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Bioquil (Ofloxacin)
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Bioquil

Bioquil is used to treat outer ear infections (swimmer's ear or ear canal infections) and middle ear infections. It works by stopping the growth of bacteria. This medication belongs to a class of drugs called quinolone antibiotics. This medication treats only bacterial ear infections.

Other names for this medication:
Albact, Bactocin, Bioquil, Biravid, Danoflox, Docofloxacine, Dolocep, Drovid, Ecuflox, Ermofan, Ethiflox, Evaflox, Ofloxacin

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Also known as: Ofloxacin

Description

Bioquil is an antibiotic useful for the treatment of a number of bacterial infections. When taken by mouth or injection into a vein this includes pneumonia, cellulitis, urinary tract infections, prostatitis, plague and certain types of infectious diarrhea. Other uses, along with other medications, include multidrug resistant tuberculosis. An eye drop may be used for a superficial bacterial infection of the eye and an ear drop may be used for otitis media when there is a hole in the ear drum.

When taken by mouth common side effects include vomiting, diarrhea, headache, and rash. Other serious side effect include tendon rupture, numbness due to nerve damage, seizures, and psychosis. Use in pregnancy is typically not recommended. Bioquil is in the fluoroquinolone family of medications. It works by interfering with the bacteria's DNA.

Dosage

Use Floxin otic exactly as directed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Shake the medicine well just before each use.

You may warm Floxin Otic ear drops before use by holding the bottle in your hand for 1 or 2 minutes. Using cold ear drops can cause dizziness.

To use the Floxin Otic ear drops:

Lie down or tilt your head with your ear facing upward. Open the ear canal by gently pulling your ear back, or pulling downward on the earlobe when giving Floxin Otic to a child. Hold the dropper upside down over your ear and drop the correct number of drops into the ear. Stay lying down or with your head tilted for at least 5 minutes. You may use a small piece of cotton to plug the ear and keep the medicine from draining out. If the patient being treated has ear tubes, the doctor may recommend gently pressing the tragus (part of the ear in front of the opening of the ear canal) four to five times in a pumping motion after administration of the drops. This may allow the drops to pass through the tubes into the middle ear. Follow the doctor's instructions.

Do not touch the dropper tip or place it directly in your ear. It may become contaminated. Wipe the tip with a clean tissue but do not wash with water or soap.

Use Floxin Otic for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics.

Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have new symptoms.

Store Floxin Otic at room temperature away from moisture, heat, and light. Throw away any unused medicine after your treatment is finished.

Detailed Floxin Otic dosage information

Overdose

Information on overdosage with Bioquil is limited. One incident of accidental overdosage has been reported. In this case, an adult female received 3 grams of Bioquil intravenously over 45 minutes. A blood sample obtained 15 minutes after the completion of the infusion revealed an Bioquil level of 39.3 µg/mL. In 7 h, the level had fallen to 16.2 µg/mL, and by 24 h to 2.7 µg/mL. During the infusion, the patient developed drowsiness, nausea, dizziness, hot and cold flushes, subjective facial swelling and numbness, slurring of speech, and mild to moderate disorientation. All complaints except the dizziness subsided within 1 h after discontinuation of the infusion. The dizziness, most bothersome while standing, resolved in approximately 9 h. Laboratory testing reportedly revealed no clinically significant changes in routine parameters in this patient.

In the event of an acute overdose, the stomach should be emptied. The patient should be observed and appropriate hydration maintained. Bioquil is not efficiently removed by hemodialysis or peritoneal dialysis.

Storage

Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bioquil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Floxin if you are allergic to ofloxacin or other fluoroquinolones (ciprofloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, and others).

Ofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This can happen during treatment or up to several months after you stop taking Floxin. Tendon problems may be more likely in certain people (children and older adults, or people who use steroid medicine or have had an organ transplant).

Tell your doctor if you have ever had:

tendon problems, bone problems, arthritis, or other joint problems; blood circulation problems, aneurysm, narrowing or hardening of the arteries; heart problems, high blood pressure; a genetic disease such as Marfan syndrome or Ehler's-Danlos syndrome; diabetes; a muscle or nerve disorder, such as myasthenia gravis; liver or kidney disease; a seizure; long QT syndrome (in you or a family member); or low levels of potassium in your blood (hypokalemia).

Floxin is not approved for use by anyone younger than 18 years old.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

You should not breast-feed while using this medicine.

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