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Alcalm (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alcalm, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alcalm is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aleez, Alltop, Alparazole, Alpracon, Alpramax, Alprocalm, Alsert, Alzoft, Alzotime, Anilam, Anlzium, Axnil, Balmusa, Depflu, Fluprax, Indolam, Mentolift, Parazolam, Plxna, Pronil, Propnix, Proprazolam, Prozolam, Tenan, Tenlax, Visram, Zeftra, Zepro, Zolent

Similar Products:
Cordarone, Asacol, Chloromycetin, Levothroid, Amaryl

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Xanax dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alcalm are:

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A retrospective multivariate analysis of 37 clinical, biochemical, and hematological data was performed in 107 cases of primary myelodysplastic syndromes (MDS) in order to recognize their prognostic significance. MRI/US FTB detected more CSPC using fewer cores compared with random biopsy. Strains of methicillin-resistant Staphylococcus aureus (MRSA) from Australia and the UK were compared by digesting their chromosomal DNA with the low-frequency-cutting restriction enzyme SmaI and separating the restriction fragment length polymorphisms (RFLPs) by contour-clamped homogeneous electric field (CHEF) electrophoresis. We demonstrate for the first time that expression of MSY2 is decreased in CF mice. The resultant Le-AP-2alpha mutants exhibited a targeted deletion of AP-2alpha in lens placode derivatives, including the differentiating corneal epithelium. The findings from those studies were then summarised and are presented here. Interaction between a T cell receptor (TCR) and various ligands, i.e.

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Several cases are now known where average Rn levels are very high, and in all of these cases lung cancer rates are well below average. This chemical mechanism of protection is hereby termed chemo-surveillance. Control of steroid receptor function and cytoplasmic-nuclear transport by heat shock proteins. Breast tumors of patients with a germ-line mutation in the BRCA1 or BRCA2 gene have an increase of additional genetic defects compared with sporadic breast tumors. A Potential Alternative to Respiratory Inductance Plethysmography for Children?. Treating Central Catheter-Associated Bacteremia Due to Methicillin-Resistant Staphylococcus aureus: Beyond Vancomycin. Iron responsive-like elements in the parasite Entamoeba histolytica. Molecular hybridizations with PCR-amplified rDNA targets provided an unequivocal means of differentiating vagococci from related lactic acid bacteria (eg. It has rapidly evolved into the most common liver disease seen in the pediatric population and is a management challenge for general pediatric practitioners, subspecialists, and for health systems.

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Controls were identified if they scored zero (never) for snoring, apnea, and gasping on the multivariable apnea prediction index questionnaire immediately following delivery. Whipple disease (WD) is a rare systemic infection caused by the bacteria Tropheryma whipplei. Chemogenetic activation of this circuit reversed these impaired social behaviors. Introduction of Cys residues into the region between residues 28 and 34 resulted in mutants with low activities, due to a combination of reduced affinities for ATP and diacylglycerol and a reduced maximum rate. Honeycomb Boron Allotropes with Dirac Cones: A True Analogue to Graphene.

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In this paper, we gain insight into the design and optimization of plasmonic (metallic) tips prepared with dc-pulsed voltage electrochemical etching gold wires, provided that, a duty cycle is self-tuned. The effect of prenatal and postnatal education on exclusive breastfeeding rates. Our endotoxemic model induces an initial activation of the hypothalamic-pituitary-adrenal axis, followed by a secondary inhibition of adrenal steroidogenesis processes. Models of previously unknown folds again appear to have modestly improved, and several mixed alpha/beta structures have been modeled in a topologically correct manner. Injections of horseradish peroxidase-wheat germ agglutinin (HRP-WGA) were made in ipsilateral parietal cortex adjacent to the sensorimotor cortex ablations or in the contralateral sensorimotor cortex. Retraction of bioprosthetic heart valve cusps: a cause of wide-open regurgitation in right-sided heart valves. The mean follow-up of all transplant recipients was 3.8 years (SD 2.7 years).

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In agreement with previous studies, however, the nine patients who had had tardive dyskinesia for 5 years or less had significantly lower AIMS scores after receiving vitamin E than after receiving placebo. Cauda equina syndromes in ankylosing spondyloarthritis, detected urologically. Suspension with or without exercise did not alter the normal concentrations of collagen, phosphorus, and calcium in either tibia or femur. Therefore, the relative risk for dying in this age group was 4.9-fold when compared with the normal male population aged 30-50 years. Essential components of the Ti plasmid trb system, a type IV macromolecular transporter. They describe the particularities of RSD in children compared with RSD in adult: differents localizations, X Ray films often normals or showing a local homogeneous osteoporosis, bone scintigraphy with variable result (increased or normal or less uptake of isotope), more rapidly favorable evolution.

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The core macrophage program initiated in pMacs is rapidly diversified as expression of transcriptional regulators becomes tissue-specific in early macrophages. The scarcity of such animal models has hampered progress in glaucoma research. With new studies being published on mortality differentials between native and foreign-born populations in the Nordic countries, specific risk patterns have begun to arise. Immunologically active polysaccharides from Nocardia asteroides and Nocardia brasiliensis. Malarial antigen and other soluble by-products of the malarial parasites, presumably present in spent culture medium, did not interfere with the inhibitory role of C3b inactivator. QUALITY OF PROTEIN IN MIXTURES OF ALGAE, NONFAT POWDERED MILK, AND CEREALS. To compare short-term results of autologous pubovaginal sling and synthetic transobturator (TOT) SAFYRE sling in the treatment of female stress urinary incontinence (SUI). These studies showed that synthesis of the enzyme subunit took place when ammonium-grown cells were nitrogen-starved and this was stimulated by subsequent addition of nitrate. While many studies have been conducted on LL-37, to date little is known about the functional receptors for LL-37-induced human mast cell activation, in particular in terms of the release of de novo synthesized mediators. CaMKII inhibition increased Bim protein and messenger RNA levels.

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Seroepidemiological survey of hepatitis E in Hong Kong by recombinant-based enzyme immunoassays. There are two concepts (mutation-selection balance and balancing selection) which are based on the phenotypic differences between alleles. At least 4 MuV genotypes were identified in the United Kingdom between 1995 and 1998 by direct sequencing of 26 PCR amplicons from a variety of specimens. Preoperative and postoperative risk factors for 30-day mortality following a hip/pelvis fracture were found: ASA classification, ascites, disseminated cancer, dyspnea, functional status, history of congestive heart failure (CHF), history of chronic obstructive pulmonary disease (COPD), a recent blood transfusion, and the postoperative complications: pneumonia, myocardial infarction, stroke, and septic shock. Comparison of outcomes of phase II studies and subsequent randomized control studies using identical chemotherapeutic regimens. Angiology as a most important specialty and an integral part of internal medicine. This case supports the high corrosion resistance and biocompatibility reported for CoCrMo alloys in the literature and the loss of these properties due to inadequate processing.

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In this work, we review recent advances toward understanding how cells transmit growth control and developmental signals, and interdigitate cellular physiology, to regulate HSF function. Insecticidal proteins developed for in-plant protection against crop pests undergo extensive safety testing during the product development process. Differentiation of Boophilus decoloratus and Boophilus microplus. ChIP-sequencing experiments using an anti-O-GlcNAc antibody revealed significant chromatin enrichment of O-GlcNAc-modified proteins at the promoter of the transcription factor MYBL1, which was also characterized by the presence of H3K27me3. Abecarnil, a beta-carboline, is thought to act as partial (low efficacy) and/or subtype selective agonist at central BZ receptors. colorata were studied to assess the possible effects of concerted evolution in natural hybrids. Influence of hunger on the expression of discriminative appetite by the rat (first published in French in 1960). Our results show that the densities of the overall (synaptophysin immunoreactive) and CGRP-immunoreactive innervation is constant during the post-natal development of the gland. For many complex systems containing proline-rich sequences, multiple binding modes have been found by theoretical and/or experimental studies.

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Support for Offering Sexual Health Services Through School-Based Health Clinics. The late functional results of one-side endoprosthetic arthroplasty in 35 patients, supplemented with telemetric examination of temporal parameters of gait, have been presented. Inhibitory synaptic input to edge cells during fictive locomotion. Chronic ventricular pacing at an output of 1.6 V at 0.6 msec is safe and effective when using a steroid eluting lead and potentially has implications for pacemaker longevity. The cells were divided into six groups according to the number of microvilli and/or microridges present on their surface. Despite a positive correlation between phonotactic probability and neighborhood density, nonsense words with high probability segments and sequences are responded to more quickly than nonsense words with low probability segments and sequences, whereas real words occurring in dense similarity neighborhoods are responded to more slowly than real words occurring in sparse similarity neighborhoods. Using electron microscopy, an increase in the beta-cell mitochondrial volume in islets exposed to palmitate was observed. As compared to healthy individuals, DM1 patients showed a delayed central motor conduction time and an abnormal sensory-motor plasticity, with no alteration of cortical excitability. This study evaluates the hemodynamics of tilting disc valves under this condition. The techniques augment the description of the correlation obtained with conventional cross-correlation measures.

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Studies involving LAT mutants and reconstitution experiments strongly implicate LAT in playing a critical role in T cell activation. The whole open reading frame of p53 was determined by reverse transcription-PCR sequencing. These particles, of about 100 A in diameter with a molecular weight of approximately 1.5 million, are by far the simplest functional naturally occurring photosynthetic electron-transport units thus far described. The inhibitory effect in vitro of salvia miltiorrhiza and tetramethyl pyrazine on the growth of fibroblasts. A significant age related increase in serum IgE concentrations was observed in these patients. A specimen of intact muscle fibers was excised from the external intercostal muscle of one of the patients. In bilateral macular surgery cases, only the first eye was included. Stratification showed lower TG and longer time picking up a pencil only for those above 84 years.

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This is a retrospective study of patients presenting with clinical left varicocele to the male infertility unit at a teaching hospital in Qatar. Peritoneal dialysis is the preferred form of dialysis during pregnancy because it is continuous and lacks the wide variation in chemistries, weight and blood pressure, and avoids the use of anticoagulation necessary during hemodialysis. Serial studies of bone marrow megakaryocyte ploidy after the induction of acute, severe thrombocytopenia (platelet count, less than 0.05 X 10(6) microL) demonstrated no detectable change in the ploidy distribution at 12, 24, and 36 hours after the onset of thrombocytopenia. The primate-specific N-BLR is a novel molecular contributor to the complex mechanisms that underlie metastasis in colorectal cancer and a potential novel biomarker for this disease. Behavioral effects and general pharmacology of 4-(5-chloro-benzofuranyl-2)-1-methylpiperidine HC1, an antidepressant inhibiting both monoamine oxidase A and 5-hydroxytryptamine uptake. We report a 69-year-old woman who presented with a hardened plaque on the axilla. Rapid fabrication of support-free trimetallic Pt53Ru39Ni8 nanosponges with enhanced electrocatalytic activity for hydrogen evolution and hydrazine oxidation reactions.

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There was a significant decrease in complement-dependent antibody-mediated cytotoxicity when sera from the diabetic children were treated with either ethylene glycol tetra-acetic acid or ethylene diamine tetra-acetic acid. The World Health Organization MONICA Project (monitoring trends and determinants in cardiovascular disease): a major international collaboration. Lipid metabolism has been suggested to be associated with clinical outcomes of renal cell carcinoma (RCC). This suggests that we should not expect synergistic epistasis to be widespread in nature and hence that the mutational deterministic hypothesis for the advantage of sex may not apply widely. Gold particles with diameters of several tens of microns were mixed with MWNTs to mount on the heating element of a specimen heating holder. TIDAL VOLUME, OXYGEN UPTAKE, CARDIAC OUTPUT, AND BODY SURFACE IN THE CAT. There was no significant difference in the TRH-induced hyperthermia between the groups when tested at 13 weeks of age. Each antibody gave different staining when tested on a range of vascular tumours, both benign and malignant. Prospective follow-up of an age-homogenous representative community-dwelling cohort (born 1920-21) in the Jerusalem Longitudinal Cohort Study (1990-2015).

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Single collagen fibrils were seen to cross the bundles, thus forming cross-links between neighboring bundles of collagen fibrils. The smallest observed pre-fission tethers were 60 nm in diameter for both the inner and outer membranes. The capsular contraction around the implant and the buckling are probably sumycin drugs camouflaged by a subpectoral implantation and this presentation should be recognized by the surgeon, especially when considering placement of the cohesive gel implant in a subglandular position. It aims to increase consideration of the theoretical basis of rehabilitation practices. Novel functionalization strategies to improve drug delivery from polymers.

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Diagnostic and pathogenetic significance of determining lactate dehydrogenase isoenzyme activity in various biological media in patients with viral hepatitis. In contrast, PMA has little effect on ICAM-1 gene transcription up to 4 h following stimulation. Computational Analysis of Pumping Efficacy plavix generic price of a Left Ventricular Assist Device according to Cannulation Site in Heart Failure with Valvular Regurgitation. The release rates of indomethacin from microemulsions containing water, isopropyl myristate, lecithin, lysolecithin and alcohol are reported. As the KCl concentration was increased, Kobs decreased thus establishing the salt dependence of the interaction. Three alcohol dehydrogenase genes and one acetyl-CoA synthetase gene are responsible for ethanol utilization in Yarrowia lipolytica. Secondary measures were oncologic outcomes, including regional structural or biochemical recurrence. They support the immediate surgical care in the therapy of injuries caused by foreign body, they deal however with the problems of the later therapy, too. Eight patients revealed a focal hyperoxygenation pattern related to focal CBF increase and three patients showed a focal deoxygenation pattern related to focal CBF decrease.

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The stimulation of THI3 promoter activity was diminished by deletion of THI3, indicative of the autoregulation of THI3. Differential diagnostic considerations using ICD-10 in chronic back pain with special regard to persistent somatoform pain disorder with somatic and psychological factors (ICD-10 F45.41). Soft tissue infections are a common reason for general surgical consultation. CHANGES IN THE SORPTION PROPERTIES OF THE MUCOUS MEMBRANE OF THE GASTROINTESTINAL TRACT OF RATS TO VITAL DYES DURING THE USE OF SARCOLYSINE. Insertion technique, the key to avoiding infusion phlebitis: a prospective clinical trial. The study was performed to determine whether irradiation of the tumor bed alters the propensity of tumors to metastasize, and if so, whether the effect is dependent on the property of tumors to exhibit the tumor bed effect (TBE). We further explored the function and mechanism of S1P in promoting revascularization and protection against thrombosis in this tissue engineered vascular grafts. The DML was measurable in all 30 hands of the reference group, in all 96 hands of the patients by Dantec, but in only 82 hands (52 para que se utiliza el medicamento neurontin 600 mg patients) by Nervepace. Group 3 received an identical bacterial inoculum, followed by a 10-cm midline laparotomy.

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A review on regional convection-permitting climate modeling: Demonstrations, prospects, and challenges. These events need to be tightly regulated in order to ensure optimal activation when required, and minimal signaling in the absence of microbial encounters. Although de-differentiation may occur in adult mammalian cardiomyocytes, it is typically associated with diseased hearts and pathologic remodeling rather than repair and regeneration. The device provided some benefit to performance, although the amounts of improvement varied across tasks and subjects. Improvement was not observed in 2 cases after extracranial-intracranial bypass alone or in 3 cases in which surgical intervention was not undertaken. The aim of this study was to develop the efficient, reliable and fast method for isolation of the d,l-HMPAO, which would provide the ligand with high purity and free from the meso-diastereomer. Some members of the sHsp family are inactive or only partially active under physiological conditions, and transition toward the active state is induced by specific triggers, such as elevated temperature. Is Rivaroxaban Associated With Shorter Hospital Stays and Reduced Costs Versus Parenteral Bridging to Warfarin Among Patients With Pulmonary Embolism?. We presented the clinical and radiological features of our patient and discussed them with reference to the literature.

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The dose of ciclosporine-A (CSA) for long-term treatment of nephrotic syndrome remains unclear due to the chronic nephrotoxicity of CSA. Rearrangement of the neoplasia-associated gene HMGIC in synovia from patients with osteoarthritis. The concept of a spindle matrix has long been proposed to account for incompletely understood features of microtubule spindle dynamics and force production during mitosis. The study population included 1314 men who underwent radical prostatectomy at the Tampere University Hospital during 1995-2009. A significant increase in IgA class antibodies against porcine eye muscle antigens was seen concomitant with development of ophthalmopathy. The Hantaviruses, etiologic agents of hemorrhagic fever with renal syndrome: a possible cause of hypertension and chronic renal disease in the United States.

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Until the final proposal and in order not to miss the opportunity to boost pertussis immunity in children who were vaccinated as infants at the reintroduction of pertussis vaccination, the Board now recommends the Swedish municipalities as an interim measure to include pertussis in the current school booster against diphtheria and tetanus at 10 years of age with a full dose vaccine. Behavioral and Nondirective Guided Self-Help for Parents of Children with Externalizing Behavior: Mediating Mechanisms in a Head-To-Head Comparison. Viable organisms were recovered after an exposure of 40 min at ambient temperature. Injectable nano-carriers have important potential applications as in suprax site-specific drug delivery. The physical effects of temperature on biological membranes are reviewed.

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Performance of four hearing-impaired subjects showed that filter effects were related both to the frequency spectrum of the noise and to the distribution of speech information by frequency. Evaluating the pregnant cervix uteri by ultrasound with computer-assisted texture analysis. Areas covered: In this review, we will present the pharmacokinetics and dynamics of mepolizumab in addition to efficacy and safety data. No symptom parameter was significantly altered by placebo therapy. LOH was scored when the tumor allele intensity ratio (tumor allele 1/tumor allele 2) divided by the normal allele intensity ratio (normal allele 1/normal allele 2) was either less than 0.71 (tumor allele 1 LOH) or greater than 1. Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.

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Predictors for extraintestinal infection in Salmonella enteritis in Thailand. Trait Variance and Response Style Variance in the Scales of the Personality Inventory for DSM-5 (PID-5). We aimed to characterize how this structure exists in 3D and changes with age. However, fast responses have not been obtained because effective control is achieved by an integral feedback that accompanies a time delay necessary for error accumulation. Cosmetic results are generally excellent but may be compromised by previous surgery in recurrent lesions or tumor destruction of normal tissues in advanced lesions. Traditional low-alcoholic and non-alcoholic fermented beverages consumed in European countries: a neglected food group. In women who have received prior radiotherapy and are often considered for palliative treatment, interstitial brachytherapy is a potentially curative option. Persons labelled as witches-mostly older women-may be bullied, ostracised, beaten, stoned, burned, even killed. A small, but significant number of colonoscopies are converted to flexible sigmoidoscopies at the time of the procedure. Massive Hemolysis Causing Renal Failure in Acute Hepatitis E Infection.

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There is some question whether continuous topical treatment with acyclovir to sites of recurrent herpes will sometimes prevent erythema multiforme. stearothermophilus is a standard assay noted for its sensitivity to penicillins. The primary form occurs idiopathically, with meconium aspiration syndrome and with hypoplasia of the lung and is characterised by excessive muscular hyperplasia of pulmonary arteries. A complete mitochondrial (mt) genome was 16,521 bp comprising 13 protein-coding genes (PCGs), 22 tRNA genes, 2 rRNA genes, and 1 non-coding region (NCR). In this article, we have reviewed epidemiological studies that have been done to look into the relationship of HCV with nonliver solid cancers of the pancreas, thyroid, renal, oral cavity, breast, and lung and nonpancreatic gastrointestinal cancers. The Ala frequency in an Asiatic population (Chinese) was significantly lower than in most European populations. Increased rates of punished responding produced by buspirone-like compounds in rats. The clonality indicates that the tumours are initiated with, and possibly by these abnormalities as predicted by Boveri in 1914.

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