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Amitriptyline works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood, relieve anxiety and tension, helps you sleep better, and increase your energy level. Amitriptyline is readily absorbed and starts action within approximately 6 hours of taking it orally.

Other names for this medication:
Abamax, Amiclozor, Amicure, Amidez, Amimax, Amitar, Amitone, Amitrac, Amitrim, Amitrip, Amitriptyline, Amitryn, Amiwel, Amixide, Amize, Amizep, Amoten, Amrea, Amtipax, Amtran, Amypres, Anitryp, Arpidox, Bluneel, Eliwel, Endep, Eptanol, Kamitrin, Latilin, Latiln, Libral, Limbitrol, Lodep, Mitrip, Mitryp, Nextrip, Normaline, Psycomer, Raitrip, Relidep, Ristryl, Sereval, Teedep, Typteez

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Amitriptyline target is the treatment of depression. Amitriptyline is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amitriptyline is Amitriptyline. Amitriptyline is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amitriptyline are Amitriptyline, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Elavil dosage information


If you overdose Amitriptyline and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitriptyline overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitriptyline are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amitriptyline if you are allergic to Amitriptyline components. Do not take Amitriptyline if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amitriptyline if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amitriptyline if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amitriptyline you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amitriptyline if you are going to have a surgery. It can be dangerous to stop Amitriptyline taking suddenly.

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The metabolic profile of cholesterol is maintained postprandially. Beta-CM mRNA and protein are expressed at low levels in the mammalian retina and RPE-choroid. The system comprises a continuous-wave phased-array transducer controlled by a purpose-built Doppler unit. Intramolecular dealkylation of chelating diamines with Ru(II) complexes. Surface protection using an appropriate ligand is essential for controlling the size, stability and luminescence properties of the quantum dots (QDs). Lipomatosis of the exocrine pancreas following D-penicillamine feeding of rats on choline deficiency diet. A Latent Class Analysis of Behavioral and Psychosocial Dimensions of Adolescent Sexuality: Exploring Race Differences.

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The molecular regulation of this neurogenic circuit is poorly understood. To study the relationship between islet hormonal secretion and intracellular content of five elements, a rat islet perifusion technique was used in 24 paired experiments. REACH 2010: working together to achieve the goal of eliminating health disparities. Variation of constitutive heterochromatin in the sex chromosomes of the rodent Bandicota bengalensis bengalensis (Gray). We aimed to measure the extent of unnecessary blood testing in a 33-bed intensive care unit (ICU) at a tertiary-care teaching hospital in Ontario, Canada. Effects of potentially functional polymorphisms in suppressor of cytokine signaling 3 (SOCS3) on the risk of head and neck squamous cancer. Furthermore, a meta-analysis of seven long-term studies has also shown that intervention with acarbose prevents myocardial infarction and cardiovascular diseases in type 2 diabetic patients. Male cholestatic patients, however, did not have significant increases in resorption parameters, although they were as osteopenic as female patients and had low bone formation markers.

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The influence of processing methods on the dissolution rate of phenacetin from tablets and granules. This article reviews current advances, major challenges, and future prospects in the field of urinary proteomics. Distribution of anomalous lysosomes in the beige mouse: a homologue of Chediak-Higashi syndrome. Based on the pilot test, item valence was made consistent (i.e., all items worded positively) and the response scale was simplified. The pharmacology, spectrum of activity, pharmacokinetics, clinical efficacy, adverse events, dosage and administration, drug interactions, and place in therapy of tigecycline are reviewed.

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