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Aspitrate (Isosorbide)

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Aspitrate is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. Aspitrate is a nitrate vasodilator, which means that it works to relax your blood vessels. This makes it easier for your heart to pump, relieving heart-related chest pain.

Other names for this medication:
Aspitrate, Dilatrate, Ecosmin, Ismorin, Ismotic, Isoditrate, Isoloprin, Isordil, Isosorbide, Monit, Monoket, Monosprin, Nitren, Nitrofix, Nitroprin, Solosprin, Vasoprin

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Prandin, Deltasone, Hytrin, Mysoline, Remeron, Cytoxan, Avapro

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Also known as: Isosorbide


Imdur (isosorbide mononitrate) is a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.

Imdur is an extended release tablet used to prevent angina attacks (chest pain).

Imdur will not treat an angina attack that has already begun.


This section provides information on the proper use of a number of products that contain isosorbide mononitrate. It may not be specific to Imdur ER. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This form of nitrate is used to reduce the number of angina attacks over a long time. It will not relieve an attack that has already started because it works too slowly. The extended-release form gradually releases medicine to provide its effect for 8 to 10 hours. Check with your doctor if you also need a fast-acting medicine to relieve the pain of an angina attack.

You should take this medicine first thing in the morning and follow the same schedule each day. This medicine works best if you have a "drug-free" period of time every day when you do not take it. Your doctor will schedule your doses during the day to allow for a drug-free time. Follow the schedule of dosing carefully so the medicine will work properly.

Swallow the extended-release tablet whole with a half glass of water. Do not split, crush, or chew it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For prevention of angina: For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Take the dose in the morning right after you wake up. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—20 milligrams (mg) two times a day. Take the first dose in the morning right after you wake up, and the second dose 7 hours later. Children—Use and dose must be determined by your doctor.


If you overdose Generic Aspitrate and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Aspitrate are difficult or slow breathing, muscle cramps, nausea, vomiting, diarrhea, high temperature, fainting, abnormal heartbeat, changes in vision, flushing, convulsions, severe throbbing migraine, lightheadedness.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aspitrate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Imdur if:

you are allergic to isosorbide mononitrate, isosorbide dinitrate, or nitroglycerin; or you have early signs of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating).

You should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking Imdur. Taking these medicines together can cause a sudden and serious decrease in blood pressure.

To make sure Imdur is safe for you, tell your doctor if you have:

congestive heart failure; kidney disease; or low blood pressure.

It is not known whether Imdur will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether isosorbide mononitrate passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

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Polymerase-Mediated Site-Specific Incorporation of a Synthetic Fluorescent Isomorphic G Surrogate into RNA. These relations suggest that parathyroid hormone rather than a rise in the extracellular calcium concentration is associated with a spectrum of left ventricular hypertrophy. The right inferior frontal gyrus (rIFG) has been hypothesized to mediate response inhibition. Brief bursts of parallel fiber activity trigger calcium signals in bergmann glia. Their self-perceptions of coping ability, self-esteem, and interpersonal relations were also lower. Genomic DNA was isolated from 129 infants who were either growth retarded or appropriately grown for gestational age xanax dose before root canal . Five themes emerged from the analysis of the data, which described the coping strategies of the children: (1) problem-solving, (2) acting-out, (3) avoidance, (4) seeking help and (5) self-regulation. We describe ethnographic research conducted in a special needs school in SA to explore the lived experiences of children with cerebral palsy and their involvement in physical activity. This paper presents a practical instructional model for percutaneous umbilical cord sampling.

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