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Aripat (Aripiprazole)

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Aripiprazole is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in adults and teenagers 13 years of age and older.

Other names for this medication:
Apicord, Aridus, Arifril, Arilan, Arinex, Aripat, Aripicon, Aripiprazole, Aripra, Arpicin, Asprito, Biliff, Elrip, Pipra, Rizotal, Schizopra

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Also known as: Aripiprazole


Aripiprazole is used alone or together with other medicines to treat mental conditions such as bipolar I disorder (manic-depressive illness), major depressive disorder, and schizophrenia. It is also used in children to treat irritability associated with autistic disorder and Tourette syndrome. Aripiprazole works in the brain to change how certain chemicals affect patients. It is an antipsychotic agent.

This medicine is available only with your doctor's prescription. Abilify® oral solution was withdrawn from the market on May 15, 2015 and this dose form is not marketed by any generic manufacturers.


Abilify Maintena is injected into a muscle. A healthcare provider will give you this injection once every 4 to 8 weeks, depending on your condition. Your doctor may occasionally change your dosing schedule.

If you have never used Abilify Maintena before, your doctor may want to you also take this medicine by mouth (in tablet or liquid form) for a short time before your first injection. You may need to continue taking oral this medicine for up to 3 weeks after your first injection. Follow your doctor's dosing instructions very carefully.

Keep using all your anti-psychotic medications as directed by your doctor. Read the instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

Drink plenty of liquids. You can easily become dehydrated while using Abilify Maintena.

Your doctor will need to check your progress while you are using Abilify Maintena.

Detailed Abilify Maintena dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma.


Store Aripat at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aripat are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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In the case of topically applied substances, usually both lateral spreading and competitive penetration into the skin occur in parallel. This article provides information for community nurses on the background of PICC lines in the UK, and practical advice on how to clinically maintain and manage these lines. This indicates that benthic Baltic cyanobacteria contain potentially harmful cytotoxic compounds even though they do not produce microcystins or nodularins. Effects of Nao-Yi-An granule on activity of cytochrome c oxidase in hippocampus of experimental intracerebral hemorrhagic rats. When the immunoadsorbed fraction was examined by electron microscopy, coated vesicles and vesicle-free cages were found forming a quasicontinuous monolayer on the surface of the Staph A cells.

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Directional change in tunneling of subterranean termites (Isoptera: Rhinotermitidae) in response to decayed wood attractants. The requisite proteins and lipids are transported from their sites of synthesis to myelin via vesicles. Our results do not support the hypothesis that obesity is independently associated with a decline in kidney function. Glucuronidation is a major drug-metabolizing reaction in humans. There is evidence that there are new third-class X-tubes--electronic tubes with compensation for negative volumetric charge of electrons with positive gas ions. Street theater was used to convey another health message about the importance of water tap maintenance.

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We investigate in depth the case of organic materials, systems in which energy and charge transport stand to be improved by overcoming challenges that arise from the effects of static and dynamic disorder - structural and energetic - and from inherently strong electron-vibration couplings. Menstrual blood was taken for all the cases and controls and menstrual plasma was produced and stored under refrigeration and peroxidase activity was measures. Molar maximization theory did not accurately predict the results of either experiment. Using multi-channel functional near-infrared spectroscopy (fNIRS), we examined the activation of the anterior portion of the lateral prefrontal cortex (LPFC) of 12 healthy volunteers during the SE of tea samples. Site specific genome editing has been gradually employed in drug discovery and development process over the past few decades. Ejaculatory disorders: epidemiology and current approaches to definition, classification and subtyping. Usefulness is dependent on acquisition parameters and clinical indications for examination. Effect of vinblastine on distribution of murine leukemia virus-derived membrane-associated antigens.

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At the end of a week granulomas had passed through the wall to reach the alveolar spaces. Correlates of NP symptoms, including OA severity (Western Ontario and McMaster Universities Osteoarthritis Index, Von Korff Chronic Pain Grade pain subscale score), psychological factors (Centre for Epidemiological Studies Depression Scale, Pain Catastrophizing Scale), and concomitant medical conditions, were evaluated using logistic regression. We analyzed a total of 515 museum specimens and 146 voice recordings representing and encompassing the distributions of all named taxa, including those currently considered not valid. Progesterone withdrawal reduces paired-pulse inhibition in rat hippocampus: dependence on GABA(A) receptor alpha4 subunit upregulation. The genetic basis of antimicrobial resistance in Ontario isolates of Actinobacillus (Haemophilus) pleuropneumoniae was studied. Our objective was to determine whether a blog post highlighting the findings of a surgical research article would lead to increased dissemination of the article itself. The use of mass media including radio, television, and satellite has had some successes and failures in literacy programs.

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Comparison of adeno-associated viral vector serotypes for spinal cord and motor neuron gene delivery. A total of 121 cases were matched with patients with no evidence of systemic Candida infection during the hospitalization period under study (same ICU, date of ICU admission, age, sex, simplified acute physiology score (SAPS II), location of the patient before admission, type of admission). This cleavage greatly enhances the fusogenicity of the protein and is necessary for the formation of a fully functional Env protein complex. Mice were primed with an intraperitoneal injection of pregnant mare serum gonadotropin (PMSG) and were treated with an anti-rat MIF antibody and human chorionic gonadotropin (hCG) to induce ovulation. Functional pathway-defined MRI diffusion measures reveal increased transverse diffusivity of water in multiple sclerosis. Innovations such as randomized registry trials, which aim to facilitate design of low-cost randomized controlled trials built on existing infrastructure provided by large healthcare databases, are likely to make clinical research more efficient in coming years. To establish reference ranges for blood flow velocity waveforms (FVW) of the fetal aortic isthmus (AoI) during the second and third trimesters of pregnancy. Effect of exercise training on plasma cholesterol and cholesterol kinetics in adult female rats.

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Therefore, the primary pathology of CCh may not be within the conjunctiva itself. Radiographic examination showed multiple pulmonary nodules and an osteolytic cervical spine lesion. The disposition of the microvascularization of the urethra is superimposed on the orientation of the fibers of the muscular tunic. Conformational partitioning of the fusion peptide of HIV-1 gp41 and its structural analogs in bilayer membranes. The effect of hydrocortisone on erythrophagocytosis and on the induction of heme oxygenase. These same connections were subject to GABAA, GABAB, norepinephrine and serotonin modulation, revealing a multiplicity of modulatory autoreceptors and heteroreceptors on individual varicosities. A submaxillary gland cancer was found in 1 but no other malignant tumors occurred among them. The aim of this work was to study how CETP expression affects whole body cholesterol homeostasis.

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Preparing to lead change: An innovative curriculum integrating theory, group skills and authentic presence. Interestingly, however, replication of vvMDV1 was suppressed in the cells with L-meq or with both L-meq and meq, compared to untransfected cells. We suggest that the estrogen-inducible EBAG9 gene-product and the 22-1-1 defined antigen are structurally and functionally separate antigens. Variation in the individual subject of some parameters in blood coagulation and fibrinolysis. Although an avian homologue of the mammalian MC4-R has recently been identified, there is little information on the role of this receptor and the melanocortin system in avian feeding and body weight regulation. The dietary changes in Norway and especially in Oslo during the Second World War, with reduced fat intake and increased consumption of fish and fish products, was paralleled by a reduced incidence of and mortality from IHD. Stochastic population models for the analysis of the effects of demographic processes on social security systems. Biocompatible, surface functionalized mesoporous titania nanoparticles for intracellular imaging and anticancer drug delivery.

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Intuition usually results in poorer decisions than an evidence-based decision-making process. The analysis of the extractions, prepared under mild conditions using a fluorinated solvent (HFC 134-a), confirmed the natural occurrence of monomenthyl succinate in the leaves, ruling out the hypothesis that this constituent could be an artifact of the Soxhlet extraction process. External exposure metrics included personal air, hand rinse, and dermal patch samples collected from each applicator on 2 days in 2002-2003. It has been tested in an animal laboratory and has been used successfully in 27 human cases. Gait analysis was done on three terrains including normal level walking, upstairs and downstairs. The prevalence among men is lower that in neighboring countries but the incidence is similar. The adverse actions of some therapeutic drugs and chronic alcohol consumption is discussed in relationship to fetal alcohol syndrome and the accompanied mental and somatic abnormalities. We present a case of functionally significant diastolic coronary artery compression in a cardiac transplant recipient who was successfully treated with intracoronary stent placement.

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Following a brief review of the diagnostic issues related to the assessment of mediastinal adenopathies, the role of FDG-PET imaging in environment-induced lung diseases, including pneumoconiosis, smoking, and asthma are described. The immunosuppressive effects of polyethylene glycol-modified asparaginases from Vibrio succinogenes (PEG-asparaginase VS) and Escherichia coli (PEG-asparaginase EC) have been investigated in mice. To assess changes in insulin sensitivity in non-diabetic adults with schizophrenia or schizoaffective disorder treated with olanzapine or risperidone. Counterions at charged rodlike polymers exhibit a condensation transition at a critical temperature (or, equivalently, at a critical linear charge density for polymers), which dramatically influences various static and dynamic properties of charged polymer solutions. Singlet oxygen quenching by the water-soluble anthracyclines was observed and a second-order rate constant of approx. Mechanisms for nickel(0)/N-heterocyclic carbene-catalyzed intramolecular alkene hydroacylation: insights from a DFT study. Tolerance to ethanol and treatment of its abuse, some fundamental issues. Post-prandial plasma-free amino acids in adult coeliac disease after oral gluten and albumin. The between-line (genetic) variability could also be adjusted to quadratic polynomials, but the curvature parameters were not significant.

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The invasive forms are generally called zoites and the majority of them largely depend on a unique form of gliding motility to invade cells. Exploring the links between posttraumatic stress disorder and social support: processes and potential research avenues. Recommendations for the clinical practice of early discharge after delivery: conditions for proposing early homecoming (May 2004). A dislocation of both interphalangeal joints in a single finger is a rare injury. Using the freeze-fracture technique, the tight junctions of the human ciliary epithelium were studied from 8 to 24.5 weeks of gestation with regard to their ability to act as a barrier to tannic acid. The primary outcome measures were death or dependency at the end of long-term follow-up (at least 3 months) and adverse events.

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However, whereas all other TA families known to date poison macromolecules involved in translation or replication, the target of zeta toxins remained inscrutable. The author suggests that the only viable policy is to help couples realize their fertility objectives. In conclusion, the case presented emphasizes the importance of considering PAE as a possible cause of respiratory failure in patients with severe head injury. Parasitization of Manduca sexta larvae by the parasitoid wasp Cotesia congregata induces an impaired host immune response. Treatment with the low molecular weight heparin enoxaparin, approximately 1 mg/kg s.c., twice daily, based on early pregnancy weight. A genetic screen for multicopy suppressors of an ers1Delta yeast strain identified a novel gene, MEH1, which is implicated in regulating Ers1 function. In June 1999, the same nations who composed the ICPD came together to discuss the progress of the Program and formulated further goals. Metals bound to proteins perform a number of crucial biological reactions, including the oxidation of water by a manganese cluster in photosystem II.

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The dynamics of the ferromagnetic order parameter in thin magnetic films is strongly affected by the magnetomechanical coupling at certain resonance frequencies. The purpose of RTOG 97-12 was to determine the maximum tolerated dose (MTD) of thoracic radiation therapy (RT) with concurrent chemotherapy for patients with limited-stage small-cell lung cancer. Upstanding benefits: standing systems provide wheelchair users with numerous health benefits. During pregnancy, intracystic vascularized excrescences of an endometrial cyst indicate not only malignant transformation but also decidualization. The balloon is then inflated to minimum pressure with 10 ml of distilled water contained in a syringe. The aim of this study is to detect the expression of HDGF in 158 cases of surgically resected NSCLC and evaluate its clinical significance. The SGRHS required a database to record, track and report on student rural placements to satisfy Commonwealth reporting requirements, and for internal academic and administration staff use. FMLP/CB-activated neutrophils from cigarette smokers also inflicted increased oxidant-mediated damage to the DNA of cocultured mononuclear leucocytes, which was prevented by the inclusion of superoxide dismutase and catalase individually and in combination. It has been postulated that individuals with the Q368STOP mutation are derived from a common founder. Group A streptococci can cause a variety of diseases ranging from uncomplicated superficial infections to severe systemic infections associated with high morbidity and mortality.

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In the present study lacrimal fluid peroxidase activity of 8 healthy normocyclic women using low-dose oral contraceptives during the monthly cycle was determined. Neurodynamic tension was postulated to affect segmental muscle extensibility and stretch tolerance, and potentially also demonstrate extra-segmental and contralateral effects. This paper concludes that reproductive health and health care in African countries must be improved in view of the prevalence of high rates of maternal and perinatal mortality. Trefoil factor (TFF) peptides, with a 40-amino acid motif and including six conserved cysteine residues that form intramolecular disulfide bonds, are a family of mucin-associated secretory molecules mediating many physiological roles that maintain and restore gastrointestinal (GI) mucosal homeostasis. Improvements in surgical management have diminished complications and improved results. Diagnostic accuracy studies in nonimmune individuals with suspected malaria were included if they compared rapid tests with expert microscopic examination or polymerase chain reaction tests. Patient-reported outcomes for open versus laparoscopic living donor nephrectomy. Activation of phospholipase D by bradykinin and sphingosine 1-phosphate in A549 human lung adenocarcinoma cells via different GTP-binding proteins and protein kinase C delta signaling pathways. Selective serotonin reuptake inhibitors (SSRIs) are the first-line treatment for panic disorder.

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The outcome measure calculated for each was the number of pregnancies avoided, defined as the difference between the number expected to occur with no method and the number expected to occur using that method. Changes in VA diagnosis of schizophrenic and affective disorders after DSM-III. Effect of a CD4-depleting antibody on the development of Cryptococcus neoformans-induced allergic bronchopulmonary mycosis in mice. Such trials could have improved external validity were they incorporated into normal care. Association of Malignancy Prevalence With Test Properties and Performance of the Gene Expression Classifier in Indeterminate Thyroid Nodules. Complete and accurate reporting is necessary to enable readers to assess the potential for bias in the study and to evaluate the generalizability of the results. Yohimbine appeared to be a safe and effective antagonist for xylazine sedation in raptors. Nucleophilic attack by the bridging hydroxide is prochlorperazine compazine 5 mg tablet facilitated by abstraction of its proton by the side chain carboxylate of Asp285. All patients are alive with no recurrence of thrombosis at the time of this report. The accumulation of chronic inflammatory rheumatic diseases in a single workplace suggests that some environmental exposure in this damp office had triggered the diseases.

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In the rural farming societies, fertility was important in strengthening and developing the family wealth, status, and family structure. We performed a literature search of trials using MEDLINE (January 1966-December 2001), Dissertations Abstracts On-line, PSYCHINFO, BIOSIS, PubMed, and the Cochrane Controlled Trials Register. POLN has a processivity of DNA synthesis (1-100 nucleotides) similar to the exonuclease-deficient Klenow fragment of E. The Brn1 region was highly conserved among the species examined at the nucleotide and the amino acid levels. The quality improvement cycle provides a tool to assist rural practitioners wishing to work towards better quality health care. Radiological measures included plain radiography of the spine and magnetic resonance imaging.

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Using the Spinal Cord Toolbox, we sought to correlate measures of GM, WM, and cross-sectional area pathology on T2 MR imaging with motor disability in patients with acute flaccid myelitis. Histological description of tooth formation in adult Eretmodus cf. There is strong evidence that parasol RGCs are the provenance of the magnocellular (M) visual pathway and that midget RGCs give rise to the parvocellular (P) pathway. Comparison of the secondary structures of major variants in hop, tomato and persimmon after transfer to tomato suggested that maintenance of stem-loop structures in the left-hand half of the molecule is critical for infection. The data show an unexpected result: the growth rate of nucleated holes increases with increasing molecular weight, up to a limiting value beyond which the rate is approximately constant. Available experimental values for stearic acid show a spread of 68 kJ mol-1.

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Malignant neoplasmas of the paranasal sinuses are rare and present usually in advanced tumor stage due to the lack of early clinical symptoms. A meta-analytic review of HIV behavioral interventions for reducing sexual risk behavior of men who have sex with men. Functionality of androgen receptor-based gene expression imaging in hormone refractory prostate cancer. The treatment of muscle tics with dissimilar competing response practice. Left atrial volume elocon ointment dosage calculation by angiocardiography in children. jejuni strain 81116 and an aflagellate mutant (R2), and a whole-cell R2 sonicate, and by Western blotting.

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Antegrade pyelography gives excellent contrast images and can be used as first stage of a percutaneous nephrostomy. Peripheral inflammation and chronic constriction injury (CCI) of the sciatic nerve induced a significant increase in the percentage of phosphorylated (P-) p38-immunoreactive (IR) neurons, primarily small sized ones in bilateral DRGs. While in the RNAi group transfected with the small interfering dsRNA expression vector (pRNAT-U6.1/Neo-Snail) targeting Snail gene, E2 treatment did not have a significant effect on MMP-2 activity or E-cadherin protein in ES-2 and SKOV3 cells. Successful treatment of refractory peripheral T-cell lymphoma with a combination of fludarabine and cyclophosphamide. We also found two ds1 alleles for resistant phenotypes with a stop codon in the coding region. meningitidis serogroup C since 2001 led to a 10-fold decrease in the incidence of meningitis cases, vaccination against S. This study investigated EEG differences between children with attention-deficit/hyperactivity disorder (AD/HD) and matched control subjects, with either normal or low IQs. The two drugs were shown to be comparable in efficacy by both the subjective and objective parameters used to assess pain, stiffness, and movement. 3 ,7 ,19-Trihydroxy-5-androsten-17-one 3,19-diacetate: a potential precursor in the biosynthesis of B-ring unsaturated estrogens.

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We outline the features of the latest MR minipress medication half life imaging techniques for the diagnosis of ischemic heart disease, discuss their practical applications, and compare them with other imaging modalities. The pH value of buffer electrolyte, temperature, and the time of sample injection into the capillary were examined for their impact on the results of assay of L-proline. Leaf surface characteristics of apple seedlings, bean seedlings and kohlrabi plants and their impact on the retention and rainfastness of mancozeb. Time-effect relationship of chromosome aberrations in peripheral lymphocytes after radiation therapy for seminoma. The mixed-effects model was used to compare age-adjusted mean corneal ECD between donors with and without diabetes. Efforts to screen indoor environments for potential triggers and patient risk profiles for abnormal airway reactivity should routinely be undertaken. Our aim was to evaluate the predictive performance of these models in a Spanish population. Finally, when considering time-dependent feeding preferences, as observed in the field, we noted that the virus circulation could be amplified and that the timing of epidemic peaks could be changed.

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For this purpose we investigated the association of polymorphisms in the genes for angiotensin-converting enzyme (ACE) and angiotensinogen (AGT) with the development of PTDM. Studies on the mechanism of the synergistic carcinogenic response reported between ethylene and disulfiram and the implications for short term predictive screening tests. There was no association between mycoplasmal colonization and age, parity pregnancy, prior abortion, stillbirth, low birth weight infant, age at conception of first pregnancy, abnormal vaginal bleeding, vaginal discharge, pruritus, history of syphilis, pelvic inflamatory disease, and number of years of formal education. Trypsins constitute a subclass of the S1A family of serine peptidases found in all groups of animal and some bacteria. The immunohistochemical SP staining was used to determine the expressions of bcl-2 protein and p53 protein. These results suggest that pancreatic proteases may play a role in the control of brush-border disaccharidase activities during fetal development. The edited cytidines are often flanked by inverted repeats, but are largely distinct from those deaminated by APOBEC3A. On the determinants of infant mortality in underdeveloped countries.

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In endothelial tube formation assay, NGR-LDP-AE at low cytotoxic dose significantly inhibited the formation of intact tube networks. A simulation study with steel spheres was carried out to study the possible error of over-estimation of the postembolization volume due to the beam-hardening artifact. Coincidentally to this phenomenon, hypoxaemia, reduction in platelet and leucocyte counts, and an increase in number of platelet microaggregates could be observed. Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs. Recombinant protein A(SpA) produced in Escherichia coli or Bacillus subtilis bacteria did not induce activation of human peripheral mononuclear cells, whereas SpA preparations obtained singulair dosage by weight from naturally occurring Staphylococcus aureus bacteria as well as recombinant SpA from Staphylococcus xylosus were potent mitogens. The characterization of diseases and their course under conditions of the alimentary dystrophy which affected the Leningrad population is given. The present study demonstrates that functional auditory circuits are established in the chicken embryo at stages earlier than previously reported. Evaluation of nitrogen protecting groups in the synthesis of beta-amino acids.

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