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Atomoxetine

Atomoxetine is a medicine used in the treatment of attention deficit hyperactivity disorder (a behavioral disorder in children marked by poor concentration, hyperactivity, and learning difficulties). It helps to improve attention span, concentration and reduces impulsive behavior.

Other names for this medication:
Atomoxetine, Attentrol, Axepta, Tomoxetin

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Description

Atomoxetine is an FDA-approved medication taken for the treatment of attention deficit hyperactivity disorder (ADHD). Its active ingredient, Atomoxetine, is a selective norepinephrine reuptake inhibitor. Atomoxetine increases the balance of certain chemicals in the brain (e.g., norepinephrine), thereby decreasing impulsive behavior and hyperactivity. Atomoxetine may affect the attention span and behavior of the person taking it. It is also known as Atomoxetine, Attentrol, Tomoxetin, Attentin, Axepta.

Dosage

Usual Adult Dose for Attention Deficit Disorder:

-Initial Dose: 40 mg/day orally. -Maintenance Dose: Increase dose to 80 mg/day orally after a minimum of 3 days at the initial dose. -Maximum Dose: After 2 to 4 additional weeks, the dose may be increased up to 100 mg/day in patients who have not achieved an optimal response. Comments: Take dose once a day in the morning OR as evenly divided doses in the morning and late afternoon/early evening. Use: Treatment of Attention Deficit Hyperactivity Disorder (ADHD).

Usual Pediatric Dose for Attention Deficit Disorder:

70 kg or Less: -Initial Dose: 0.5 mg/kg/day orally. -Maintenance dose: Increase dose to 1.2 mg/kg/day after a minimum of 3 days at the initial dose. -Maximum dose: 1.4 mg/kg/day or 100 mg/day, whichever is less. Over 70 kg: -Initial Dose: 40 mg/day orally. -Maintenance dose: Increase dose to 80 mg/day after a minimum of 3 days at the initial dose. -Maximum dose: After 2 to 4 additional weeks, the dose may be increased up to 100 mg/day in patients who have not achieved an optimal response. Comments: Take dose once a day in the morning OR as evenly divided doses in the morning and late afternoon/early evening. Use: Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients age 6 and older.

Detailed Strattera dosage information

Overdose

If you overdose Generic Atomoxetine and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medication after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Atomoxetine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Atomoxetine if you are allergic to any of Atomoxetine’s components. Do not take Atomoxetine if you're pregnant or you plan to have a baby, or if you are a nursing mother. Do not take Atomoxetine if you are taking or have taken a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine) within the last 14 days. Do not take Atomoxetine if you have certain heart problems (e.g., heart defect, heart failure), certain types of irregular heartbeat, severe blood vessel problems, or narrow-angle glaucoma. Children and teenagers who take Atomoxetine may be at increased risk of suicidal thoughts or actions. Adults may also be affected. The risk may be greater in patients who have had suicidal thoughts or actions in the past. The risk may also be greater in patients who have had bipolar (manic-depression) illness, or if their family members have had it. Watch patients who take Atomoxetine closely. Do not open the capsules or take them apart. Wash your hands immediately after using Atomoxetine. Do not get Atomoxetine in your eye as it may cause irritation. If you get Atomoxetine in your eyes or nose, rinse at once with cool water. Lab tests, including heart rate, blood pressure, and liver function, may be performed while you use Atomoxetine. Use Atomoxetine with caution in the elderly. They may be more sensitive to its effects, especially dizziness. Corticosteroids may affect growth rate in children and teenagers in some cases. They may need regular growth checks while they take Atomoxetine. Atomoxetine should be used with extreme caution in children younger than 6 years old. Safety and effectiveness in these children has not been confirmed. Sit up or stand slowly, especially in the morning. Avoid consuming alcohol while taking Atomoxetine. Avoid driving or operating machinery, as atomoxetine can cause sleepiness or dizziness. Do not stop taking Atomoxetine suddenly.

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Hepatocyte IL-6 production was significantly increased following treatment with LPS, IL-1, and TNF. Electrical CV of persistent AF in an outpatient setting is feasible, safe and has a high patient-acceptance. Glutathione and metallothioneins as cellular defense against cadmium toxicity in cultured Chinese hamster cells. Enhancing effects of cytosine arabinoside on ethyl methanesulfonate-induced 6-thioguanine resistance mutations in Chinese hamster V79 cells. Further research on a large number of patients may be required before recommending clonidine in similar conditions. This paper describes a new type of sequential testing for clinical trials. We have developed a robust scoring system that can predict the risk of distant recurrence in node-positive cervical cancer patients after radical operation.

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