf, Calcicare, Calcitriol, Calday, Caldikind, Calfa, Calosto, Calsonic, Caltop, Calvical, Calzem, Dmcal, Laretol, Minroset, Nutribone, Ostonex, Politrol, Primacal, Qpcal, Refirm, Rical, Rolsical, Romical, Sorvate, Tobalt, Vezocal, Zaxial

Similar Products:
Provigil, Glyburide, Atarax, Imitrex, Starlix, Epivir, Lozol, Tofranil, Arcoxia, Bystolic

Also known as: Calcitriol

Description

Generic Calgel is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Calgel are intestine and bone. Generic Calgel receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Calgel may also act on the kidney and the parathyroid glands. Generic Calgel is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Calgel has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Calgel, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Calgel in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Calgel produces other independent beneficial effects. Calgel is also known as Calcitriol. Generic Calgel treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Calgel is Calcitriol. Brand name of Generic Calgel is Calgel.

Dosage

Generic Calgel is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Calgel suddenly.

Overdose

If you overdose Generic Calgel and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Calgel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Calgel if you are allergic to Generic Calgel components. Do not take Generic Calgel if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Be careful with Generic Calgel if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries). Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. It can be dangerous to stop Generic Calgel taking suddenly.

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When a single bolus injection of non-diffusable indicator is intravenously performed, the time density curve of a cerebral tissue consists of the following two components: the time density curve of a carotid artery (g(x)) and the dispersion curve through the cerebral tissue (f(x)). Voltage clamp characterization of a calcium-dependent chloride conductance in a putative invertebrate motoneuron. I: Low pH-induced rearrangement in spike protein quaternary structure precedes virus penetration into cells. Effect of a Trichinella spiralis infection on the distribution of mast cell precursors in tissues of thymus-bearing and non-thymus-bearing (nude) mice determined by an in vitro assay. This review provides a comprehensive overview of how the microbiota and microbiota-derived products influence both the mucosal and systemic immune system of fish. The overall structures of both forms are similar to those of bovine low molecular weight protein-tyrosine phosphatase and arsenate reductase from Staphylococcus aureus.

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Effects of Smoking and Smoking Cessation during Pregnancy on Adverse Birth Outcomes in Rhode Island, 2012-2014. The Analysis of Characteristics in Dry and Wet Environments of Silicon Nanowire-Biosensor. A novel benzimidazole and other constituents with antiproliferative and antioxidant properties from Thymelaea microphylla Coss. All serovars within serogroups Pyrogenes (kwale, mombe and a strain closely related to serovar nigeria), Hebdomadis (marondera and mhou), Tarassovi (ngavi) and Sejroe (balcanica and hardjo) were L. Using a newly developed interview instrument, the Levine Denial of Illness Scale (LDIS), the level and modes of denial were assessed in 45 male patients who were hospitalized for myocardial infarction or for coronary bypass surgery, of whom 30 were followed for 1 year after discharge.

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