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Aristrol (Calcitriol)

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Aristrol is a hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give Aristrol.

Other names for this medication:
Alfabond, Alfacalcirol, Apcical, Arachitol, Arcium, Aristrol, Bonetuf, Calbec, Calcibest, Calcimet, Calgel, Calosto, Calotec, Calsonic, Calzem, Estovon, Fovit, Lctrol, Novadee, Osteobel, Qpcal, Rical, Riecal, Ritoca, Rolsical, Romical, Sorvate

Similar Products:
Seroquel, Coreg, Prevacid, Revia, Sustiva, Ambien, Neurontin, Singulair, Medrol, Benemid

Also known as: Calcitriol


Generic Aristrol is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Aristrol are intestine and bone. Generic Aristrol receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Aristrol may also act on the kidney and the parathyroid glands. Generic Aristrol is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Aristrol has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Aristrol, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Aristrol in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Aristrol produces other independent beneficial effects. Aristrol is also known as Calcitriol. Generic Aristrol treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Aristrol is Calcitriol. Brand name of Generic Aristrol is Aristrol.


This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Rocaltrol. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.


If you overdose Generic Aristrol and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aristrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Problems in older adults have not been reported with intake of normal daily recommended amounts. Studies have shown that older adults may have lower blood levels of vitamin D than younger adults, especially those who have little exposure to sunlight. Your health care professional may recommend that you take a vitamin supplement that contains vitamin D.

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The Association between Warning Label Requirements and Cigarette Smoking Prevalence by Education-Findings from the Global Adult Tobacco Survey (GATS). Contributions of the Central Extended Amygdala to Fear and Anxiety. However, several methodological issues have not been resolved yet. The histological and histochemical changes were compared in the gastrocnemius muscles of 20 rats, in which the left sciatic nerve was frozen-crushed for 10 s at the level of the buttock. Studies by a combination of vascular perfusion, histological and electron microscopic techniques show that subcutaneous injection of air into rats excites no acute inflammatory response, but leads to the formation of a pouch lined by avascular fibrous tissue.

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The aim of this study was to clarify the relative advantages and disadvantages of surgical resection and colonoscopic snaring as means of treating large colorectal polyps. Positive schemas, psychopathology, and quality of life in children with pediatric cancer: A pilot study. The best hypothesis consisted of one Hydrogen Bond Acceptor (HBA), three Hydrophobic Aliphatic (HY-Al) and one Ring Aromatic (AR) features. The effects of sleep disturbances on cognitive performance under distraction in multiple sclerosis (MS) are not known. Five male patients with the persistent generalized lymphadenopathy syndrome also had a sicca complex. Inductive Powering of Subcutaneous Stimulators: Key Parameters and Their Impact on the Design Methodology. Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys. The results indicate potential for fulcrum-negating hand tools in reducing the time needed to acquire motor skills.

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Fragmented care for inner-city minority children with attention-deficit/hyperactivity disorder. A 63-year-old woman with atrial fibrillation presented clinical symptoms and signs of acute ischemia in the right lower extremity on the 17th postoperative day after revision total hip arthroplasty of the left hip for aseptic loosening of femoral component. During the period of cross-clamping, cardiac output gradually decreased in all groups. Membrane alterations linked to early interactions of HIV with the cell surface. The enzyme system mediating the deacetylation of cinobufagin (CB) at the 16-position to give deacetylCB was characterized in the rat. It is unclear at this time how the change in microglia shape and distribution is related to their neuroprotective / neurotoxic potential.

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Removal of elevated level of chromium in groundwater by the fabricated PANI/Fe3O4 nanocomposites. 1963.-The action of formaldehyde in concentrations sublethal for the culture appeared to be at least twofold. CHD mortality in the sedentary men was highly correlated with working capacity in all age groups. Results Serum chemerin concentrations were significantly higher in atrial fibrillation patients compared with healthy controls. The partially purified recombinant protein was used to raise rabbit polyclonal antisera and murine monoclonal antibodies. Developing a research agenda and promoting collaboration on Latino oral health issues are crucial.

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In vitro phagocytosis experiments showed that SRBC formed the rosette structure surrounding a Type I cell and both SRBC and latex beads (luminal diameter 0.79 micron) were swallowed by Type I cells in vivo. Among renal transplantations, the cost of CRT was higher than LRT (3.69 vs 3.55 million JPY). Thus, there is an urgent need to develop and evaluate the effect of treatment with IL-2 on immunological parameters zyprexa medication guide and outcome of patients with inoperable pancreatic carcinoma. Lipid metabolism and risk of myocardial infarction -- new findings and implications for treatment. Can Malaysian Young Adults Report Dietary Intake Using a Food Diary Mobile Application?.

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The refolding of GroES protein from 3 M Gdn-HCl was probed functionally by measuring the extent cost deltasone 5 mg of inhibition of GroEL ATPase activity and the enhancement of lactate dehydrogenase refolding yields in the presence of GroEL and ADP. However, systematic changes in availability of sites that are not monitored might induce trends in occupancy of monitored sites, a situation rarely considered by monitoring programs. Human alpha 2-HS-glycoprotein/bovine fetuin homologue in mice: identification and developmental regulation of the gene. This study did not support the separate scoring of a somatic sub-scale of the Malaise Inventory. Jaw metastasis is a very rare condition associated with lung cancer evolution. While epidemiological studies can suggest inheritance patterns, only by identification of specific genes, can inheritance patterns be proven.

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Phase I/II glucophage xr 500 mg tab trial of interferon-beta-serine in patients with renal cell carcinoma: immunological and biological effects. Heterotrophs are key contributors to nitrous oxide production in activated sludge under low C-to-N ratios during nitrification-Batch experiments and modeling. A linear significative relationship was evident between nuclear androgen receptor (ARn) levels and endogenous irEGF but not between nuclear estrogen receptors and irEGF: in ARn negative BPH samples, irEGF levels were lower than in ARn positive ones. At 10(-6) M, dexamethasone, prednisolone, or hydrocortisone alone had little effect on Daudi cell growth, but they greatly potentiated the antiproliferative activity of rIFN-alpha A. It is a single-molecule property and contains all mechanistic information of folding processes of biomolecules such as proteins and nucleic acids.

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Our findings do not support total reliance on pre-dialysis BIS alone for assessing volume status in HD patients, but rather BIS should be considered an aid to clinical assessment of volume status. Analyses of potentially confounding variables showed smoking to be strongly related to the presence of polyps. On the other hand, intensive treatment also resulted in statistically significant occurrence of adverse events (hypotension, syncope, renal injury of failure). We evaluated the yield and additionality of household contact and source case investigations in Swaziland, a TB/HIV high-burden setting, while prioritizing identification of childhood TB. In such P systems, at most one channel is established between neighboring regions, each channel associates norfloxacin and tinidazole tablets in marathi with one state in order to control communication at each step, and rules are used in a sequential manner: on each channel at most one rule can be used at each step. Three diabetes-management behaviors were also related to optimal glycemic control, which represent potentially modifiable factors for clinical interventions to improve D-HRQOL as well as glycemic control.

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