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Aptogrel (Clopidogrel)

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Aptogrel is an antiplatelet medicine. It prevents platelets (a type of blood cell) from sticking together and forming a dangerous blood clot. Taking Aptogrel helps prevent blood clots if you have an increased risk of having them.

Other names for this medication:
Antiban, Anticog, Antiplar, Aplatin, Asicom, Caplor, Cenoza, Ceruvin, Clasprin, Clodrel, Cloflow, Clolyse, Clopidogrel, Clopigrel, Clopivas, Clopiwa, Cloplat, Cloprez, Clotsafe, Compivas, Dospin, Grelet, Myogrel, Oprin, Orawis, Pidgrel, Platloc, Plodrel, Starclop, Stromix, Synplatt, Thinrin, Thrombosprin, Torpido, Torplatt, Vivosprin

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Also known as: Clopidogrel


Plavix (clopidogrel) prevents platelets in your blood from sticking together to form an unwanted blood clot that could block an artery.

Plavix is used to lower your risk of having a stroke, blood clot, or serious heart problem after you've had a heart attack, severe chest pain (angina), or circulation problems.


Usual Adult Dose for Acute Coronary Syndrome:

Unstable Angina (UA)/Non-ST-Elevation Myocardial Infarction (NSTEMI): -Loading dose: 300 mg orally once -Maintenance dose: 75 mg orally once a day -Duration of therapy: Optimal duration unknown. ST-Elevation Myocardial Infarction (STEMI): -Loading dose: 300 mg orally once (OPTIONAL) -Maintenance dose: 75 mg orally once a day, with or without thrombolytics -Duration of therapy: Optimal duration unknown. Comments: -Administer this drug in combination with aspirin 75 mg to 325 mg orally once a day. -The benefit of this drug for patients who undergo primary percutaneous coronary intervention is unknown. Uses: Prevention of atherothrombotic events in patients with non-ST-segment elevation acute coronary syndrome (UA, NSTEMI, those who are to be managed medically, those who are to be managed with coronary revascularization) and STEMI.

Usual Adult Dose for Ischemic Stroke:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Usual Adult Dose for Myocardial Infarction:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Usual Adult Dose for Peripheral Arterial Disease:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Detailed Plavix dosage information


If you overdose Aptogrel and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Aptogrel overdosage: vomiting, abnormal bleeding or bruising, problems with breathing.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Aptogrel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Plavix if you are allergic to clopidogrel, or if you have:

any active bleeding; or a stomach ulcer or bleeding in the brain (such as from a head injury).

Tell your doctor if you have ever had:

an ulcer in your stomach or intestines; or a bleeding disorder or blood clotting disorder.

Plavix may not work as well if you have certain genetic factors that affect the breakdown of this medicine in your body. Your doctor may perform a blood test to make sure Plavix is right for you.

This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant.

You should not breastfeed while using this medicine.

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A comparative discussion of the advantages and disadvantages of the Supramid implant vs cartilage grafts and/or repositioning of alar cartilages is presented. In addition, evidence-based recommendations will be made for safely managing pain and disability associated with OA in patients with comorbidities, including cardiovascular disease, renal insufficiency, and risk factors for gastrointestinal bleeding. A homozygous T deletion in codon 105 was found resulting in a change of a highly conserved cysteine to valine followed by eight altered amino acids and a premature stop codon due to the frame-shift. Molecular and genetic abnormalities arising in these stem cells lead to a block in the normal programme of proliferation and differentiation and result in the development of the blood cancers known as the leukaemias and lymphomas. Fitting parameters for medical diagnostic x-ray transmission data. The neuroleptic compound haloperidol (0.1 mg/kg) was administered intraperitoneally 30 min before testing. Clinical characteristics, predictors of immune reconstitution inflammatory syndrome and long-term prognosis in patients with Kaposi sarcoma. H2O2-induced cell injury was blocked by simultaneous treatment by catalase, but not by superoxide dismutase.

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