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Astrim (Trimethoprim)

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Astrim is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a sulfa drug.

Other names for this medication:
Avlotrin, Bacin, Bactiver, Bactoprim, Baktimol, Cadiprim, Ciplin, Cotrimol, Cotrimox, Cotrimstada, Danferane, Deprim, Dhatrin, Eusaprim, Groseptol, Kepinol, Kombitrim, Letus, Lupectrin, Medibiot, Megaset, Megatrim, Meprim, Methoxasol, Neoset, Nopil, Novidrine, Oribact, Regtin, Ribatrim, Septra, Suftrex, Sulphytrim, Sulprim, Sumetoprin, Trimesulfin, Trimethoprim, Trimexazol, Trimol, Trimosazol, Tripur, Trisul, Zoltrim

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Also known as: Trimethoprim


Astrim is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Astrim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Astrim DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


Adults: The usual adult dosage in the treatment of urinary tract infections is 1 Astrim DS (double strength) tablet or 2 Astrim tablets every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.

Children: The recommended dose for children with urinary tract infections or acute otitis media is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.


If you overdose Generic Astrim and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Astrim overdosage: dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of your skin or eyes, blood in urine, fever, confusion, fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Astrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Rapid translocation of NS and NPM to the nucleoplasm and suppression of new preribosomal RNA synthesis occurs in both neonatal rat cardiomyocytes (NRCM) and cardiac progenitor cells (CPC) upon exposure to doxorubicin or actinomycin D. Catabolism in vitro of 2-14C-thiazole-labeled thiamine by rat tissues. We show that the autoinflammation-associated H443P mutant is altered in interaction with SUG1 and ubiquitinated proteins, triggering constitutive caspase-8-mediated cell death dependent on FADD but independent of Ser533 phosphorylation. Thus, the APC/C is not only critical for anaphase onset but also regulates many other cellular processes during G1/S or in quiescent cells. We retrospectively reviewed 74 oncology patients admitted to the IPCU in August and September, 2013. Given access to suitable high end computing resources and a high degree of automation, we can compute individual binding affinities in a few hours with precisions no greater than 0.2 kcal/mol for TIES, and no larger than 0.34 and 1.71 kcal/mol for the 1- and 3-trajectory ESMACS approaches. Serum independent and dependent phagocytosis did not differ from healthy volunteers. The development of prospective memory in typically developing children. The structure of GRY oligomers formed during the early stage of amyloid fibril formation (1-4 days) has been examined by means of protein cross-linking with homobifunctional reagents.

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The enhanced P3a to novelty and subsequent positive wave instead of RON in alcoholics suggests encoding into working memory of task-irrelevant auditory events and provides neurophysiological markers of impaired involuntary attention mechanisms in chronic alcoholism. We describe, a case of scrotal and penile squamous cell carcinoma arising in a patient with a history of chronic scrotal and penile lymphedema of filarial origin. Quantitative cytochemical investigations on Ehrlich ascites tumour cells treated with vincristine. Functioning of the upper extremity after implantation of an endoprosthesis remains limited despite the achieved pain relief. However, it has recently been suggested that t-PA activity, in the cerebral parenchyma, may also potentiate excitotoxic neuronal death. It could be ruled out that the effect during the first 200 min was due to major infiltration of lymphocytes or neutrophils.

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Transitory spaces of care: serving homeless people on the street. We compared the performance of several family- and population-based imputation methods in large pedigrees provided by Genetic Analysis cleocin renal dosing Workshop 19 (GAW19). While the prevalence of particular arrhythmias with specific congenital heart disease has been previously described, a detailed analysis of all lesions and a large number of comorbidities has not been previously published. Effect of HMGCR variant alleles on low-density lipoprotein cholesterol-lowering response to atorvastatin in healthy Korean subjects. Relation of depression to perceived social support: results from a randomized adolescent depression prevention trial. Good glycemic, blood pressure, and lipid control have contributed to further reduce vision loss and laser photocoagulation.

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The root structure of Eleusine indica was not significantly affected by crude oil. Many of these genes, including preadipocyte factor-1 (Pref-1) and multiple members of the Wnt signalling pathway, are related to early adipogenic events. The emerging role of pituitary tumor transforming gene in tumorigenesis. FE analyses showed that geometrical design, thickness and abduction angle of the acetabular cup, as well as the clearance between the cup and head do change significantly the mechanical stresses experienced by biaxin antibiotic prophylaxis a cemented UHMWPE acetabular cup. Building on that, it was possible to combine all resource uses, as paid by the sickness funds, including those in ambulatory care. The risk decreased with increasing number of livebirths and with duration of oral contraceptive use. 35 deaths occurred associated with abortion, which was an increase, vs. If MSW were being managed today as it was in 1974, GHG emissions would be approximately 60 MMTCE. To assess the effect of two recalls of paracetamol products on rates of intentional and unintentional overdoses of paracetamol in all age groups, as well as any effect on poisoning by other agents. Convenient purification of human spleen fibrinolytic proteinase (SFP) and human leucocyte elastase by affinity chromatography.

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Markers of genes Lr1, Lr9, Lr10, Lr19, Lr20, Lr21, Lr24, and Lr26 have been used. To assess the association of single nucleotide polymorphisms (SNPs) of the low molecular weight polypeptide (LMP) gene with chronic hepatitis C virus (HCV) infection among ethnic Han population from Yunnan. Unconfounded randomised controlled trials in which anticoagulant therapy was compared with placebo or open control in patients with cerebral sinus thrombosis (confirmed by intra-arterial contrast or magnetic resonance angiography). We report a lady with a severe delayed reaction due to jellyfish envenomation that developed 2 days after contact with jellyfish tentacles. Bald olfactory vesicles, often containing basal bodies, are frequently observed. Our purpose was to evaluate the diagnostic performance of contrast maximum dosage of amaryl -enhanced and unenhanced MDCT, performed for various indications, in detecting choledocholithiasis. Self-regulation of exercise training intensity between grades 4 and 5 of the 10-point category-ratio BORG scale is effective but may promote overtraining in some patients without significant functional advantages.

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To resolve this problem, we suggest that the term EW be supplemented with terminology based on connectivity. Panniculitis is a rarely reported clinical finding in dermatomyositis. Somatic cell mutation frequency in vivo was measured in individuals with high cancer risk who were from ataxia telangiectasia (A-T) families. Only in stage III disease did elderly patients have worse CRS than young patients. Non-Dutch residents and Dutch residents born abroad, January 1, 1995. A low filtration fraction (less than 0.26) after implantation, measured 1 hour after implantation, correlated well with and predicted life sustaining kidney function. Forskolin and the phorbol ester 12-O-tetradecanoylphorbol 13-acetate stimulate prolactin and GH release from ovine anterior pituitary cells cultured in vitro. Growth hormone (GH) excess is an uncommon but potentially severe complication of MAS. A national survey of ED directors defined crowding, in part, as waiting more than 1 hour to see a physician, a wait considered likely to result in adverse outcomes. Exposure to hCG did not affect P production by luteal cells in early pregnancy.

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Trends in rates of different forms of diagnosed coronary heart disease, 1978 to 2000: prospective, population based study of British men. RFLP with HaeIII, MspI norvasc 5 mg tablets , HinfI, HhaI, HpaII, EcoRI, HindIII, PstI, RsaI, Taq alphaI, and AluI enzymes over ITS domains and 5.8 rDNA genes of C. Could the prevention of arterial essential hypertension rely on a objective view of the risk?. A series of functional, biochemical, and clinical studies established NEDD9 as a bona fide melanoma metastasis gene. To report the additional clinical value of real-time Polymerase chain reaction (PCR) in the detection of Treponema pallidum in aqueous humor. At interview with the patient it is important to emphasize that reconstruction of the tubes is a major operation and carries an increased subsequent hazard of ectopic pregnancy. Factors affecting the design of control systems for prosthetic devices.

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