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Antirobe (Clindamycin)
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Antirobe

Antirobe (generic name: clindamycin; brand names include: Clindatec / Dalacin / Clinacin / Evoclin) is used to treat a wide variety of serious bacterial infections including infections of the respiratory tract, skin and soft tissue, pelvis, vagina, and abdomen. It is also used to treat bone and joint infections, particularly those caused by Staphylococcus aureus. Antirobe kills sensitive bacteria by stopping the production of essential proteins needed by the bacteria to survive.

Other names for this medication:
Aknet, Biodaclin, Borophen, Clendix, Clidacin, Clidan, Clinacnyl, Clinbercin, Clindabeta, Clindacutin, Clindahexal, Clindamicina, Clindamycine, Clindamyl, Clindasome, Clindastad, Clindoral, Daclin, Dalacin, Dalacine, Dermabel, Evoclin, Jutaclin, Klimicin, Klindamicin, Klindan, Lindasol, Luoqing, Meneklin, Milorin, Nufaclind, Tidact, Torgyn, Trexen

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Also known as: Clindamycin

Description

Clindamycin is used to treat bacterial infections. This medicine may be given to patients who have had an allergic reaction to penicillin. Clindamycin will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain clindamycin. It may not be specific to Cleocin Pediatric. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Take the capsule with a full glass (8 ounces) of water. This is to prevent irritation of the esophagus (tube between the throat and stomach).

Measure the oral liquid correctly using the marked measuring spoon that comes with the package. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you have a "strep'' infection, you should keep using this medicine for at least 10 days. This is especially important in "strep" infections. Serious heart problems could develop later if your infection is not cleared up completely. Also, if you stop taking this medicine too soon, your symptoms may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take each dose at evenly spaced times day and night. If you need help in planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules and solution): For treatment of bacterial infections: Adults—150 to 300 milligrams (mg) every 6 hours. For more severe infections, 300 to 450 mg every 6 hours. Children weighing 10 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 8 to 16 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 or 4 equal doses. For more severe infections, the dose is usually 16 to 25 mg per kg of body weight per day, divided into 3 or 4 equal doses. Children weighing 10 kg or less—Dose is based on body weight and must be determined by your doctor. The dose is usually 37.5 milligrams (mg) or 1/2 teaspoonful 3 times a day.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cleocin HCl dosage information

Side effects

The most common side effects associated with Antirobe are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Although appropriate studies on the relationship of age to the effects of clindamycin have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have colitis, which may require caution in patients receiving clindamycin.

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This is true even after correcting for confounding factors in a multivariate analysis. Thus, preliminary enthusiasm over the efficacy of these new reagents must be tempered with the knowledge that their use in the clinic may be limited by the host immune responses or other as yet undefined factors. It is shown that freeze-thaw cycles cause significant NAPL remobilization in the direction of the freezing front, due to the rupture and transport of a significant proportion of (supposedly entrapped) larger multipore NAPL ganglia. Antibody reactivity to surface antigens which were significantly correlated with resistance and present in two or more of the preparations were detected at 86, 66, 51, 49, 34, 31, and 16 kilodaltons (kDa). Fewer cases of acute poisoning appear to take place than might be expected. Genetic susceptibility or prenatal acquired vulnerabilities regarding stroke syndromes may set in motion a cascade of molecular pathways that ultimately cause or exacerbate brain injury when the vulnerable child experiences adverse medical conditions. The assessment of other grip forms, such as pincer grasp, precision grip, pinch grip, and especially palmar abduction, leads to a relevant improvement in the diagnostics of distal median nerve lesion. Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. In this study we compared the time course of RTW after stroke in Japan that was reported in two cohort studies performed 20 years apart. Enhanced liver regeneration in IL-10-deficient mice after partial hepatectomy via stimulating inflammatory response and activating hepatocyte STAT3.

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All six size variants observed in this study show almost the same basic primary structure in which three repeat regions (A, B, and C) are interspersed by highly conserved nonrepeating sections. A clinical study of 650 vitiligo cases and their classification. Little information is available on delayed hypersensitivity reactions to spermatozoa, as well as histopathology and immunohistopathology of the testes and other organs in vasectomized individuals. Enhanced neuronal nitric oxide synthase expression is central to cardiac vagal phenotype in exercise-trained mice. Postoperative pancreatic fistula is the most common and potentially life-threatening complication after pancreatic surgery. Dynamics and configurational fluctuations of single DNA molecules in linear mixed flows. Because platelet activating factor (PAF) participates in the inflammatory process, the effect of a PAF-specific antagonist, BN52021, on the ovulatory response was tested in rats. Immunofluorescence staining supported the results of RT-PCR and flow cytometry. Beta-cyclodextrin significantly enhanced the cytotoxic activities of palladium (II) complexes and thiosemicarbazones probably by improving their solubility and bioavailability. Although extinction of the transgene after removal of tetracycline was rapid (less than 3 days), inducibility after addition of tetracycline was slow (about 14 days).

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The study was approved by the North West-Lancaster Research and Ethics committee (reference 15/NW/0801). The differential diagnosis concerning this rare tumor is also discussed. These observations suggest that Celiptium destabilizes the electrical properties of cell plasma membranes. The study demonstrates the feasibility of a successful pediatric liver transplant program in our country. Our hypotheses are that (1) mortality rates at high-quality pediatric cardiac programs are lower than published national results despite (2) a change in case mix with a shift away from low complexity operations. Here, we explored the association between testosterone levels and risk of death in male haemodialysis (HD) patients, whose arterial system is characterized by generalized stiffening.

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The steady state birth rate was found to be lower in the nondynastic model than in the Becker-Barro model. We have retrospectively analyzed the general health status and renal and cardiovascular consequences of living-related kidney donation. Subcutaneous and intramuscular atypical lipoma and well differentiated retroperitoneal liposarcoma. Identification of proteolytic cleavage sites in the conversion of profilaggrin to filaggrin in mammalian epidermis. These loops have a high density of basic residues, resulting in a positive charge on the surface of APC. Study of the preparations from reference strains of enterotoxigenic Escherichia. Finally, the Qrr mutation with in vivo defects also prevented Qrr/hapR binding, while the compensatory hapR mutation restored binding. One-hundred-and-fourteen patients received MRCP and unenhanced and contrast material-enhanced MR imaging. With the reporting of five studies with different and complementary designs, but all demonstrating a similar and striking benefit from the targeted drug trastuzumab in HER2-overexpressing breast cancer, the year 2005 has profoundly marked the history of randomised adjuvant breast cancer trials. Supplementary Notes on the Remote Control of Electrical Stimulation of the Nervous System.

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A complex of apically localized molecules mediates basal localization of cell fate determinants and apicobasal orientation of the mitotic spindle, but how daughter cell size is controlled remains unclear. Outcome of infants discharged from NICU on continuous treatment. Besides an overall decrease in mitochondrial gene expression, MDS patients displayed a stochiometric imbalance of mitochondrial-encoded genes, assessed in relation to the nuclear-encoded succinate dehydrogenase B. Combined genetic defects in a child with ischemic stroke: case report. Study 1: heads measured with plastic tape using both the WHO tight and UK loose technique. Significance of diagnostic procedures for renal transplant graft function. Serum transaminases, lipids, potassium, sodium, glucose and insulin were measured, and homeostatic model assessment-insulin resistance (HOMA-IR) and quantitative insulin sensitivity check index (QUICKI) were calculated before and 8( )weeks after baseline assessment. Overexpression of bradykinin type 2 receptors on glioma cells enhances bradykinin-mediated blood-brain tumor barrier permeability increase. Nonetheless the main antimutagenic fraction was not polyphenol, peptide nor nucleotide, its molecular weight being distributed about 5000-12,500.

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In contrast, in Caco-2 cells, Ro-26-9228 induces 40-fold less reporter gene expression than 1,25D(3) does. Patients with palpable regional lymph node metastases from melanoma (American Joint Committee on Cancer stage IIIB-C) underwent surgical biopsy at study entry and then received standard intravenous HDI (20 million units/m2, 5 days per week) for 4 weeks followed by complete lymphadenectomy and standard maintenance subcutaneous HDI (10 million units/m2 3 times per week) for 48 weeks. Morphological examination of these PSDs by electron microscopy revealed a preparation that seems to be quite pure, with little or no membrane contamination. In vivo, neutralization of PGE(2) from proangiogenic macrophage supernatants blocked vessel formation into Matrigel plugs. Human gut microbial degradation of flavonoids: structure-function relationships. Administrative medical records were obtained from the government of Quebec health insurance agency. Canadian adults with mood and/or anxiety disorders who reported lower levels of perceived stress and higher levels of social support and coping were more likely to report high levels of well-being. The wave reflection phenomenon at the open ends of the finite duct is described by general radiation impedance. On the basis of known and effective treatment strategies, IFN-induced depression should not be an obstacle for continued treatment in most patient populations. A comparison of salt-floatation and formol-ether techniques in demonstrating helminthic ova in faeces.

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Clinicians will find a discussion of possible clinical presentations and the risk of secondary transmission, in the context of progressing epidemics in countries, which have maintained close ties with France. Furthermore, in the parental cell lines, the administration sequence cisplatin followed by gemcitabine was synergistic, whereas the reversed schedule showed additivity and simultaneous administration revealed antagonistic cytotoxicity. We found that PHT, when administered without dietary supplementation, resulted in a decrease in weight and length of the fetuses, an increased rate of subcutaneous (s.c.) bleeding, a retardation of ossification centers, and an increased number of malformations. Differential effects of intrauterine and postnatal brain growth failure in infants of very low birth weight. Three of the seven hypothetical structures tested here can be rejected as having too many polar side-chain groups in the interior or too few on the protein surface. Patients were excluded from the study who were on aspirin before transplant or who had coronary artery disease. Glenohumeral cartilage lesions are found in up to one third of patients referred for MR arthrography for subacromial impingement syndrome.

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Highly enantioselective azadiene Diels-Alder reactions catalyzed by chiral N-heterocyclic carbenes. Molecular cloning and expression of a UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase that modifies Skp1 in the cytoplasm of dictyostelium. Two masked ophthalmologists independently graded the images for mottled, granular, and nummular patterns. An increase in the number of women who are heads of households is shown across most age groups and all types of union. Neither LT nor RM proved to be completely accurate in determining ridge width in the posterior mandible. third sector organisations offering volunteer support for pregnant women and new mothers can be valuable partners in reaching very disadvantaged women who may find it difficult to engage with services. Burnout is a problem that impacts on the staff management costs and on the patient care quality.

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In both bivariable (32/39 variables) and multivariable analyses (30/39 variables), note leavers differed from other suicides in most demographic variables, stressful life events, psychiatric issues, and methods of suicide. In immature mice, basal plasma glucose and insulin concentrations were higher than young adult mice. The methodology used is described, and assumptions concerning the age and sex structure of the base population and the levels and age patterns of mortality and fertility are discussed. Mitogen-activated protein kinase kinase 1 (MEK1) stabilizes MyoD through direct phosphorylation at tyrosine 156 during myogenic differentiation. They all presented with clinical signs of hemodynamic instability.

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Influence of cementing medium on the accuracy of the remount procedure. Faecal trypsin levels have been estimated by a photometric azo-casein method in 242 children and 45 adults. Relationship between risk factor control and vascular events in the SAMMPRIS trial. Stereoselective photooxidation of enecarbamates: reactivity of ozone vs singlet oxygen. Importantly, Adv/IL-10-transduced DCs were biologically active in vivo, in that administration of these DCs into mice before a generalized peritonitis significantly improved survival. A polyclonal antibody was raised against PAP III, and a Western blotting analysis using this antibody confirmed an increased level of PAP III protein in the injured nerve. In certain head tremors the eye movements observed may be normal vestibulo-ocular compensatory movements.

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An in vitro type 2 alveolar epithelial cell (L2) model and an ex vivo isolated reperfused rat lung model were used to determine the effects of BPA or MBP on cell growth and lung function. Suicidal ideation rates did not differ significantly between HS-OT group and controls. The direct involvement of mitochondrial activity in this cell behavior was studied by adding chloramphenicol, an inhibitor of mitochondrial protein synthesis, to the culture medium. Near what are the side effects of the drug actos infrared-sensitive video equipment was used to record swarming as it occurred in the field during each night of observation. We designed this study to determine the rate of settling and the amount of agitation needed to resuspend the preparation. The INK4a gene products, p16 and p14ARF, have been suggested as potential regulators of glioma chemo- and radiosensitivity. Hip fusion: a non-arthroplasty solution for the difficult patient. The first aim of this study was to investigate the effect of these compounds on human dermal fibroblasts in culture with or without TGF-beta1.

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The SSE program improved lower-extremity functional fitness, lack of which constitutes a risk factor for falls in the elderly. The recognition of early flat lesions presents a diagnostic challenge. To assess the frequency of class 1 integrons among isolates of Salmonella enterica producing different types of beta-lactamases from the health region of Tortosa, and to attempt to establish the resistance genes located within their variable regions. Comprehensive complications were defined as consensus criteria plus other adverse events: use of reversal agents, unplanned hospital admission, hospitalization beyond planned 23-hour observation, unplanned emergency department or primary care provider visit, and 30-day mortality. Recent delineation of vascular territories of the ear has allowed the use of vascularized helical free flaps in the repair of large alar defects. Their oncogenicity is usually ascribed to mitogenic or antiapoptotic action. Our model is an open system consisting of periodically distributed obstacles in the shape of a flower, and it is strongly chaotic for almost all parameter values. At least in rat piriform cortex, the suggestion that kainate receptors do not desensitize while those to glutamate and quisqualate do, does not apply to nor explain the more potent kainate excitotoxicity.

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Noradrenaline- and melatonin-mediated regulation of pigment aggregation in fish melanophores. Insertion of the human sodium iodide symporter to facilitate deep tissue imaging does not alter oncolytic or replication capability of a novel vaccinia klonopin medicine virus. In children with complicated appendicitis, LA should be carried out with caution and only by an experienced surgeon, as it is associated with a higher rate of conversion to open technique and more postoperative infectious complications. Compared with WKY neurons, SH neurons had higher firing rates in the preoptic-anterior hypothalamus and lower firing rates in the dorsomedial hypothalamus. It explicitly takes into account the interaction of the counterpropagating acoustic waves. Cancer prevention and early detection by appropriate screening methods in patients with diabetes should be important components of clinical management and investigation, inasmuch as the exponentially increasing prevalence of diabetes will translate into substantial clinical and public health consequences on a global scale. We find that in HeLa cells the cell cycle regulatory kinase, Wee-1, is depleted following prolonged G2 arrest induced by Vpr. In the EST all triazole compounds inhibited cardiomyocyte differentiation concentration-dependently.

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Dysfunction of mitochondrial respiratory chain complex I in human failing myocardium is not due to disturbed mitochondrial gene expression. Patients were evaluated according to a standard clinical protocol for ataxia patients. The presented results provide insight into the role of finger independency for different types of tasks and populations. Considerable progress has been made in our understanding of the molecular basis of Rh in the past 10 years. We show mathematically that a new GOF p-value, called the sampled posterior p-value (SPP), asymptotically has a uniform probability distribution whatever the discrepancy function. There were no significant difference in the cell proliferation and cell cycle distribution of NCI-H460 cells between concurrent treatment and the first sequential treatment. Radiologic criteria of MRI in diagnosing retropharyngeal lymph nodal metastasis of nasopharyngeal carcinoma. Titin organisation and the 3D architecture of the vertebrate-striated muscle I-band. Aromatase inhibitors might be more efficacious, and results of prevention trials are eagerly awaited.

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Thoracic three-dimensional spiral CT findings of an infant with spondylothoracic dysostosis. Systolic blood pressure incre-ments with running exercises at 10, 15, and 20 m/min were significantly greater in SHRSP than in WKY. Here, we discuss the most common tools for introducing and analyzing genetic mutations in M. Therefore, we investigated the effect of lactate on migration of endothelial cells. Added protection can be provided by coenzyme-A reductase inhibitors (statins), but probably not by antioxidants. A 57-year-old man presented with a liver mass that had been detected on physical examination.

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Laser Doppler flowmetry estimating myocardial plavix 600 mg winter springs fl perfusion after internal mammary artery grafting. Support is derived from the observed disinhibitory effects of a 10-second unpaired click/flash stimulus and of unsignaled, response-independent pellets that were presented while the animals were responding under the same schedule. Protection against rejection by impaired blood flow in a renal allograft. It also functions to limit vessel constriction and vessel wall remodeling. We performed a prospective observational study of pregnant women referred to our maternal-fetal medicine division with suspected HCMV infection. Tibiofibular torsion was in the clear lateral position from the beginning of the fetal period, with a positive gradient at birth.

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Primary reticulosarcoma of bone with an orbito-cranial localization. This data may prove useful in the separation of certain components of cellulase, since the non-foaming hydrophilic beta-glucosidase does not foam as well as the hydrophobic components of cellulase at low concentrations. Electron Beam Technology and Other Irradiation Technology Applications in the protonix dosing pediatrics Food Industry. We hypothesized that poor accuracy may be due to bulky tumor or complete replacement of lymph nodes by tumor. In this study, the collective comparative diversity of methanogenic archaea in the rumen of cattle and buffaloes was examined by performing a meta-analysis of all the 16S rRNA (rrn) sequences deposited in GenBank. The data are useful both for basic physiological understanding and for diagnosis and management of a variety of diseases and disorders. Advancing gene editing as a means of introducing targeted mutations into cccDNA thus potentially offers the means to cure infection by the virus. Liver function testing was performed for both groups in accordance with clinical guidelines. The growth mechanism of different morphologies based on the VS mechanism is emphasized.

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To gain insight into Bridge-1 function, immortalized, human breast cancer cells (MCF-7 cell line) were stimulated with activin A and the expression of Bridge-1 was analyzed by real-time PCR and Western blot. The combination of gemcitabine and cisplatin is active in patients who are platinum resistant. The autonomous parvovirus H-1 exhibits preferential toxicity for transformed or tumor cells. The search for an unknown primary tumour is often time-consuming, costly and unrewarding. Such structure is generally used jointly with other components in the construction of industrial high-power transducers.

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