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Addos (Nifedipine)

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Addos is a dihydropyridine calcium channel blocker. Addos is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Addos was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Addos works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Addos, Amarkor, Aprical, Atenerate, Calcianta, Calcigard, Cardalin, Cardicon, Cardiosol, Cardipin, Cardules, Casanmil, Coral, Corinfar, Depine, Duranifin, Emaberin, Farmalat, Fedip, Fenamon, Fenidina, Glopir, Hexadilat, Hypan, Macorel, Marivolon, Menoprizin, Milfadin, Myogard, Nidilat, Nifangin, Nifatenol, Nifcal, Nifebene, Nifecard, Nifeclair, Nifecor, Nifedate, Nifedical, Nifedipin, Nifedipina, Nifedipino, Nifelat, Nifensar, Niften, Nilol, Nipin, Siopelmin, Tredalat, Viscard

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalat PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Addos and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Addos are:

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Influence of Manual Screwdriver Design in Combination With and Without Predrilling on Insertion Torque of Orthodontic Mini-Implants. Two milliliters of SonoVue is slowly injected and the pancreas is scanned using the low MI nonlinear imaging mode to visualize the microbubbles enhancement of the pancreas to ensure uniform perfusion of the whole organ. Past reports have suggested that some withdrawal symptoms can present after 1-2 days upon abrupt discontinuation of gabapentin after chronic use within young to middle-aged patients. Phylogenetic analyses were essential in understanding how the outbreaks were related to each other, and in demonstrating that dengue had not become endemic. This investigation was undertaken to determine whether antioxidant vitamins ameliorate the beneficial effects of cardiac rehabilitation and exercise training (CRET) on insulin sensitivity and glucose metabolism in patients with coronary heart disease (CHD). Toxic effects of triethyldodecylammoniumbromide (TEA-C12) on myelinated nerve fibers and blood-nerve barrier in the mouse. Higher sensitivity and greater visual reliability may be obtained at the expense of temporal resolution: the corner frequencies of dark-adapted ocellar photoreceptors were just 4-11 Hz. The results indicate that immunofluorescence may offer an effective method for rapidly and accurately diagnosing bacterial epididymitis in sheep, especially before epididymal lesions are palpable. Effects of cytokines on the immunogenic properties of hepatitis A vaccine. In all, 38 patients were enrolled, of whom 20 had OAT, 15 non-obstructive azoospermia and three Y chromosome (Yq) microdeletions (AZF).

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It is of interest to understand the structural basis for metalloactivated methyl transfer and methylation-dependent enhancement of DNA binding activity. The aim of the present study was to systematically identify the surgical technical errors leading to these complications. Nicotine injections as the conditioned stimulus in discrimination learning. The effect of increasing concentrations of 8-bromo-cGMP on uterine spontaneous contraction was also studied. Effects of vitamin E deficiency on hepatic mitochondrial lipid peroxidation and oxidative metabolism in rats with chronic dietary iron overload. trh gene has been successfully cloned with its sequence analyzed, which prepares the ground for developing gene probe and protective vaccine against Vp. Association between alopecia and response to chemotherapy in patients with Hodgkin lymphoma. Bridging microscopic and mesoscopic simulations of lipid bilayers. Surgery should be as close as possible to displacement in order to minimise mucosal inflammation and to prevent unnecessary manipulation during surgical removal. We did not find an association between sperm morphology and clinical outcomes.

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pastoris expression vector, pBGP1, incorporating an autonomous replication sequence that allows the plasmid to exist as an episomal element. The use of anencephalic fetuses and neonates as organ donors is technically feasible, and xenografts may be. To the best of our knowledge, this is the first description of a flow cytometric protocol that quantifies adhesion of both pure and mixed gut microbial cultures to a differentiated monolayer of Caco-2 cells and that allows to distinguish between viable and dead adhered bacteria. NMR study on 1,2,4,5-tetrasubstituted 3,3,6,6-tetradeuterated cyclohexanes: conformational contributions and 1,3-diaxial and vicinal deshielding effects of amino and alkylated amino groups and their protonated forms. Most families use kerosene, firewood, coal, and cow dung as sources of energy. Synergistic performance of lecithin and glycerol monostearate in oil/water emulsions. Extracorporeal albumin dialysis in acute-on-chronic liver failure: will it stand the test of time?. Fictitious cases were generated during the process, and volunteers participated in the testing.

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Chemotherapy of 5-fluorouracil and leucovorin or levamisole was given intravenously during the first and last week of radiotherapy, and then monthly for about 6 mo. Drosophila S2 cell extract is a good source of enzymes and factors that faithfully recapitulate essential steps in RISC assembly and function. A 28-year old man developed transmural anterior wall myocardial infarction after a car accident despite the absence of external signs of chest trauma. An animal model was developed to observe these effects on the growth and development of the immature spine over a two-year period. Overall, these findings demonstrate that amino acid prodrugs of BDCRB exhibit evasion of metabolizing enzymes (i.e., bioevasion) in vitro and provide a modular approach for translating this in vitro stability into enhanced in vivo delivery of BDCRB. Endoscopic laser surgical resection of advanced squamous cell carcinoma (SCC) often requires division of the tumor into several pieces. It follows our previous paper that identified, through a literature search, the key issues in moving towards EBM in general practice in these areas1. A simple word-matching computer program to code occupation entries from vital records was developed. Participation in these community activities is dependent on the initial health-seeking behaviors of the individual.

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Implications of the findings with respect to excitation energy transfer pathways and rates are discussed. RI anchoring disruptor (RIAD) is a high-affinity competitor peptide that specifically displaces type I PKA from A-kinase anchoring proteins. Certain materials are superior to unaltered cotton in providing a more absorbent fiber--nutrients are efficiently drawn in, concentrating protein between fibers, and thereby creating an ideal physicochemical environment for the amplification of TSST-1 and other toxins. In most cases, episodes of singultus are benign and self-limited. They discuss such subjects as factors involved in the influenza epidemic of 1918-1919, the principal causes of death, and infant mortality and the socioeconomic factors involved.

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The contributions and limitations of studies describing changes in fertility and mortality in relation to certain socioeconomic indicators are examined, and the need for research aimed at permitting explanation of these changes is stressed. Systematic study is required to determine whether a basal dietary intake of arginine is required to maintain immune function during health and how much arginine is required to meet metabolic requirements during periods of growth or stress. A new topically applied morphine gel for the pain treatment in patients with chronic leg ulcers: first results of a clinical investigation. Selective O2 oxidation of air-sensitive lanthanocene thiolates and thioether chelate. The VL-linker-VH-CL constructs result in significantly lower dimerisation levels compared to the VH-linker-VL-CL antibody constructs.

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Preliminary identification and analysis of different points related with response to interferon-alpha in HBV post-transcriptional regulatory element. Several episodes of acute intestinal ischaemia were later developed requiring bowel resections of which histological examination showed vascular occlusive fibrotic changes without active vasculitic lesions. Monolayer freeze-fracture autoradiography: origins and directions. A comparison of the number of post-transfusion hepatitis cases occurring before and after the commencement of routine testing for HBAg showed a marked reduction in reported cases in 1971. This chapter outlines the steps and the R scripts that can be used for performing permutation analysis with false discovery rate control via the Benjamini-Yekutieli method. Opportunities for applied behavior analysis in the total quality movement. The Affymetrix microarray containing 169 autosomal SNPs developed for forensic application was applied to our practical case for kinship analysis that had remained inconclusive due to partial STR profiles of degraded DNA and possibility of inbreeding within the population.

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We illustrate our methods using two randomized trials testing growth factors in febrile neutropenia. The aim of this study was to explore the associations between warfarin treatment, INR, and time from admission to surgery. This study uses a large national sample, a wide range of predictor variables, and multivariable statistical techniques to estimate more reliable similarities and differences between note leavers and other suicides. These results reveal that UVRR spectroscopy shows promise as a direct method for detecting 8-oxo-dG. The study provides further support to the hypothesis that service screening with mammography reduces the risk of breast cancer mortality. Cytokine-mediated inflammatory cell recruitment into the brain is a critical step in the response to diverse insults, including infection, trauma, and stroke. A decrease in urinary cortisol excretion during the night of HDBR was noted. Mechanism of ToxT-dependent transcriptional activation at the Vibrio cholerae tcpA promoter.

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The defects in endocytosis, actin cytoskeleton, and morphology of arp2 are also suppressed. Tetrahydrofolate (H4folate) derivatives are chemically analogous to tetrahydropterins and dihydroflavins, and like these compounds can be oxidized readily. Little is known about prokaryotic homologs of Cu,Zn superoxide dismutase (SOD), an enzyme highly conserved among eukaryotic species. Growth inhibition by DDATHF was prevented by addition of both thymidine and hypoxanthine, but not by thymidine alone. The groups containing NTLR with the highest percentages of circulating T-cells also contained animals with both moderate and severe M. Biocompatible and biodegradable scaffolds seeded with living cells are used to create functional tissue for load-bearing bone reconstruction. Prevalence of hepatitis A across various countries in the Middle East, African and Eastern European countries. Bacterial resistance to quinolones/fluoroquinolones has emerged rapidly and such resistance has traditionally been attributed to the chromosomally mediated mechanisms that alter the quinolone targets (i.e. The enhancement of nonheme iron bioavailability by beef protein in the rat. To address the lack of educational preparation of GP-preceptors, and in accordance with the stringent teaching and assessment standards of the Australian Medical School Accreditation, a tripartite approach was taken to educational skills development among rural GP-preceptors.

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The latter include various data mining tools, like virtual screening filtering experiments using pharmacophore models, docking studies, and neural networks, which help to establish a relationship between chemical structure and biological activity. The ability to induce HSP72 is significantly higher in zinc L-carnosine compared with zinc sulfate based on molecular concentration in vivo. Recombination is also relatively common and important for generating protein variants. As a consequence, sequence-based typing of these genes is time-consuming. Gap junctions and intermediate junctions are observed between these fibroblast-like cells, and also between them and smooth muscle cells. The confusion caused by advertising glyburide dose range of Western medicine and miracle healings can be a major obstacle to health education. Healthcare units with implemented or partially implemented prenatal care were compared in terms of their cost-effectiveness and perinatal results. : We determine the cost-effectiveness of a 2-stage emergency department intervention in addition to usual ED care compared with that of usual care alone. Finally, the variations of the retentions with the experimental conditions are shown to be quantitatively explained by a new model based on EEC.

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Cartilage lesions are very common causes of chronic knee pain in athletes. Mutation of a novel gene results in abnormal development of spermatid flagella, loss of intermale aggression and reduced body fat in mice. Since only 5 nL of the single cell reaction was removed, multiple sampling was possible, allowing triplicate analysis of enzyme activity cipro and alcohol for each individual cell. The electronic search was supplemented by scanning the reference lists of retrieved articles and contacting field experts. Combined magnetoresistance measurements and numerical simulations unambiguously relate the resistance oscillations to the penetration of vortex rows with intermediate geometrical pinning and uncover the details of geometrical melting. A technique is described whereby a wax or silicone index fixed partial denture is made at chairside, duplicating the temporary restoration that is directly transferable to the working casts of the articulator.

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Injury to podocytes leads to proteinuria, a hallmark of most glomerular diseases. It confirms the experimentally determined kinetic behavior of uncompetitive inhibition against either the inhibitor or the coenzyme. Influence of temperature on glutamate catabolism and glycogen production by organisms of the genus Chlamydia. The fat pad was dissected into five standardized segments, fixed in formalin and embedded in paraffin. Prospective surveillance methods that had been established within the hospital were not useful in identifying the number of involved individuals. Hopping diffusion of two coupled particles in the random trap model. In combination of utilizing a zithromax dosage chlamydia leader specific primer and primers complementary to porcine reproductive and respiratory syndrome virus (PRRSV) genome through RT-PCR, the leader junction sequences of subgenomic mRNA (sg mRNA) was identified from a Taiwanese isolate of PRRSV.

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With the advent of transgenic technology, novel animal models are being developed to facilitate prostate cancer research. This effect, often characterized by a reflected sound pattern consisting of two anti-phase beams, is due to the re-radiation of sound because of the stimulation of leaky Rayleigh waves. The independent variables are birthplace, ethnicity, and exposure to United States culture of Mexican and non Mexican adolescents. This unculturable pathogen has undergone extensive reductive evolution, with half of its genome now occupied by pseudogenes. Developmental changes in HIF transcription factor in carotid body: relevance for O2 sensing by chemoreceptors. To compare antigen-specific IgE titers and T-cell responses to JC pollen-derived extract and peptides in cohorts with high and low pollen exposure. Hemangiopericytoma from external auditory canal and middle ear: one case report.

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The phase mixing properties of model membranes consisting of mixtures of two or more synthetic or natural phospholipids are considered next. To concerned about chronic obstructive pulmonary disease and obstructive sleep apnea. 4CMB was directly active in all strains, inducing both frameshift and base-substitution mutations in a dose-dependent manner. A 2-month biliary stenting reduces stone size and number of stones. Seventy-nine specimens of atherosclerotic plaque removed from carotid or femoral arteries during surgery were immediately transferred to reduced transport fluid and brought to the laboratory. Mice fed nOVA or dOVA had identical tolerance of systemic DTH to levaquin pill color both forms of OVA, and feeding nOVA induced splenic Ts which suppressed the DTH response to both nOVA and dOVA. Nonetheless, the majority considered their birth records useful and important. This study compared colonoscopy, sigmoidoscopy and FOBT for colorectal cancer screening in asymptomatic adults.

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For the application of optical data storage, theories that we present can be used to design a diffractive super-resolution element (DSE) with the highest sidelobe suppressed. trachomatis LPS-induced apoptosis of sperm could be blocked with a pan-caspase inhibitor and a caspase-3 inhibitor. New progress has been made in cleaning up pollution, especially in the Huaihe River. Psychrophilic anaerobic digestion of guinea pig manure in low-cost tubular digesters at high altitude. Communication: Homocysteine, Thioretinaco Ozonide, Oxidative Phosphorylation, Biosynthesis of Phosphoadenosine Phosphosulfate and the Pathogenesis of Atherosclerosis. DNA diagnostics to identify internal feeders (Lepidoptera: Tortricidae) of pome fruits of quarantine importance.

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