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Aczone (Dapoxetine)
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Aczone

Aczone is a medication used for the treatment of premature ejaculation in men 18–64 years old. Aczone works by inhibiting the serotonin transporter, increasing serotonin's action at the postsynaptic cleft, and as a consequence promoting ejaculatory delay.

Other names for this medication:
Aczone, Dapoxetin, Dapoxetina, Dapoxetine, Dapoxetinum, Dapsone, Everlast

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Also known as: Dapoxetine

Description

Aczone was specifically developed to treat PE and is considered to be more effective in the treatment of PE than other drugs of the same class. Premature ejaculation is a male sexual dysfunction where a man ejaculates too quickly during sexual intercourse. Men with PE ejaculate in the same way as other men but it happens more quickly. Men with PE are not able to control their own ejaculation properly. The active ingredient of the medication is Dapoxetine, a selective serotonin reuptake inhibitor or SSRI which increases the time it takes to ejaculate. The average duration of the action of Aczone pill is 8-12 hours depending on the individual peculiarities of the male body.

Dosage

Take Aczone orally, one to three hours before sex. Aczone can be taken with or without food. It is recommended to start with the lower dose of 30mg for an initial 4 week period. Do not take more than one pill in a 24 hour period. Aczone is not recommended for daily use. Aczone is only recommended for men between 18-64 years of age.

Overdose

In case of a Aczone overdose visit your doctor or health care provider immediately. Symptoms of a Lasix overdose include fainting, tinnitus, confusion, weakness, lightheadedness, lack of appetite.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aczone are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Aczone if you are allergic to Dapoxetine or any of the other ingredients of this medication. Do not take Aczone if you have heart problems, e.g., heart failure or problems with the rhythm of your heart. Do not take Aczone if you have a history of fainting, mania (feeling over−excited, irritable or not being able to think clearly) or severe depression. Do not take Aczone if you have liver problems. Do not take Aczone if you are taking medication for depression. Do not take Aczone if you are taking medication for fungal infection, (ketoconazole and itraconazole), medication for HIV (ritonavir, saquinavir, nelfinavir and atazanavir), certain antibiotics for treating infection (telithromycin) or Nefazodone (an antidepressant). Aczone is not for use in children or adolescents under the age of 18 years. Avoid consuming alcohol while taking Aczone.

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RNA G-quadruplexes and their potential regulatory roles in translation. Preoperative neutrophil-to-lymphocyte ratio and tumor-related factors to predict lymph node metastasis in patients with pancreatic ductal adenocarcinoma (PDAC). To quantify the density, distribution, and depth of invasion of cysts in the corneas of eyes with acanthamoeba keratitis (AK) by in vivo confocal microscopy (IVCM) with a novel scanning pattern. Laparoscopic ischemic conditioning of the stomach increases neovascularization of the gastric conduit in patients undergoing esophagectomy for cancer. Objectives of this study were to (1) characterize the frequency and types of DRPs experienced by patients discharged on OPAT and (2) determine the fraction of adverse drug reactions (ADRs) resulting in hospital readmission or emergency department (ED) presentation and changes in therapy.

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