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Adefin (Nifedipine)

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Adefin is used to treat high blood pressure or angina (chest pain). For high blood pressure: Adefin works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart. For angina: Adefin works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it. Your angina attacks will be less severe and less frequent if there is less strain on the heart.

Other names for this medication:
Amarkor, Belnif, Bresben, Calchan, Cardicon, Cardifen, Cardiosol, Cardipin, Cobalat, Conetrin, Corinfar, Farmalat, Glopir, Hexadilat, Nifcal, Nifebene, Nifeclair, Nifedalat, Nifedine, Nifedipino, Nifensar, Niften, Nipidin, Nipress, Nycopin, Pabalat, Siopelmin, Valni, Vasdalat

Similar Products:
Lozol, Furadantin, Astelin, Minipress, Zyrtec, Maxalt, Robaxin, Dilantin, Abhigra

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalat OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Adefin and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Adefin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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More than two sheets of asbestos ribbons in dry state had the ability of compensation for casting shrinkage in heating process. Further studies with a larger sample size are needed to assess the effect of such a program on functional abilities, prevention of risk factors, and recurrent stroke. Use of trimethoprim and sulphamethoxazole in tropical Africa: typhoid fever, salmonella typhi carriage and staphylococcus aureus sepsis. Polyclonal anti-DBP was produced using rabbit by intradermal injections of Escherichia coli-expressed purified recombinant DBP. Molecular cloning, expression and characterization of enolase from adult Haemonchus contortus. Of medical significance, the divergent giActin cytoskeleton is essential and commonly used actin-disrupting drugs do not depolymerize giActin structures. Staphylococcus saprophyticus and Escherichia coli, and the mucosal lining of the human urethra was studied in a tissue organ culture system utilizing 14C-labelled organisms and scanning electron microscopy. Case report: Varicosity of the communicating vein between the left renal vein and the left ascending lumbar vein mimicking a renal artery aneurysm: Report of an unusual site of varicose veins and a novel hypothesis to explain its association with abdominal pain. The concentrations of several substances of various molecular sizes, electrical charge, transport mechanism, etc.

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Typological analysis of demographic changes in the Tuscan communes. A questionnaire was mailed to 462 directors of non-military family practice residency programs in the United States. In this cell we demonstrated that only the smallest micronuclei had an incomplete nuclear envelope. Regiochemistry of neuroprostanes generated from the peroxidation of docosahexaenoic acid in vitro and in vivo. However, the VMH rats continued to drink more of the sugar solutions than did the controls after all atropine treatments, and in three out of four experiments their hyperphagia on the chow diet was not blocked by the atropine. However, the scaling of anaerobic muscle power has not been closely assessed in between-species comparisons of mammals varying greatly in body size. Clinical studies on the use of roxatidine acetate for the treatment of peptic ulcer in Japan. The levels of injury markers in the bronchoalveolar lavage fluid (BALF), collected from rat lungs treated with PEI-1, were no different from that in BALF collected from saline treated rats.

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Studies on relationship between immunodeficiency in HIV-infected people and condition of upper gastrointestinal tract mucosa, prevalence of mycosis and Helicobacter pylori infection. The data available so far suggest that exercise training programs can reduce exacerbation rates and that this effect is achievable by minimal personal assistance. Observations from this study over one month suggest that a significant percentage of pediatric patients successfully managed their asthma with montelukast and their parents were satisfied with their medication, compared to baseline. Here, we present a review of the available data concerning the relationship between the rates of skeletal muscle blood flow and oxygen consumption (V(O2)). coli RecA protein by interaction with DNA and nucleoside triphosphate. By conventional light microscopy, a reduced number of Paneth cells per intestinal crypt was found in the jejunal mucosa of patients with untreated or gluten-challenged coeliac disease as compared with histologically normal control specimens. Pharmacokinetics and normal scintigraphic appearance of 99mTc aprotinin. We developed a simple method to produce patterned catalysts for the growth of carbon nanotubes (CNTs) on Si substrate using laser irradiation of Ni nitrate. In addition to its effects on lymphocytes, mycophenolic acid (MPA) may inhibit the allostimulatory capacity of dendritic cells (DC) via unknown mechanisms. Influence of cirrhosis on production of atheroarteriosclerosis and thromboarteritis with vitamin D and dietary cholesterol.

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Although certain sera from culturally proven cases of blastomycosis, coccidioidomycosis, and cryptococcosis reacted with the purified Histoplasma antigens, preliminary evaluation indicated that the immunofluorescence technique may be of value as a screening procedure for the serodiagnosis of histoplasmosis. Clinical data on treatment with 2-acetamido-4-(5-nitro-2-furyl)-thiazole in acute infectious enteritis in infants. Influence of additional working memory load on emotional face recognition was studied in healthy adults. The cylinder power of toric IOLs was determined by an online toric calculator with keratoscopy measurements obtained using Scheimpflug corneal imaging. Moreover, we used them to measure the ability of particles of different sizes to access the tumor. Early results indicate that the material is tolerated well in the eyelid, but the problem of early slippage remains. Two patients with ulcerative colitis and a past history of allergic reactions to sulfasalazine had similar reactions when treated with 5-aminosalicylic acid. Superordinate shape classification using natural shape statistics.

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Phylogenetic relationships of TyrA domains were evaluated in the context of combinatorial patterns of specificity for the two substrates, as well as the presence or absence of a variety of fusions. Glycation by glyoxal and methylglyoxal resulted in histone cross-linking in vitro and induced oxygen-dependent cleavage of plasmid DNA, which was partly suppressed by the hydroxyl scavenger mannitol. Validation of English-language versions of three scales measuring attitudes towards smoking, smoking-related self-efficacy and the use of smoking cessation strategies. IMOs containing N-Me-cytosine or N-Me-guanine pepcid 20 mg tablet cpt code modification showed activity in mouse spleen cell cultures, in vivo in mice, and in human cell cultures. These plugs are shuttled back and forth along the channel, sweeping over microarray probes while re-circulation mixing occurs inside the plugs. Behavior of central and peripheral chemoreflexes in heart failure. Especially a slight elevation of CRP and normal WBCC make the prevertebral tendinitis more likely.

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Effect of diplodiatoxin (Stenocarpella maydis) on some enzymatic profiles in male and female rats. Participatory action research provided a flexible, socially, and culturally adaptable framework to guide this international research project. Mitochondrial DNA (mtDNA) mutations occur in head and neck squamous cell carcinoma (HNSCC) and are most frequently detected in the displacement-loop (D-loop) region. Finally, these surfactants were used to create neutrally buoyant microemulsions with a PCE DNAPL. If the protein needs to maintain electroneutrality, then 2 protons will be bound when the BNC is reduced by 2 electrons in the reductive half of the reaction cycle. Eight of the remaining cDNA sequences showed sequence homology to those previously reported such as ribosomal protein S23, MLN137, ACTN4, transforming growth factor and G protein gene. Previous studies have shown that miR-520b/e acts as a tumor suppressor in several tumors. Nevertheless, since early in the epidemic, people living with HIV/AIDS have spoken out to present their personal perspectives on living with HIV and to challenge perceptions about who can and cannot become infected. Our findings suggest that MM-especially in its pleural localization-is often misdiagnosed in eastern China.

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However, the addition of 3-methylglucose, an analog of glucose that is not phosphorylated, did not result in repression of either MS or ICL. It consists of a flexible anchor at the front and a lockable bracket at the rear. To describe the accident details and the effects of bicycle-spoke accidents on the physical and psychosocial functioning of children. Peripheral vascular disease in end-stage renal disease patients. Early results of the present study suggested that surgical AVR with a sutureless valve is associated with a good hemodynamic performance and an improved early outcome. Few epidemiological studies evaluated associations between perinatal complications and maternal mood at the early postpartum period and the findings are inconsistent. The activity and antigen of plasma F were measured by photometric test and enzyme-linked immunosorbent assay, and rocket-electrophoresis, respectively. A monthly systematic bacteriological report improves accuracy of identification of hospital-acquired infections in an ICU. To investigate the effect of endothelial progenitor cells (EPCs) labeled by carboxy fluorescein diacetate succinimidyl ester (CFSE) on murine oxygen-induced retinopathy (OIR) by intravitreal transplantation.

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There was neither a significant correlation between the increase from the basal to maximum GH and GHRH after TRH injection in the 12 cancer patients nor a reciprocal relationship between the increase in GH and TSH after TRH injection in the 76 cancer patients. To evaluate the effects of acupuncture for treatment of climacteric syndrome. Due to its antioxidant and anti-inflammatory properties, hydrogen gas (H(2)) has protective effects on a variety of organs from damage induced by ischemia/reperfusion (I/R). In a further experiment, six SC strains--three from CBPP and three from goats--all gave weak partial cross-protection against subspecies capri. An experiment was prepared in a rat model in which the iliolumbar veins were utilized as the draining veins, and musculocutaneous flaps, 4 x 10 cm in size, were created. A probability model to characterize the pattern of total number of migrants from a household has been developed. Isolation and characterization of a new immunomodulatory protein, ling zhi-8 (LZ-8), from Ganoderma lucidium. An exception wasfound in a B-cell lymphoma (Q254) where the tumor cells contained a single integrated feline immunodeficiency virus genome. When the level of FA was 1000 mumol/L, no any tailed cell could be observed, the migration of DNA was inhibited completely even H2O2 was used. Simvastatin initiated early after heart transplantation: 8-year prospective experience.

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Ort1p/Arg11p is a member of the mitochondrial carrier family (MCF) essential for ornithine export from mitochondria. Water and electrolyte metabolism during extracorporeal circulation. As an alternative strategy, we rationally designed a peptide coating able to bind transferrin on suitable pockets not involved in binding to TfR is celebrex a prescription drug in australia or iron by using an iterative multiscale-modeling approach coupled with quantitative structure-activity and relationship (QSAR) analysis and evolutionary algorithms. Sensitized TiO2 nanocomposites through HMME linkage for photodynamic effects. Two healthy baboons were implanted intraperitoneally with microencapsulated islets through mini-laparotomy and observed at 76 d after implantation. Age-related macular degeneration: analysis in two ophthalmological centers in Pernambuco-Brazil. Immunological and serological studies of infectious mononucleosis in patients in Kyusyu, Japan and the U.S. On the other hand, the NADPH-linked component was less sensitive to heat, urea and dicoumarol. Finally, operative procedures such as ovarian drilling, coagulation of endometriosis, lysis of adhesions, treatment of ovarian cysts, and salpingostomy may be performed via THL.

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PON1 arylesterase activity was significantly higher in girls than in boys. Processing can be restored in CCCP-treated cells and in valinomycin-treated spheroplasts by dilution of the treated cells in fresh medium. Here, we report three sets of 4-phenylpiperazine stereoisomers that differ considerably in efficacy: the (R)-enantiomers are antagonists/weak partial agonists, whereas the flagyl dosing bv (S)-enantiomers are much more efficacious. Equal numbers of patients were withdrawn from the indoprofen and ibuprofen groups but the reasons for withdrawal were different. Hemorrhagic fever is endemic in certain regions of the Balkans, and this preliminary report suggests the importance of investigating the endocrine status in every patient who survived HFRS. Older black women differ in calcium intake source compared to age- and socioeconomic status-matched white women.

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Both p21 feldene gel vs voltaren and p27 were rapidly increasing at the first 12 hours after exposed to the agent, then decreasing slowly in the 24, 48 hours, and increasing again in 72 to 144 hours. rRNA-based profiling of bacteria in the axilla of healthy males suggests right-left asymmetry in bacterial activity. We describe the modification of the epsilon-amino group of lysine contained in a test peptide with stable fluorescent adducts derived from monofunctional aldehydes occurring in cigarette smoke and malonaldehyde, a product of lipid peroxidation. Antioxidant effects of lycopene in African American men with prostate cancer or benign prostate hyperplasia: a randomized, controlled trial. Virus-induced gene silencing (VIGS) of the LMI1-like gene in an okra variety was sufficient to induce normal leaf formation. We suggest that the transition from thyroid to carcinoid is accomplished through an intermediate stage of calcitonin-positive cell proliferation. This leads to the production of an N-terminal fragment, called fragment N, that activates the Ras-PI3K-Akt pathway and that promotes cell survival. Comparison of the Oxi/Ferm and N/F systems for identification of infrequently encountered nonfermentative and oxidase-positive fermentative bacilli. Increasing the number of trainees in general surgery residencies: is there capacity?. A review of 83 cases, and a comparison with those remanded in hospital.

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Being a marker for brain tumour progression and angiogenesis, lysozyme c was highly up-regulated under the combined chemo/radio treatment. The experimental model of acute gastritis such as water immersion restraint (WRS) stress-induced gastric injury is useful tool in examination of pathomechanism of acute gastritis. To compare the effect on outcomes of the route of administration of corticosteroids in acute Vogt-Koyanagi-Harada disease. Quality assurance and quality control measures are considered core elements in future modernisation of medical education in Kosova. Capillary electrophoresis for chimerism monitoring by PCR amplification of microsatellite markers after allogeneic hematopoietic cell transplantation.

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These were the slope (Emax) and the intercept (V0) of the isovolumic end-systolic pressure-volume relationship (ESPVR), the slope of the end-diastolic pressure-volume relationship (Ed), the time to Emax (Tmax), the normalized time to end of activation (A), and the resistive constant (K). The subjects were 134 cost of amoxil women who recently went through menopause. To investigate early and remote results of surgery in patients with recurrent non-small cell lung carcinoma (NSCLC) after previous chemoradiotherapy alone. Progesterone plays a critical role in the menstrual cycle, pregnancy, and sexuality. Social conformity persists at least one day in 6-year-old children.

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To assess the effectiveness of autologous melanocyte transfer by epidermal grafts for lip vitiligo and to review the literature on the surgical correction of lip vitiligo. Relevant papers published between 1970 and January 2002 were identified via the MEDLINE, PUBMED, and EMBASE databases. This study found no significant difference in anterior knee pain and in the function of the patellofemoral joint and the knee in the groups of patients who were tested with the different scales. In the test conditions the fluorescence is proportional to the ketimine concentration from 1 to 200 microM. Biological macromolecules in solvents of variable density: characterization by sedimentation equilibrium, densimetry, and X-ray forward scattering and an application to the 50S ribosomal subunit from Escherichia coli. In this review, the conventional chondrosarcomas are subdivided into central and secondary peripheral chondrosarcomas, based on their different genetic and clinicopathological background. Results suggest a therapeutic benefit for EGFR blockade with erlotinib in patients with biliary cancer. Most of these conditions require close follow-up and timely surgical intervention.

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