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Apodruff (Ketoconazole)

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Apodruff (for the skin) is an antifungal medicine used to treat infections such as athlete's foot, jock itch, ringworm, and seborrhea (dry, flaking skin or dandruff). Apodruff is also used to treat a fungal infection called pityriasis, which causes scaly discolored patches on the skin of the neck, chest, arms, or legs.

Other names for this medication:
Apodruff, Arcolane, Clinhair, Danclear, Dancure, Dandcare, Danket, Danrof, Danruf, Danstop, Danzol, Emvate, Extina, Flakefree, Flakfree, Forfora, Funazole, Fungicide, Funginoc, Fungizole, Hairdruff, Hyphoral, Kekona, Keticon, Ketoco, Ketoconazole, Ketodan, Ketoriv, Ketosh, Ketosis, Ketotar, Ketovate, Ketozole, Kezop, Kuric, Nizral, Nodan, Novale, Ocona, Phytoral, Rivtar, Sarot, Sebotar, Seldruff, Silkin, Triben, Vdruf, Velkin, Xolegel

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Also known as: Ketoconazole


Ketoconazole is used to treat infections caused by a fungus or yeast. It works by killing the fungus or yeast or preventing its growth.

Ketoconazole cream is used to treat:

Athlete's foot (tinea pedis; ringworm of the foot); Ringworm of the body (tinea corporis); Ringworm of the groin (tinea cruris; jock itch); Seborrheic dermatitis; "Sun fungus" (tinea versicolor; pityriasis versicolor); and Yeast infection of the skin (cutaneous candidiasis).

Ketoconazole foam or gel is used to treat seborrheic dermatitis (scaly areas on your skin or scalp).

Ketoconazole 1% shampoo is used to treat dandruff.

Ketoconazole 2% shampoo is used to treat "sun fungus" (tinea versicolor; pityriasis versicolor).

This medicine may also be used for other fungus infections of the skin as determined by your doctor.

Most forms of this medicine are available only with your doctor's prescription. Some forms are available without a prescription. However, your doctor may have special instructions on the proper use for your medical condition.


You should take it by mouth with full glass of water. Take Apodruff once a day at the same time. If you want to achieve most effective results do not stop taking Apodruff suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Ask a doctor before using this medicine if you are pregnant.

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In vitro study of biosynthesis of protoporphyrin IX induced by delta-aminolevulinic acid in normal and cancerous cells of the human cervix. These findings in an animal model suggest that supplementation during pregnancy with methylation-related micronutrients can promote sex-specific myogenic maturation processes related to organismal growth and muscle metabolism. Subjects were selected to obtain comparisons of plasma MMP-3 levels between 60 progressors (21 taking doxycycline, 39 taking placebo) and 60 nonprogressors (30 taking doxycycline, 30 taking placebo) with respect to medial joint space narrowing (JSN) in the index knee. Picosecond time-resolved infrared study of 2-aminopurine ionisation in solution. A total of 140 out of 144 motile Plesiomonas shigelloides strains were typable with the aid of a set of 15 H-antisera designated by letter symbols a through o. Effects of the liposomes coated by chitosan and its derivatives on the gastrointestinal transit of insulin. Although there have been significant improvements, PTA continues to be associated with significant morbidity and mortality. Donald Morton led the surgical oncology department until his death.

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Actively screened patients were more frequently asymptomatic than passively detected cases, even when considering only patients with bacteriological confirmation. Finally, we characterized the activity of three typical cardiac ion channels of those cells, and demonstrated that hPSC-derived ventricular cardiomyocytes (hPSC-vCMs) were suitable for drug cardiac safety evaluation. To understand how these stromal and microenvironmental factors contribute to tumour physiology and how oxygen distributes within them, we have developed a lattice-based multiscalar cellular automaton model. Ammonia is not only a highly important gas for civilization but also contribute significantly for climate change and human health hazard. These sequences, termed the locus control region (LCR), include two erythroid specific and a number of less restricted DNaseI hypersensitive sites. Histologically, the protrusion was made up granulation tissue consisting of cell infiltration and renewed capillaries with or without regenerated epithelia.

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A rapid method for determining the sensitivity of Staphylococcus aureus to beta-lactams is described. SDS-polyacrylamide gel electrophoretic analysis of high molecular mass glycoproteins from human milk fat globules revealed that the pattern of bands is unique for each milk donor. It is suggested that the absence of freezing injury in the secondary hyphae was due to ultrastructural preservation of the plasma membrane, which resulted from avoidance of severe cellular deformation, while occurrence of freezing injury in the tertiary hyphae is considered to be due to ultrastructural changes in the plasma membrane caused by severe cellular deformation. Selective Cleavage of the HIV-1 TAR-RNA with a Peptide-Cyclen Conjugate. Many studies have demonstrated in animal experiments that persistent inflammation may accelerate the development of carcinoma. The purpose of this study was to determine whether coronary venous retroperfusion with pressure-controlled intermittent coronary sinus occlusion (PICSO) alone and in combination with coronary venous substrate enhancement using L-glutamate would decrease ischemic damage after surgical revascularization for an acute coronary occlusion.

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Inspired by a recent variational formulation for this problem on smooth surfaces, we present a corresponding model for triangle meshes. Learning curve in anatomo-electrophysiological correlations in subthalamic nucleus stimulation. The normal and pathologic appearance of the capsular-labral complex was assessed, and the labra were evaluated on the basis of morphology, signal intensity, presence of a tear, and attachment to the acetabulum. Review of Regulatory Emphasis on Transportation Safety in the United States, 2002-2009: Public versus Private Modes. Pressor responses persisted in paralyzed, ventilated animals and were thus not dependent upon concomitant respiratory changes. HIGH LEVELS OF GENETIC VARIABILITY IN THE HAPLOID MOSS PLAGIOMNIUM CILIARE.

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Using this methodology, we study information transduction in the WW domain of a key cell-cycle regulator Pin1. Microfibrils can exist as individual structures or associate with elastin to form elastic fibres. Short applications of L-glutamate to outside-out patches from hippocampal neurons in the presence and absence of MK-801 revealed that about 30 percent of L-glutamate-bound channels are open at the peak of the current. A number of recent studies have reported key roles for inflammation in the progression of diseased vessels and systematic heart failure. Using this novel system, the role of ras, c-myc, and multidrug-resistant gene (mdr1) expression in the metastatic and drug-resistant phenotype was examined. Basal expression of p21 plays a more important antiapoptosis role than stress-stimulated p21 in carcinoma cells. Furthermore, TNF-alpha neutralization decreased the potent apoptotic stimulus induced by zymosan. Anticancer effects of the novel 1alpha, 25-dihydroxyvitamin D3 hybrid analog QW1624F2-2 in human neuroblastoma. Significant differences in frequency of pre- and perinatal complications and in neuro-behavior between the BZD group and the reference group were found in all groups of items.

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Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer. The overexpression of cyclin E positively correlated with the decreasing degree of tumor differentiation, implicating a role for cyclin E in the promotion of tumorigenesis. One day after successful occlusion of the fistula, clinical symptoms disappeared. The American Malaria Program (1941-1946) and its sequelae for biomedical research after World War II. In addition, percentage of information transmitted for words at 55 dB SPL was significantly higher with TESM than with ACE for manner and voicing features for consonants in the initial word position. Bevacizumab-treated cells showed no signs of cellular damage compared with the control. A Scan-Line Forest Growing-Based Hand Segmentation Framework With Multipriority Vertex Stereo Matching for Wearable Devices. Activation of the apoptotic pathway also leads to increased accumulation of reactive oxygen species and autophagy. In many clinics, intraoperative sonography is used as a routine method in general surgery as well as in neurosurgery. We created a retrospective multicenter cohort of patients with (1) GCA diagnosed according to the American College of Rheumatology criteria between 1995 and 2015, and (2) stroke occurring at the time of GCA diagnosis or occurring within 4 weeks of starting GCA therapy.

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Control erythrocytes were incubated under aerobic conditions at 37 degrees C for the period of the experiment, i.e. 16 MS patients and 17 healthy controls (HCs) were enrolled and neuropsychologically assessed. Sequential clinical, haematological, biochemical, immunopathological and histopathological alterations in buffalo calves (Bubalus bubalis) intravenously infected with Absidia corymbifera. Phase change and the regulation of shoot morphogenesis in plants. The authors evaluated the clinical and pathologic findings in 19 patients with a vesical hemangioma. Unresolved infections are usually due to resistant bacteria and are treated by modification of therapy based on antimicrobial sensitivity testing. Antioxidant co depakote antipsychotic medication -enzyme Q, at a concentration of 10 micromol/l, partially prevented plasma membrane damage and mitochondrial dysfunction. Proteomic profiling of Gram-negative bacterial outer membrane vesicles: Current perspectives. Spousal loss through divorce or bereavement is associated with a large enduring increased AUD risk.

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Importantly, apelin-13 co-treatment also significantly attenuated cisplatin-induced cardiotoxicity in vivo by inhibiting myocardial cells apoptosis and improving angiogenesis in mice heart. Determination of radiolabel efflux from 3H-DA-loaded vesicles indicated that in vitro ACR did not affect neurotransmitter retention. An update on the mechanism of action of the Steroidogenic Acute Regulatory (StAR) protein. Intracranial germ cell tumour in association with cryptorchidism. A 20-min pre- and postintervention heart rate variability (HRV) stress test and daily perceived stress via diaries assessed intervention efficacy. Addition of exogenous growth hormone did not appear to influence the expression of CDMP-1 or CDMP-2. The glucocorticoid-mediated TAT expression was inhibited by cycloheximide, a protein synthesis inhibitor, and by RU486, a glucocorticoid antagonist, suggesting that protonix medication classification glucocorticoid induction requires protein synthesis and may be mediated through hormone receptors. These injuries are impacting all professionals providing services in the health care arena including nurses, physicians, and household cleaning employees. The authors investigated whether MMP-2 and MMP-9 alter the expression of VEGF by retinal pigment epithelial (RPE) cells.

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In situ observations of RRT activations were performed pre- and post-training intervention. In this pathway, 1-deoxy-D-xylulose 5-phosphate (DOXP), the first intermediate, is transformed to 2-C-methyl-D-erythritol 4-phosphate (MEP) by an enzyme which was recently cloned from Escherichia coli. Recent reports of spatial working memory deficits in schizophrenia provide evidence for dorsolateral prefrontal cortical (DLPFC) dysfunction. Evidence for the influence of genetic factors has come from twin and family aggregation studies. Although not previously associated with vascular smooth muscle cells, REST is present and recruited to the KCNN4 gene in situ. Biochemical analysis and histopathological classification were carried out in the same samples. We evaluated the degree of atherosclerosis and endothelial function of ankylosing spondylitis patients ultrasonographically.

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To determine whether adult bone marrow-derived cells containing normal cystic fibrosis transmembrane conductance regulator protein (CFTR) could repopulate lung epithelium in transgenic mice deficient in that protein. We report here that overexpression of HEF1 causes an increase in centrosome numbers and multipolar spindles, resembling defects induced by manipulation of the mitotic regulatory kinase Aurora-A (AurA). The impact of phi testing in the real-world clinical setting has not been previously assessed. In preclinical models of breast cancer that faithfully recapitulate the disparate clinical responses in these microenvironments, we observed that brain metastases evade phosphatidylinositide 3-kinase (PI3K) inhibition despite drug accumulation in the brain lesions. To determine perceived barriers and facilitators to KTx that dialysis patients in this region experience, we conducted three focus groups with 40 total patients in Georgia, North Carolina, and South Carolina. In DT40 cells, treatment with trichostatin A increased both the amounts of IgM H-chain mRNAs and the switch from mu(m) to mu(s) mRNAs.

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