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Aplenzin (Bupropion)

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Aplenzin helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better, and increases your energy levels.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Lipitor, Viagra, Arcoxia, Zanaflex, Calan

Also known as: Bupropion


Wellbutrin (bupropion) is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Wellbutrin SR with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Wellbutrin SR suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Wellbutrin SR (Wellbutrin or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Wellbutrin SR.

Store at room temperature away from moisture, heat, and light.

Detailed Wellbutrin SR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Wellbutrin XL can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Do not freeze. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aplenzin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Wellbutrin XL if you are allergic to it, or if you have:

a seizure disorder; an eating disorder such as anorexia or bulimia; or if you have suddenly stopped using alcohol, seizure medication, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take Wellbutrin XL. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Wellbutrin XL to treat more than one condition at a time. If you take this medicine for depression, do not also take Wellbutrin XL to quit smoking.

Wellbutrin XL may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

Tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor; narrow-angle glaucoma; heart disease, high blood pressure, or a heart attack; diabetes; kidney or liver disease (especially cirrhosis); depression, bipolar disorder, or other mental illness; or if you drink alcohol.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Ask your doctor about taking this medicine if you are pregnant. It is not known whether Wellbutrin XL will harm an unborn baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Wellbutrin XL is not approved for use by anyone younger than 18 years old.

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Equilibrium and local stability in a logistic matrix model for age-structured populations. The Updated Nursing Professional Development Scope and Standards of Practice. The onset of clinical symptoms was very early, with severe neurological involvement, seizures that were difficult to treat and profound psychomotor retardation. Genetic diversity in the yeast species Malassezia pachydermatis analysed by multilocus enzyme electrophoresis. Foetal distribution of inhaled mercury vapor in normal and acatalasaemic mice. Impact of AIDS on adult mortality: a morgue-based study in Pointe-Noire, Republic of Congo. Selecting the best cell disruption method depends on the factors listed in Table 6.

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For individual species, there was a greater range of leaf size on south-facing slopes, while there was an absence of small-leaved species on north-facing slopes. In the case of human tissues obtained from autopsy or surgery, additional attention must be paid to the postmortem interval, temperature, hydration, and cause of death. The cervical spines of 15 male senescence-accelerated mice aged 8, 24, or 50 weeks were used for histologic and immunohistochemical examination of BMP-2/4 and BMP receptors IA, IB, and II. An adsorptive stripping voltammetric (AdSV) procedure for simultaneous determination of Ni(II) and Co(II) in the presence of nioxime as a complexing agent at an in situ plated lead film electrode was described. Top-down design of a picture archiving and communications system (PACS) by means of simulation. The levels of lutein and other carotenoids in the seeds were also significantly enhanced. A 16-year-old female with primary amenorrhea was diagnosed with TS based on karyotype 45,XO. Synthesis and biological activity of tuftsin and rigin derivatives containing monosaccharides or monosaccharide derivatives. The patient being described in this case report has the third isolated nonocclusive venous macroaneurysm to be reported. THE EFFECTS OF ACTINOMYCIN D AND MITOMYCIN C ON MOUSE TUMORS EXPLANTED TO THE CHORIOALLANTOIC MEMBRANE OF THE CHICK EMBRYO.

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Building upon previous work involving DNA-capped Fe3O4 nanoparticles for As(V) detection, we investigated two other nanomaterials: CeO2 and CePO4 in terms of DNA adsorption and As(V) induced DNA desorption. It may still be debated whether diabetic renal hypertrophy will inevitably lead to irreversible fibrotic changes in the absence of other factors such as altered intraglomerular hemodynamics and genetic predisposition. Particularly, the carboxyl ter-minal region containing 48 amino acids. As compared with completely edentulous patients, most of the patients required rehabilitation by a single implant. Yet, little evidence exists in undergraduate nursing programs on whether team communication skills affect team performance. Its activity affects the pharmacokinetics of commonly used drugs and limits the delivery of therapeutics into tumour cells, thus contributing to multidrug resistance. Localization of calcium in roots and microsomal membranes of corn by direct pyroantimonate precipitation.

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The pathological changes were presumably the result of the long-term clinical course of VWF. Quantified EEG and cortical evoked responses in patients with chronic traumatic frontal lesions. Aflatoxins containing B(1), B(2), G(1) and G(2) obtained by growing Aspergillus parasiticus on SMKY liquid medium were tested for cytotoxicity (hemolysis) on RBC suspension in the presence and absence of L-ascorbic acid (AA). Based on these experiments, a double extraction procedure was developed in which the receptor is solubilized subsequent to the solubilization of other membrane proteins. Self-relevant threat contexts enhance early processing of fear-conditioned faces. Taken together, our data indicates that the LHb exhibits intrinsic temporal oscillation in basal neurotransmission and in presynaptic release probability. Under the condition, NSPCs could differentiate into neurons, astrocytes, and oligodendrocytes.

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Conversion and maintenance of sinus rhythm by pharmacological or electrical methods become increasingly difficult the longer the arrhythmia persists. Biochemical progression-free, cancer-specific and overall survival curves were calculated by the Kaplan-Meier method. A Cox regression analysis was performed to determine which baseline variables predicted CV mortality. Recent studies indicate that administration of RA mitigates progressive kidney disease, underscoring its renoprotective potential. This study examines the role of BDNF in the spared nerve injury (SNI) mice model. According to the quality assurance system in a stem cell bank, each step of cell processing must be validated. The sympathomimetic effects of MIBG described here are not likely to come into play in patients given diagnostic or common therapeutic doses of radioiodinated MIBG. Electrocardiogram revealed intraventricular block, low voltage QRS complex, and ST-T abnormality. Its physiological role may be to protect the body from endogenous and exogenous cytotoxic agents.

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Analysis of data from the OECD Health Database, Better Life Index and the Israeli Central Bureau of Statistics, review of media reports and governmental documents concerning health measures, conversations and correspondence held with officials in the relevant organizations. Intravenous administration of mAb BV13 induced a concentration- and time-dependent increase in vascular permeability in heart and lungs. Collectively, the research reviewed briefly here highlight chemicals with the true potential to accelerate aging, particularly in the brain, by eliciting elevated free radical stress and mitochondrial dysfunction. Mean age at the time of surgery was 15 years 2 months (SD 4y 3mo). The altered tissue abundance of endoplasmic reticulum chaperones in thyroid cancer was correlated with serum expression levels.

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The content of endogenic ethanol (EE) and acetaldehyde (AcA) in blood, excretion of catecholamines (CA) with urine and their content in blood, functional activity of vegetative nerve system and central nerve system were studied in patients with chronic alcoholism in the period of short-term remission. Studies of intracellular recordings of CA3 pyramidal neurons showed that the amplitude of EPSP was dramatically enhanced by application of adenosine at low concentration (0.1 microM) without ultram tabs changing resting membrane potentials, membrane conductance or the threshold for spike generation by injecting current pulses. Cubosomes from hierarchical self-assembly of poly(ionic liquid) block copolymers. Thus, the 2-way chemotherapy of intravenous and intraperitoneal paclitaxel with S-1 was well-tolerated and was able to convert pancreatic cancer with peritoneal metastases to resectable disease. Post-fracture vascular phenomena and long-bone overgrowth in the immature skeleton of the rat.

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Based on information gathered within a program of studies (qualitative research exploring experiences, a cohort study examining service use), an expert advisory committee evaluated and integrated data, developed responses, formulated principles to inform care, and made recommendations for practice. For SIS, moderate evidence supported several passive modalities. Systematic Analysis of Palatal Rugae Pattern for Use in Human Identification between Two Different Populations. Clinicians may consider adjuvant strategies when these negative factors are present to increase the success of tailored ADHD treatments in the future. Total ligament growth was much less than that occurring at the tibial physis (which the ligament crosses). Radiation and tumor infiltration confer a high risk of bleeding on surgical removal of tumor. To determine the effects of cholinergic stimulation and inhibition on myoelectric, contractile, and emptying parameters of gastric motility. This occurrence strongly supports the alteration of glass to alkali-rich zeolite to analcime as the paragenetic sequence of alteration of tuffaceous rocks deposited in ancient Lake Gosiute. BCAR4 was higher in NSCLC tissues than that in cancer-adjacent tissues and was positively correlated with tumor size, clinical stage, and distant metastasis, suggesting that BCAR4 can be used as an independent predictor of prognosis. EFFECTS OF GUANETHIDINE AND RESERPINE ON EPINEPHRINE LIBERATION AND RENAL FUNCTION IN CATS.

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The role of ovarian sympathetic innervation in the control of estrous responsiveness in the rat. The self-assembled domain patterns of modulated systems are characteristic of a wide variety of chemical and physical systems, and are the result of competing interactions. Correction: Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes. We previously showed that ATF6 represents a novel transmembrane-type ERAD-L substrate requiring both EDEM1/2/3-mediated mannose trimming and SEL1L. The purpose of this quality improvement project was to improve identification of obese children and increase referrals to a weight management program. Conclusion remeron 30 mg picture for Practice The learning collaborative is a productive model to address the growing need for interdisciplinary MCH leaders. Letter re: The clinical spectrum of Caspr2 antibody-associated disease. It is hoped that these new criteria will serve to highlight an important and neglected form of dementia and provide the impetus for clinical and basic scientific research. Recent approaches of HCs regeneration provide new directions for finding the treatment of sensor neural deafness. cDNAs representing partial or full-length copies have been cloned in the plasmid pAT 153 and sequenced.

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Application of tetrazolium bromide to an in vitro chemosensitivity test. Thyroid function and morphology in patients affected by Williams syndrome. Characterization of a cDNA clone encoding a glycine-rich cuticular protein of Tenebrio molitor: developmental expression and effect of a juvenile hormone analogue. Exposure to the prevalent solvent used in dry cleaning (tetrachloroethylene) was evaluated by the trichloroacetic acid (TCA) concentration in the urine. HpyCH4 was found to be associated with certain renal parameters. Propagation of rhythms to transcriptional initiation involves the core promoter, its chromatin state, and the basal transcription machinery. The prefrontal cortex (PFC) is innervated by the monoamines, dopamine (DA), noradrenaline (NA), and serotonin, as well as acetylcholine, and the marked influence of these neurochemical systems on prefrontal working memory processes has been widely described. Thus, there appears to be a distinct phosphorylation site on the ABP molecule which is essential for regulating the initial proteolytic degradation of ABP by CDSP.

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A zinc oxide semi-conductor sensor was tested for ozone with calculation of the dependence of wanted signal on substance concentration. As a result, this could optimize orthopedic surgery outcomes, but, more importantly, patient health and satisfaction, while reducing costs of care. Prenatal and postnatal mothering by diesel exhaust PM2.5-exposed dams differentially program mouse energy metabolism. Patients treated more than 2 weeks after injury might benefit from ancillary fixation to limit subluxation (ie, cross pinning, external fixation, or internal joint stabilizer). Thermal variation and factors influencing vertical migration behavior in Daphnia populations. The following medications are contraindicated in breastfeeding: retinoids, methotrexate, mycophenolate, fumaric acid esters and ciclosporin. Sub-Saharan Africa is heavily dependent on global health initiatives (GHIs) for funding antiretroviral therapy (ART) scale-up. BROAD PROTECTIVE ACTION OF RABBIT ANTIPNEUMOCOCCUS SERUM IN RATS. Protection by a cyclic AMP-specific phosphodiesterase inhibitor, rolipram, and dibutyryl cyclic AMP against Propionibacterium acnes and lipopolysaccharide-induced mouse hepatitis. Intraoperative evaluation using mobile computed tomography in para que sirve la pastilla neurontin de 400 mg anterior cervical decompression with floating method for massive ossification of the posterior longitudinal ligament.

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