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Amiline (Amitriptyline)

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Amiline is a type of drug called a tricyclic antidepressant. These drugs were originally developed to treat anxiety and depression, but when taken at a low dose they can reduce or stop pain. Amiline works by increasing the amount of serotonin your brain makes.

Other names for this medication:
Amicon, Amidez, Amiline, Amimax, Amitone, Amitop, Amitrac, Amitrip, Amitriptyline, Amitrol, Amitryn, Amity, Amize, Amrea, Amsha, Amypres, Anitryp, Aptric, Arpidox, Bluneel, Cotrip, Eliwel, Goldep, Latilin, Latiln, Libotryp, Libral, Limbitrol, Lodep, Maxitrip, Mitrip, Nextrip, Psycomer, Raitrip, Ristryl, Triplent, Trixide, Typlin, Typteez, Vanatrip

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Also known as: Amitriptyline


Elavil (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Elavil is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Elavil dosage information


If you overdose Amiline and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amiline overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amiline are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Elavil if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Elavil if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Elavil is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Elavil is not approved for use by anyone younger than 12 years old.

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Finally, curcumin was able to effectively block histone hyperacetylation in both PC3-M prostate cancer cells and peripheral blood lymphocytes induced by the histone deacetylase inhibitor MS-275. The molecules of the 3-nitro isomer are linked into a three-dimensional framework by a combination of C-H...O and C-H...I hydrogen bonds and aromatic pi-pi stacking interactions, while molecules of the 4-nitro isomer are linked into sheets by a C-H...O hydrogen bond and a two-centre iodo-nitro interaction. Multiple Pathological Ocular Findings in a Patient With PHACE Syndrome. This review will recount recent advances in the development of therapeutic approaches for inhibiting and treating the development of diabetic end-organ damage. Apparent encephalocele in twin fetus papyraceus with twin-reversal arterial perfusion. There must be an adequate distribution and supply system to ensure easy availability of the product.

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Fluorescence and morphology modulation in a photochromic diarylethene self-assembly system. The results strongly suggest that voriconazole induces selective and reversible dysfunction of the retinal ON-bipolar cells in both the rod and cone pathways in monkeys. A simple, non-invasive method for recording the tail-skin temperature during conventional tail-flick testing is described. Strains harboring double mutant combinations were constructed and characterized for Ars activity and ars mRNA accumulation. Many patients with RA are unresponsive to or intolerant of conventional therapy or the limited therapeutic options available. The CM functional characteristics can be quantified by phenotype assays, including electrophysiological, optical, and/or mechanical approaches implemented in the past decades, especially when used to investigate responses of the CMs to known stimuli (eg, adrenergic stimulation). Is symptomatic atherosclerotic cerebrovascular disease a risk factor for normal-tension glaucoma?. Morphometric changes in the epiphyseal plate of the growing and young adult male rat after long-term salmon calcitonin administration. Immunological phenotyping gives a more detailed subclassification and may add information on the stage of differentiation of the leukemic cells. We characterize the dynamics leading to this effect and contrast it to the behavior of a more simple associative memory network in which noise-mediated categorization fails.

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Multi-transgenic pigs expressing three fluorescent proteins produced with high efficiency by sperm mediated gene transfer. Attitudes towards induced abortion in Peninsular Malaysia--a Guttman scale analysis. The MYH9/APOL1 region and chronic kidney disease in European-Americans. Among nonbinge drinkers, deficits in emotion regulation strategies were not associated with drunk texting. To develop non-toxic antifoulants based on isocyanoterpenoids, especially 3-isocyanotheonellin, a total of 36 isocyano compounds have been synthesized. The theory provides the reflection, including the amplitude and phase, of radially polarized surface plasmon waves from the end faces of the aperture with a significant departure from the perfect electric conductor case due to plasmonic effects. Almost all women with a record of negative or inadequate smear(s) correctly interpret the result and do not self-report an abnormality. Facile chemical synthesis of W-Ag and W-Cu nanocomposites at low temperature. This preliminary study indicates that patients on both continents may have similar reactivity and suggests that an intercontinental study group could be established to advance our understanding of the pathogenesis of OP and the biology of anti-alpha6 integrin autoantibodies.

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Erythrocyte - endothelial cell adherence in sickle cell disease, diabetes mellitus, and falciparum malaria: adverse effects reversed with piracetam. In this series, several preoperative factors influencing the outcome in surgically treated patients with carpometacarpal osteoarthritis of the thumb were analyzed. Treatment of cells with chemical inhibitors of PI 3-kinase and mammalian target of rapamycin blocked protein synthesis and cell growth while decreasing the phosphorylation of 4E-BP and increasing the binding of 4E-BP to eIF4E, consistent with the notion that 4E-BP1 phosphorylation and eIF4E function are required for hypertrophy. Noncentral camera models are dealt with and results are shown for catadioptric cameras with parabolic and spherical mirrors. Hernia Through the Esophageal Opening of the Diaphragm: Observations on a Case of Right-Sided Hernia.

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During the first day after the explosion, the Chornobyl accident of April 26, 1986 exposed a few hundred emergency workers to high dose levels ranging up to 16 Gy, resulting in acute radiation syndrome. These data suggest that of the common bile salts, the more hydrophobic bile salts stimulate bile flow and cation secretion better than the more hydrophilic bile salts, whereas ursodeoxycholate and ursocholate are more effective than their more hydrophobic 7 alpha-epimers. To gain insight in goblet cell homeostasis and intestinal mucin expression during rotavirus infection, 6-day-old mice were inoculated with murine flagyl dosing c diff rotavirus. The experimental results indicated that highly dispersed polyaniline/AgCl nanocomposites with their size of around 50-100 nm were obtained by the polymerization of aniline and the formation of AgCl at the interface simultaneously. The author examines living arrangements among single persons in the Netherlands, using data from the 1993 Fertility and Family Survey. Choice between signaled and unsignaled food schedules was assessed in two experiments using a shuttlebox. Delphinidin Prevents Muscle Atrophy and Upregulates miR-23a Expression.

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Cell-based tissue engineering is a potential treatment alternative for organ replacement. GMR-based technology can constitute the magnetic counterpart of microelectrodes in electrophysiology, and might represent a new fundamental tool to investigate the local sources of neuronal magnetic activity. The ankyrin family of adapter proteins is emerging as an intimate player in cardiac excitation-contraction coupling. Using functional magnetic resonance imaging (fMRI), here we demonstrate that sleep deprivation amplifies reactivity throughout human mesolimbic reward brain networks in response to pleasure-evoking stimuli. We have examined the photosensitized splitting of the dimer/oxetane unit in TD-CD/Ox-CD by indole or DMA via an electron-transfer pathway, and observed high splitting efficiencies of the dimer/oxetane unit. This suggests that miRNAs may have acted as equilibrators of gene expression during evolution in an attempt to regulate aberrant gene expression and to increase the tolerance to genome plasticity. Results with screening methods in an investigation of aminoacid metabolism disturbances and urinary excretion of beta-phenylethylamines.

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Management of adult patients with large angle amblyopic exotropia. Effect of twin-to-twin delivery interval on umbilical cord blood gas in the second twins. In contemporary liberal ethics patient autonomy is often interpreted as the right to self-determination: when it comes to treatment decisions, the patient is given the right to give or ultram tabs withhold informed consent. Both values are substantially larger than those found in previous studies in adults. Carbohydrate metabolism and endocrine function in the pancreas remnant after major pancreatic resection. The angiotensin-I converting enzyme (ACE) plays a central role in the renin-angiotensin system, acting by converting the hormone angiotensin-I to the active peptide angiotensin-II (Ang-II). The decomposition of data on children under five years of age to single years of age based on population projections. The effect of torso inhomogeneities on the electrocardiographic body surface potentials in general, and the waveform of the QRS complex in the standard leads in particular, were studied by using an inhomogeneous, numerical model of the torso including the (lower) conductivity of the lungs and the (higher) conductivity of the ventricular cavities. We also studied statistical properties of the optical transport in short chains of resonators and demonstrated that even small disorder results in significant drop of transmission coefficient acompanied by strong enhancement of the radiative losses. A chitosan dispersed system (CDS), which was composed of active ingredient reservoir and the outer drug release-regulating layer dispersing chitosan powder in hydrophobic polymer, was newly developed for colon-specific drug delivery.

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