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Aplaket (Ticlopidine)
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Aplaket

Aplaket is a type of medication which is able to keep the platelets in your blood from clotting. This prevents the occurrence of any blood clots which can then contribute to certain heart or blood vessel conditions. The medication is normally prescribed to prevent blood clots occurring again after a recent heart attack or stroke, and also in people with certain disorders of the blood vessels or the heart within the human body.

Other names for this medication:
Aplaket, Astic, Taispin, Ticlantin, Ticlobest, Ticlogard, Ticlogaurd, Ticlop, Ticlopid, Ticlopidine, Ticlovas, Tikla, Tikleen, Tilkon, Tyklid

Similar Products:
Clarinex, Calan, Zyloprim, Sinequan, Hydrea, Ceftin

Also known as: Ticlopidine

Description

Ticlopidine is used to lessen the chance of having a stroke. It is given to people who have already had a stroke and to people with certain medical problems that may lead to a stroke. Because ticlopidine can cause serious side effects, especially during the first 3 months of treatment, it is used mostly for people who cannot take aspirin to prevent strokes.

A stroke may occur when blood flow to the brain is interrupted by a blood clot. Ticlopidine reduces the chance that a harmful blood clot will form, by preventing certain cells in the blood from clumping together. This effect of ticlopidine may also increase the chance of serious bleeding in some people.

This medicine is available only with a doctor's prescription.

Dosage

Ticlopidine should be taken with food. This increases the amount of medicine that is absorbed into the body. It may also lessen the chance of stomach upset.

Take this medicine only as directed by your doctor. Ticlopidine will not work properly if you take less of it than directed. Taking more ticlopidine than directed may increase the chance of serious side effects without increasing the helpful effects.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For prevention of strokes: Adults—1 tablet (250 mg) two times a day, with food. Children—It is not likely that ticlopidine would be used to help prevent strokes in children. If a child needs this medicine, however, the dose would have to be determined by the doctor. For prevention of strokes or heart attack following heart stent procedure: Adults—1 tablet (250 mg) two times a day, with food together with your doctor's recommended dose of aspirin for up to 30 days following the procedure Children—It is not likely that ticlopidine would be used to help prevent strokes or heart attack in children. If a child needs this medicine, however, the dose would have to be determined by the doctor

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Ticlid dosage information

Side effects

The most common side effects associated with Aplaket are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Effect of subarachnoid hemorrhage on endothelium-dependent vasodilation. We performed an international, interdisciplinary study on 51 individuals with SMC1A variants for physical and behavioral characteristics, and compare results to those in 67 individuals with NIPBL variants. PHYLOGENETIC RELATIONSHIPS OF NORTH AMERICAN URSIDS BASED ON ANALYSIS OF MITOCHONDRIAL DNA. Additional experiments performed in the presence of different concentrations of the GAD inhibitor valproic acid have shown the suitability of the proposed approach for the study of GAD inhibitors also. Interestingly, both PTEN-mutant U87MG and PTEN-wild-type LN-229 cells contain phosphorylated PKB constitutively. Although participants were not sure what to expect from the programme, they found it informative and for many this together with being in a group with other people with dystonia legitimised their condition. Mitochondrial protein import - Functional analysis of the highly diverged Tom22 orthologue of Trypanosoma brucei. 2 cases of severe cerebral complications during the course of chronic cor pulmonale syndrome.

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Genotypic and phenotypic data of 1,562 animals were analyzed to find genomic regions that potentially influence the birth weight (BW), weaning weight at seven months of age (WW) and yearling weight (YW) of Colombian Brahman cattle, with genotyping conducted using Illumina Bead chip array with 74,669 SNPs. Is 8-mm more effective than 4-mm tip electrode catheter for ablation of typical atrial flutter?. Introduction and expression of foreign genes into plant cells using a Ti plasmid vector. Cross-cultural Adaptation of the Oral Anticoagulation Knowledge Test to the Brazilian Portuguese. Following a clinical suspect of CS based on specific features, molecular screening of HRAS gene mutations should precede analysis of the other genes in the Ras-MAPK pathway implicated in related disorders with overlapping phenotypes.

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THE BASIS OF INDIVIDUALITY IN ORGANISMS FROM THE STANDPOINT OF CYTOLOGY AND EMBRYOLOGY. After neoadjuvant therapy for gastroesophageal adenocarcinoma, survival is determined by the same factors as after surgery alone. The accuracy of the method is investigated using model-generated data with parameters close to the parameters inferred in the experiment. Breast cancer treatment and natural history: new insights from results of screening. Harmonization of biotechnological regulations in the European Community.

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To analyse short-term changes in sick-leave use after the implementation of sick-pay cut policy in Estonia on July 1, 2009. To examine predictors of intentional and unintentional nonadherence to antihypertensive medication regimens and their relationships to blood pressure outcomes. By detecting the resonance frequency shifts of the notch MPF, the transverse load can be determined. Minke whales are difficult to study and little information exists regarding their responses to anthropogenic sound. Endothelial lipase (EL) is a key determinant in plasma high-density lipoprotein-cholesterol. Morphological and Functional Differences between Athletes and Novices in Cortical Neuronal Networks. The comparative experiments demonstrate the superior performance of this novel method over existing state-of-the-art. Three regions were identified: one important in MHC class II binding, one in T cell recognition, and one in both functions.

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ticlid brand name 2020-03-13

Our results suggest that lipid metabolism and peroxidation are important for the development of inflammation, which is elevated in several complications associated with diabetes. Participants were psychiatry outpatients, limiting generalizability. In general, the findings of this comparative study are consistent with those performed in other countries on smaller samples. Spontaneous Minced Cartilage Procedure for Unexpectedly Large Femoral Condyle Surface Defect. These results allowed us to predict that 3-chlorotyramine possesses a significant affinity by the D2 -DR. However, the protein concentration in the pleural wash fluid did not increase, indicating that iC5b67 did not induce a capillary leak. In order to support both environmental and health policy there is a need for accurate estimates of the exposures that populations might experience. Results - In contrast to knee OA, TLR expression in CMC-I OA did not show grade-dependent overall profile changes, but PCA revealed that TLR expression profiles clustered according to their cellular compartment organization. As the appreciation for the importance of the environment in infectious disease transmission has grown, so too has interest in pathogen fate and transport. However, traditional subspace clustering methods can only be applied on data from one source, and how to extend these methods and enable the extensions to combine information from various data sources has become tenormin 25 mg a hot area of research.

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Unusual spin-polarized electron state in fullerene induced by carbon adatom defect. The daily number of hospitalizations in each city was extracted from the French hospital information system (PMSI) for cardiovascular diseases, cardiac diseases, ischemic heart diseases and stroke. THE INFLUENCE OF CARRIER SUBSTANCES ON THE QUANTITATIVE GAS CHROMATOGRAPHIC ANALYSIS OF HIGHER FATTY ACID METHYL ESTERS. Aerobic capacity, evaluated by cytochrome oxidase activity, was not modified by exercise, which, conversely, affected the rates of oxygen consumption of hyperthyroid preparations. We analysed patient experience data from the English Adult Inpatient Survey which is administered to 850 patients annually in each acute NHS Trusts in England. The sudden recruitment of gamma-tubulin to the centrosome at the onset of mitosis and its dynamic exchange throughout the cell cycle, do not require microtubules.

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The proposed approach provides practically useful utilities to prioritize SNPs, and fills the gap between SNP set analysis and biological functional studies. These findings indicate that leptin is one of the key regulators for inflammation and progression of fibrosis in various chronic liver diseases including NASH. Sequence of a 1.4 kb Eco RI fragment of Azotobacter vinelandii nif DNA. Transforming growth factor-beta1 and interleukin-1alpha also enhance RANKL gene expression in vitro but probably have no effect in vivo because they are maximally expressed early. Risk score points for predicting TR-ROP were derived from the regression coefficients of significant predictors in a multivariate logistic regression model. Prophylactic measures for this category of workers are recommended. Kinetic studies on drug-resistant variants of Escherichia coli thymidylate synthase: functional effects of amino acid substitutions at residue 4. The possibility of NMS occurring in people with mental handicap, who have a high cyclophosphamide adverse drug reactions level of neuroleptic drug prescription, must be borne in mind. Like c-fos, zif268 is markedly activated in striatum by cocaine and amphetamine. Genetic heterogeneity of Flavobacterium meningosepticum demonstrated by DNA-DNA hybridization.

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Insulin-producing beta-cells were found in some of the ducts of older Ins-EGF and Ins-EGFxKGF transgenic mice, and amylase-producing cells were observed within the islet structures of the double transgenic mice. Three groups of families from the collaborative Lipid Research Clinics Program Family Study were assessed: 1,146 selected at random, 483 obtained through hypercholesterolemic probands, and 177 selected from the random sample because a number had low HDL-C, the sample sizes being 4,279, 1,807 and 735, respectively. Identification and evaluation of simple cysts, complex cysts, and solid masses in these patients rely on imaging studies, including ultrasonography, computed tomography, and magnetic resonance imaging, each of which has advantages and disadvantages. itraconazole capsules 100mg uses in malayalam This would indicate that restriction to the development of EAE may reside outside of the immune system, perhaps involving antigen recognition or presentation in the CNS itself. A new metabolic muscle disease due to abnormal hexokinase activity. Posttraumatic gustatory neuralgia: a clinical model of trigeminal neuropathic pain. The HEROD database is freely accessible at http://bidd2.nus.edu.sg/herod/index.php. Changes in the ionic composition and shape of erythrocytes in response to cholera toxin.

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Acute, high dose-rate, exposure of the rat embryo on day 15 post-conception (PC) causes a reduction of brain weight in adult life that is proportional to the dose received. We analyze the computational complexity of codon context optimization and design exact and efficient heuristic gene recoding algorithms under reasonable constraint models. CO2 assimilation rates were consistently decreased in the NDH-suppressed plants under low and medium light intensities. In this perspective, earlier research mainly on host-guest chemistry and its evolution towards more extended structures by applying crystal engineering principles using second sphere coordination is described. The outlook and future goals for continuing education in gynecology.

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Solutions of two paramagnetic ions for use in nuclear magnetic resonance phantoms. The components of the Green-Lagrange strain tensor and the in-plane principal and maximum shear strains were evaluated from the DVC displacement field for the central and peripheral regions of the LC and the nasal, temporal, inferior, and superior quadrants surrounding the central retinal artery and vein. This study aimed to assess the impact of severe PPM on survival after aortic valve replacement (AVR). Limited data guide practice in evaluation and treatment of septic bursitis. The normality test of data was conducted using SPSS 17.0 Statistics. Therefore, radionuclide angiocardiography during rest and exercise provides useful assessment of patients before and after coronary artery bypass grafting. EXPERIENCES ON A SELF-CARE-WARD AT THE ORTHOPAEDIC HOSPITAL OF THE INVALID FOUNDATION.

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Finally, we propose a framework to integrate these molecular and physiological data into a composite score that measures biological aging in humans. We show that the binding of the ubiquitous TF, Oct-1, to lamin B1 was reversed under conditions of cellular stress caused, inter alia, by the chemical methylating agent methylmethanesulfonate (MMS). The model represents both microscopic and macroscopic features in granule structure, previously observed using in-situ molecular techniques, and can be effectively used to interpret these results. Rates of physician substance use were weighted to provide national prevalence estimates. To assess laryngeal motion in early glottic cancer in order to determine safe margins for partial larynx volumetric modulated arc therapy (PL-VMAT), and to quantify dosimetric advantages of PL-VMAT.

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