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Alfam (Ibuprofen)

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Alfam is a non-steroidal anti-inflammatory drug (NSAID). It blocks proteins in your body that cause pain, swelling, and fever. Alfam is available both over-the-counter (OTC) and by prescription. The OTC strength is 200 mg, and the prescription strengths include 400 mg, 600 mg, and 800 mg.

Other names for this medication:
Advil, Answell, Arthophen, Artigesic, Brudex, Bruffen, Bruzen, Bufferin, Buftiz, Calpol, Combiflam, Elbugesic, Emflam, Febrilix, Flamizone, Genpril, Haltran, Ibrumac, Ibuclin, Ibucon, Ibuflamar, Ibular, Ibulite, Iburic, Iburin, Ibuspa, Ibuspan, Ibusynth, Mebufen, Menadol, Methopar, Methoprofen, Nuren, Oxydin, Pyrofen, Rebufen, Robiflam, Romet, Rufen, Sugafen, Tabalon, Tidifen, Tizapam, Tizidal, Topgesic, Treza

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Also known as: Ibuprofen


Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (osteoarthritis, rheumatoid arthritis, or juvenile arthritis), such as inflammation, swelling, stiffness, and joint pain. This medicine does not cure arthritis and will help you only as long as you continue to take it .

In addition, ibuprofen can be used to treat fever, menstrual cramps, and other conditions as determined by your doctor .

This medicine is available both over-the-counter (OTC) and with your doctor's prescription .


This section provides information on the proper use of a number of products that contain ibuprofen. It may not be specific to Children's Motrin Bubble Gum Flavor. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients .

When used for severe or continuing arthritis, this medicine must be taken regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine .

To lessen stomach upset, you may take this medicine with food or milk .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets and suspension): For fever: Children over 2 years of age—Use and dose must be determined by your doctor. Children 6 months of age up to 2 years—Dose is based on body weight and body temperature, and must be determined by your doctor. For fever lower than 102.5 °F (39.2 °C), the dose usually is 5 milligrams (mg) per kilogram (kg) (about 2.2 mg per pound) of body weight. For higher fever, the dose usually is 10 mg per kg (about 4.5 mg per pound) of body weight. The medicine may be given every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For menstrual cramps: Adults—400 milligrams (mg) every four hours, as needed. Children—Use and dose must be determined by your doctor . For mild to moderate pain: Adults and teenagers—400 milligrams (mg) every four to six hours, as needed. Children over 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose usually is 10 milligrams (mg) per kilogram (kg) of body weight every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For osteoarthritis and rheumatoid arthritis: Adults and teenagers—1200 milligrams (mg) up to 3200 mg per day divided into three or four equal doses. Children—Dose is based on body weight and must be determined by your doctor. The dose usually is 30 milligrams (mg) to 40 mg per kilogram (kg) of body weight per day, divided into three or four doses. Infants younger than 6 months of age—Use and dose must be determined by your doctor .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Children's Motrin dosage information

Side effects

The most common side effects associated with Alfam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Ibuprofen can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use Motrin PM just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Motrin PM, especially in older adults.

You should not use this medicine if you are allergic to diphenhydramine or ibuprofen, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

heart disease, high blood pressure; a heart attack, stroke, or blood clot; stomach ulcers or bleeding; a breathing problem, such as asthma, emphysema, or bronchitis; liver or kidney disease; glaucoma; enlarged prostate or problems with urination; or if you take aspirin to prevent heart attack or stroke.

Ask a doctor before using this medicine if you are pregnant or plan to become pregnant. Taking ibuprofen during the last 20 weeks of pregnancy may result in serious kidney problems in the unborn baby.

Ask a doctor before using this medicine if you are breastfeeding.

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ALLERGIC DISORDERS OF UPPER RESPIRATORY TRACT BY SAW DUST OF THUJA STANDISHII. Treatment to improve self-awareness in persons with acquired brain injury. The 5-HT2A receptor potassium-chloride cotransporter 2 signaling pathway in a rat incision pain model. The contribution of proteomics to the characterization of physiological modifications occurring during human development is presented. Improvements in the technique and instrumentation used in hair transplantation have led to the production of better grafts, a more natural hairline, a greater number of grafts from a donor site, the effective control of postoperative bleeding, and the reduction of large areas of baldness prior to hair transplantation. We anticipate that the method presented in this paper and the results of these simulations will be a starting point for further investigation of this topic.

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Risk Factors for Glaucoma in a Cohort of Patients with Fuchs Heterochromic Iridocyclitis. To evaluate the influence of the therapy with high-dose corticoids on the clinical and laboratory evolution of HELLP syndrome. More than half of children had enteric carriage of a clinically-relevant form of antibiotic resistance on admission to public-sector hospitals in urban Zimbabwe. In general, all urine samples containing the cytotoxic agents studied were mutagenic because of the presence of the parent compound, except cyclophosphamide which requires activation and therefore an active metabolite was the major mutagenic constituent in the urine sample. We conclude that 2 different mechanisms, characterized by a different response to therapy, may be associated with the same clinical picture of distal swelling with pitting edema in patients with psoriatic arthritis. Control of supraventricular tachycardia by VVI pacing in a patient with drug-induced enhanced atrioventricular conduction.

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High immune responses were generated in mice immunized by proteins from Bifidobacterium bifidum and Bifidobacterium longum. Thus, physical exercise has been established as a low-cost, safe, and effective way to manage NPP conditions, but the exact mechanisms underlying such exercise-induced hypoalgesia (EIH) are not fully understood. epidermidis, beta-hemolytic streptococcus, rarely gram-negative flora and candidae were most often isolated in the ailing children. There were significant differences in multiple variables between patients with or without such disease. Increasing polymethylmethacrylate permeability by adding fillers has been suggested to increase antibiotic elution but the resulting increase in permeability has not been assessed directly. This histopathological lesion may be caused by a primary podocyte injury (idiopathic FSGS) but is also associated with other pathologies (secondary FSGS). The infrared and INS spectra together show that chemisorbed methoxy is the only surface species present. This study aimed to investigate the osteogenesis capacity of rat tendon-derived stem cells TDSCs (rTDSCs) in normoxic and hypoxic cultures, and to study the role of ERK1/2 signaling pathway in this process. A visual perception experiment was conducted to determine the chromatic aftereffects of viewing a yellow-green field that simulated the display of current night vision goggles. Paraphenylenediamine, a contact allergen, induces oxidative stress and ICAM-1 expression in human keratinocytes.

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Effects of zinc on hepatic antioxidant systems and the mRNA expression levels assayed by cDNA microarrays in rats. In particular, the recognition of bitter taste prevents animals from feeding on harmful substances. However, more sophisticated techniques and highly sensitive devices are required, to manage smaller volume samples obtained with this recent method. We demonstrate that the replication-dependent histone gene family is a genic source of imodium ad liquid dosage ping-pong dependent piRNAs and that histone-derived piRNAs are dynamically expressed throughout the cell cycle, suggesting a role for the piRNA pathway in the regulation of histone gene expression. We propose that this anomaly represents a new variant of coronary artery anomaly.

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Two hundred and seventy-five patients gave consent and attended for reassessment. Programs can use these findings to address barriers and improve the integration of research throughout residency training. CALCIFICATION OF THE AURICULAR CARTILAGE IN A PATIENT WITH HYPOPITUITARISM. This quasi-experimental study in Tokyo suggests that emission control was associated with improvements in both air quality and health outcomes. Building Effective Partnerships Between Vascular Surgeons and Podiatric Physicians in the Effective Management of Diabetic Foot Ulcers. Our objective was to assess the pain reduction at various sites and safety of ropivacaine-epinephrine flap injection in BABA thyroidectomy. Five cases showed the Armanni-Ebstein lesion, i.e., clear glycogen-filled cells limited to the pars recta of the proximal tubules. In vitro marrow culture studies failed to predict clinical response to Ara-C.

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