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Calcimet (Calcitriol)
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Calcimet

Calcimet is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis. Systemic Calcimet is FDA indicated to control hypocalcemia in patients on chronic renal dialysis, secondary hyperparathyroidism in those with chronic kidney disease not yet on dialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.

Other names for this medication:
Actical, Alcee, Alphadol, Apcical, Aristrol, Biocal, Biocitral, Bonetuf, Calbovic, Calcicare, Calcigra, Calcikind, Calcimet, Calcit, Calcitriol, Calcor, Calday, Calsure, Caltop, Calvical, Calzem, Citroj, Coecoral, Devita, Dmcal, Koncal, Kurecal, Laretol, Nutribone, Rical, Ritoca, Romical, Statbone, Sunmic, Trolec, Vitalpha

Similar Products:
Exelon, Buspar, Phenergan, Rocaltrol, Calan, Periactin, Elocon

Also known as: Calcitriol

Description

Generic Calcimet is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Calcimet are intestine and bone. Generic Calcimet receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Calcimet may also act on the kidney and the parathyroid glands. Generic Calcimet is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Calcimet has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Calcimet, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Calcimet in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Calcimet produces other independent beneficial effects. Calcimet is also known as Calcitriol. Generic Calcimet treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Calcimet is Calcitriol. Brand name of Generic Calcimet is Calcimet.

Dosage

This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Rocaltrol. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Calcimet and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Calcimet are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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There is no difference in the mean induction to abortion interval. Effect of melatonin sleep disturbance in a case with periodic ACTH-ADH discharge syndrome. An integrated view of quantitative trait variation using tomato interspecific introgression lines. The impact of these combined factors on the rheologic behavior of sickle cell suspensions and on guidelines for transfusion has not been explored fully. Conversely, alpha-ketoglutarate (alpha-KG) inhibits this nuclear translocation. Successful treatment of chronic skin diseases with clobetasol propionate and a hydrocolloid occlusive dressing. The details of the cultural develop ment in Eastern North America are unique, but the general trend may be regarded as a common one in human society, and the patterns of can you take zyrtec with cold and flu tablets behavior, as analogous to those developed by other peoples in other areas of the Old World and the New.

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To determine risk factors to intestinal helminthiasis among children aged 1-15 years in Gwagwalada, Nigeria. However, intermediate (damage) and long-term (mortality) outcomes appear not to be influenced by the type of disease onset in SLE. Occupation of alphavbeta3-integrin by endogenous ligands modulates IGF-I receptor activation and proliferation of human intestinal smooth muscle. fulvescens in particular, is the value placed on them by both the commercial caviar producing industry and by the recreational fisheries sector. Reporter genes for the study of transcriptional regulation in transgenic mouse embryos. The activity of GE was determined according to MeoSuc(Ala)2ProValpNa hydrolysis. Guided by the interpersonal-psychological theory of suicide, this cross-sectional study examined risk factors for suicide ideation and attempts among 312 men and 84 women arrested for domestic pamelor max dosage violence and mandated to attend batterer intervention programs. Using small-angle x-ray scattering and osmotic stress methods, we investigated the structure of SJW1660 flagellar filaments as well as the intermolecular forces that govern their assembly into dense hexagonal bundles. The validity of a professional competence tool for physiotherapy students in simulation-based clinical education: a Rasch analysis. This method could be one of the new suitable approaches to increase the resectability of liver tumours.

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