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Bupron (Bupropion)

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Bupron is used in the treatment of depression and smoking addiction. This medicine helps by increasing the level of chemical messengers in the brain that relax the nerves and have a calming effect on the brain.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Celexa, Aristocort, Maxalt, Valtrex, Dramamine, Floxin, Aldara, Parlodel, Cytoxan, Paxil

Also known as: Bupropion


Wellbutrin SR is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Wellbutrin SR with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Wellbutrin SR suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Wellbutrin SR (Wellbutrin or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Wellbutrin SR.

Store at room temperature away from moisture, heat, and light.

Detailed Wellbutrin SR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of bupropion can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Do not store it in the bathroom or near a sink. Do not leave it in the car or on window sills. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Bupron are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Wellbutrin XL if you are allergic to it, or if you have:

a seizure disorder; an eating disorder such as anorexia or bulimia; or if you have suddenly stopped using alcohol, seizure medication, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take Wellbutrin XL. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Wellbutrin XL to treat more than one condition at a time. If you take this medicine for depression, do not also take Wellbutrin XL to quit smoking.

Wellbutrin XL may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

Tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor; narrow-angle glaucoma; heart disease, high blood pressure, or a heart attack; diabetes; kidney or liver disease (especially cirrhosis); depression, bipolar disorder, or other mental illness; or if you drink alcohol.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Ask your doctor about taking this medicine if you are pregnant. It is not known whether Wellbutrin XL will harm an unborn baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Wellbutrin XL is not approved for use by anyone younger than 18 years old.

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All animals survived 14 days without complications, and cultures were negative. If rapid washing-out of permethrin could be overcome by novel technological approaches, insecticide-treated clothes might become a potentially cost-effective and scalable intervention to protect against diseases transmitted by Aedes mosquitoes such as dengue, Zika, and chikungunya. Dissection into subdomains that are able to confer tissue-specific gene expression has demonstrated that the promoter has a modular organization. Isolated systolic hypertension is an important clinical entity in the growing elderly population and can be appropriately diagnosed and managed by the nurse practitioner in primary care. The clinical utility of next-generation sequencing (NGS) in breast cancer has not been demonstrated. These drugs can be useful medical therapy, either used alone in selected patients or in combination with other therapeutic modalities. The present study introduces a new quantitative method that permits dose-effect analysis of these compounds.

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We have previously demonstrated that the onset of TCR alpha gene rearrangement is mainly restricted to the J alpha50 gene in fetal day 1delta thymocyte hybridomas. Fifty-two 3D structures of Ig-like domains covering the immunoglobulin fold family (IgFF) were compared and classified according to the conservation of their secondary structures. The effect of disease life history on the evolutionary emergence of novel pathogens. This is the first meta-analysis to assess the clinical efficiency, safety and potential advantages regarding the use of ABT drains compared with closed-suction/no drainage. In diabetic rats, the repeated exposure to physical stress markedly increased the DOI-induced wet-dog shake responses, but the repeated exposure to psychological stress had no effect. Because AMF can provide stress tolerance to their hosts, we suggest that extreme weather on the QTP may help drive a positive relationship between fertilizer amendment and AMF diversity. Antibody-mediated rejection (ABMR) has recently surfaced as a potential form of graft dysfunction after intestinal transplantation.

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In group III, the flap was elevated, the distal 4 X 3 cm was amputated and replaced as a full-thickness skin graft, and biopsies were obtained at 6 hours. Cerebrospinal fluid changes in experimental cardiac arrest (maximal stress). Here we analyze a large set of software class diagrams and show that several highly frequent network motifs appear to be a consequence of network heterogeneity and size, thus suggesting a somewhat less relevant role of functionality. The diffuse ghrelin immunostaining found in the parathyroid gland opens up the possibility of its secretion to the bloodstream or its involvement in the regulation of the parathyroid function. A technique was sought that would enable identification of surface-exposed parasite antigens on Babesia bovis-infected erythrocytes (BbIE) that are not detectable by surface-specific immunoprecipitations. Leishmaniases: new research findings and their implications in therapy and control. We therefore evaluated the effects of simvastatin treatment on the migratory capacity of brain microglial cells, key elements in the pathogenesis of MS. Partial compliance with assigned treatment regimes is common in drug trials and calls for a causal analysis of the effect of treatment actually received.

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While research has provided supportive evidence for both conceptualizations, recent research in cognitive psychology, especially the findings on mood and memory, might offer a broader framework to conceptualize depression as a multidimensional phenomenon. A Novel Sample Selection Strategy for Imbalanced Data of Biomedical Event Extraction with Joint Scoring Mechanism. PCR-RFLP analysis of the coagulase gene of Staphylococcus aureus: application to the differentiation of epidemic and sporadic methicillin-resistant strains. QUANTITATIVE CYTOCHEMISTRY OF THE CARCINOGENESIS IN THE RAT LIVER. We may speculate, that the sort of knowledge assessed with the written literature based true/false test is different from the sort of knowledge transferred during every day training: evidence based knowledge versus experience based knowledge. The mfERG (P1 mfERG responses central and peripheral) and retinal layer segmentation parameters (nine ETDRS subfields) were compared in vitiligo and control groups. Both of the brothers were born with mild hearing impairment, frontal bossing with prominent supraorbital ridges, downslanting palpebral fissures, dental malocclusion, and palatal clefts. In addition, the ACe contains numerous CRF-, NT-, SOM-, ENK- and SP-IR perikarya.

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In addition, future directions for the ECG are explored briefly. The multiple evolutionary origins of the eukaryotic N-glycosylation pathway. Sixteen original investigations were identified and analyzed for this review. In this study, the data were successfully reduced to three categories based on the 15th and 85th percentile allowing further analysis to proceed. A type-I interferon (IFN)-inducible protein, Mx, was identified in cultured glial cells after infection. Bronchogenic cysts of the mediastinum are benign anomalies of the ventral foregut. Effects of acupuncture at fengchi point (GB 20) on cerebral blood flow. Access to and utilization of primary care services among HIV-infected women.

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An experimental strategy validated to design cost-effective culture media based on response surface methodology. Effects of alpha-tocopherol and tocotrienols on blood pressure and linoleic acid metabolism in the spontaneously hypertensive rat (SHR). Because subjective health reports are a primary source of health information in a number of medical and research-based contexts, much research has been devoted to establishing the extent to which these self-reports of health correspond to health information from more objective sources. Days with appropriate wind direction but low peak ozone concentration are discussed in terms of coexisting weather parameters. The intracellular signal molecule cyclic di-GMP (c-di-GMP) is an important element in regulation of biofilm formation by bacteria. CD11/CD18 integrins have earlier been reported to interact with several cytoskeletal proteins. Acute renal failure after overdose of colloidal bismuth subcitrate.

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To this end, we implemented a matching-based modelling approach for optimal intervention group allocation, randomization and power calculations, which takes full account of the complex animal characteristics at baseline prior to interventions. The pineal contains a large number of classical transmitters and neuropeptides. Increased expression of NOX4 protein is associated with cancer progression and metastasis but the role of NOX4 in cell proliferation and invasion is not fully understood. Prognostic significance of p53 gene mutations and protein overexpression in localized gastrointestinal stromal tumours. Administration of human diploid-cell rabies vaccine in the gluteal area.

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After his mother accidentally revealed that he took complementary and alternative medicine, discontinuation of the therapy caused his condition to improve. The aim of the present work is to investigate the sedative-hypnotic effect of a rare dimeric napthoquione 1 obtained from the chloroform soluble fraction of D. STUDIES ON THE ROLE OF COMPLEMENT IN THE IMMUNE CLEARANCE OF ESCHERICHIA COLI AND RAT ERYTHROCYTES BY THE RETICULOENDOTHELIAL SYSTEM IN MICE. A TEST OF THE ROLE OF EPISTASIS IN DIVERGENCE UNDER UNIFORM SELECTION. This strategy involved mild reaction conditions with intent to restrict the thermal electrocyclic ring opening into (Z,E)-dienes. Feasibility on systemic delivery of asialoorosomucoid complex to hepatic origin cells mediated by asialoglycoprotein receptor. Other clinical applications for IGF assays in pediatrics are also reviewed. Dithiotreitol specifically inhibits metabotropic responses of glutamate and depolarizing agents in rat brain synaptoneurosomes. We also investigated whether a protocol adopted in 1994 of early subaortic resection at a preoperative mean systolic gradient across the left ventricular outflow tract (LV gradient) greater than 30 mm Hg was supported by longitudinal outcomes.

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Early HCV-associated stellate cell activation in aggressive recurrent HCV: what can liver allografts teach about HCV pathogenesis?. While research interest and public policy debate about paid maternity leave entitlements continues, little is known about the actual utilization of the 52 weeks unpaid parental leave that is currently available to all employees. Study results revealed persistency of AF and high preprocedure osteopontin level independently predicted AF recurrence in patients undergoing cryoballoon AF ablation. The compounds and internal standard are eluted from the extraction column with acetonitrile. The effect of yoga training on enhancement of Adrenocorticotropic hormone (ACTH) and cortisol levels in female patients with multiple sclerosis.

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Stranded Arrangement of Sporopollenin in the Exine of Microspores of Poa annua. T cells assume a fundamental function in immunosurveillance and maintenance of the cutaneous immune barrier, yet derangement of their requisite role effects a range of cutaneous autoimmune diseases with significant associated morbidity. We performed clinical, confocal scan, microbiologic and histopathologic examinations on two corneas from 2 young patients who underwent DALK for keratoconus. Natural killer activity of patients with chronic tonsillitis and chronic pneumonia. On the basis of the different slopes of the measurements under these two conditions the contractile force of the cells in isotonic conditions was calculated to be 0.96 x 10(5)Nm- dose of vasotec iv 2. Levosimendan, at concentrations below the therapeutic range in humans, protected myocytes from hydrogen peroxide-induced apoptosis.

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