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Actical (Calcitriol)

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Actical is the active form of vitamin D, normally made in the kidney. It is also known as 1,25-dihydroxycholecalciferol. It is a hormone which binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes.

Other names for this medication:
Admax, Alfabond, Alfacalcirol, Alfacip, Alfarich, Arachitol, Biocitral, Calasto, Calbec, Calbory, Calbovic, Calcigra, Calcikind, Calcimet, Calcirol, Calcit, Calcor, Calday, Caldikind, Caldix, Calfa, Calgel, Calotec, Calsonic, Caltive, Calzem, Carcal, Citroj, Coecoral, Dmcal, Duracal, Ikmag, Koncal, Minroset, Netxod, Novadee, Osteobel, Primacal, Qpcal, Rical, Riecal, Ritoca, Rockbon, Roical, Romical, Solbiocal, Sunmic, Trolec, Vezocal, Zaxial

Similar Products:
Anafranil, Prograf, Cozaar, Geodon, Elocon, Imuran

Also known as: Calcitriol


Generic Actical is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Actical are intestine and bone. Generic Actical receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Actical may also act on the kidney and the parathyroid glands. Generic Actical is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Actical has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Actical, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Actical in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Actical produces other independent beneficial effects. Actical is also known as Calcitriol. Generic Actical treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Actical is Calcitriol. Brand name of Generic Actical is Actical.


Generic Actical is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Actical suddenly.


If you overdose Generic Actical and you don't feel good you should visit your doctor or health care provider immediately.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Actical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Evaluation of age and location of tumor are critical for its prognosis. Paediatric innovation in Pakistan: our experience and a call to action. Concentration-dependent effects of waterborne zinc on population dynamics of Gyrodactylus turnbulli (Monogenea) on isolated guppies ( Poecilia reticulata ). We would like to call for more case reports with postoperative neurological deficits as they present difficult clinical cases. Indications for osteosynthesis of facial bones with miniaturized plates. Evidence is presented that neuroblastoma tumor cells in host bone marrow is susceptible to autologous lymphokine-activated killer cells (LAK). New indications for established drugs: combined tumor-stroma-targeted cancer therapy with PPARgamma agonists, COX-2 inhibitors, mTOR antagonists and metronomic chemotherapy. Several studies on molecular mechanisms underlying death of erythrocytes have been reported. Impact of Heterogeneity in Sexual Behavior on Effectiveness in Reducing HIV Transmission with Test-and-Treat Strategy.

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Diagnosis and prevention, particularly secondary prophylaxis, will become even more important as increased urbanization, with greater population pressure and economic problems, increase the prevalence. Outcome of 89 psychiatric emergencies managed by 3 mental health centers in an emergency service. CHROMOSOME CONSTITUTION OF DIPLOID AND PSEUDODIPLOID CELLS IN EFFUSIONS OF CANCER PATIENTS. Haemorrhage into a cavernoma after traumatic head injury in a child. The plant hormone auxin is central in the regulation of growth and development, however, the molecular basis for its action has remained enigmatic. Our aim is to evaluate the correlation between BRCA mutational status and disease presentation in a large series of advanced high-grade serous ovarian cancer patients. In all, 57 species belonging to 19 families under 6 orders were found in the local water bodies. Based on the methods used in this study, we conclude that (1) the temporalis muscle develops from embryonic fibers that initially contain a myosin indistinguishable from embryonic limb muscle fibers, suggesting they have a common precursor, and (2) the myosin light chains and heavy chain unique to the temporalis muscle are initially expressed 2 weeks postpartum.

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Collectively, our results indicate that bFGF signaling plays indispensable roles in BMSC recruitment and transdifferentiation into CAFs and the consequent protumor effects, and targeting tumor stroma through bFGF inhibition maybe a promising strategy to suppress tumor progression. We analyzed retrospective data on the polarity of first mood episode obtained from 704 bipolar I subjects entering the multicenter Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study. Analytic and Clinical Validation of an Ultrasensitive, Quantitative Polymerase Chain Reaction Assay for EGFR Mutation Analysis With Circulating Tumor DNA. The assay reports an IC50 of 35.6 nM, reaching a limit of detection of 2.7 nM. Distracting driving is considered a dangerous epidemic in teenage drivers and adult drivers nationwide. Unfortunately, he could not take a spironolactone because of side effects. We demonstrate that several amino acid motifs conserved among ComFA proteins are important for efficient transformation. Furthermore, we explain the chronology of previously described whole-genome duplication events in the evolution of flowering plants. Prior to 1980, all patients had traditional excision, which was followed by a high incidence of complications and undesired sequelae, not the least of which was that the results of this aesthetic operation were often unaesthetic.

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Four cdc7 alleles have been tested for their effects on the u.v.-induced reversion of arg4-17, a highly u.v.-revertible ochre mutant. Solid state 29silicon nuclear magnetic resonance spectroscopy provided some insight concerning the interaction of the mobile phase additive with the silica-based stationary phase. This paper addresses the problem of recognizing human actions from RGB-D videos. We have established spontaneously immortalized Schwann cell lines from dorsal root ganglia and peripheral nerves of Sandhoff mice. Intraventricular hemorrhage requiring ventriculostomy placement is a frequent complication of spontaneous intracerebral hemorrhage. The purpose of this paper is to discuss the challenges of the grounded theory approach and the problems encountered by a researcher using the method for the first time. Laser Photoacoustic Detection of High Overtone Transitions of ClCN in the Near Infrared. Working wives experienced more confidence in coping than non-working wives.

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The DASH Diet, Sodium Intake and Blood Pressure Trial (DASH-Sodium) is a multicenter, randomized trial comparing the effects of 3 levels of sodium intake and 2 dietary patterns on blood pressure among adults with higher than optimal blood pressure or with stage 1 hypertension (120-159/80-95 mm Hg). Our results thus show that successive range expansion can promote intermixing over the short term and increase genetic diversity over the long term. Pharmacokinetics were studied for at least 6 days in patients and 5 days in mice. Mononuclear phagocytes are the most common cells in the kidney associated with immunity and inflammation. The role of drugs in the long-term management of cardiac arrhythmias. The toxic level of drugs on host cells was determined by colorimetric Methyl Tetrazolium (MTT) assay prior to activity tests.

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Pharmacokinetics of tissue-type plasminogen activator during acute myocardial infarction in men. Entorhinal cortex (EC) relays information from the hippocampus to the cerebral cortex. Biological Activities of Asteraceae (Achillea millefolium and Calendula officinalis) and Lamiaceae (Melissa officinalis and Origanum majorana) Plant Extracts. The addition of the iodinated contrast media helps to further demarcate its parenchymal lesions. Signalling in plant embryos during the establishment of the polar axis. LASP1, upregulated in HCC tissues and cell lines, was then identified as a novel target of miR-133b in HCC HepG2 and Hep3B cells. P-selectin, a granule membrane protein of platelets and endothelial cells, follows the regulated secretory pathway in AtT-20 cells. We have taken advantage of the fact that Purkinje cells do not express GAP-43 or L1 in adult mammals or regenerate axons into peripheral nerve grafts to test the importance of these molecules for axonal regeneration in vivo. Reversion of L-lysine inhibition of penicillin G biosynthesis by 6-oxopiperidine-2-carboxylic acid in Penicillium chrysogenum PQ-96. Multiple methods for risk stratification are available with the revised International Prognostic Scoring System (IPSS-R), currently considered the gold standard.

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Since the system was introduced with regulatory approval as a commercial product, clinicians were not bound by the constraints of a study protocol and only minimal data were collected. Urodynamic changes after tension-free sling procedures: Mycromesh-Plus vs TVT sling. Preventive Services Task Force recommends lung cancer screening with low-dose computed tomography for long-term current and former smokers. PROPOSED MAGNETIC AND ALLIED OBSERVATIONS DURING THE TOTAL SOLAR ECLIPSE OF JUNE 8, 1918. Milk ejection is a critical physiological process for successful lactation in humans and without glucotrol xl 5 mg it little milk can be removed. Larger methadone doses also completely blocked the subjective effects of heroin and produced greater withdrawal suppression during the outpatient periods.

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In certain cases, overexpression of HSP is rather toxic to the cells. monocytogenes a 4-kb operon, bvrABC, encoding an antiterminator of the BglG family (bvrA), a beta-glucoside-specific enzyme II permease component of the phosphoenolpyruvate-sugar phosphotransferase system (bvrB), and a putative ADP-ribosylglycohydrolase (bvrC). The previous urine osmolarity and serum creatinine levels were normal and the autopsy showed ATN. Patient-reported outcome measures were compared before and after surgery in eight studies. The action of these potent growth mediators is known to be regulated by adsorption to heparan sulfate proteoglycans (HSPGs) on the surface and within the extracellular matrix of other neighboring cells, which respectively promote or restrict interactions with their signal-transducing receptors on target cells. Tourniquets are routinely and safely used in limb surgeries throughout the world. Bach1-/- newborn mice were well-recovered from hyperoxia-induced lung injury. Finally, in a modeling study, we assessed the importance of co-feeding on R0, the basic reproductive number. We hierarchically assessed lot-to-lot consistency of 3 Hib-TT lots and non-inferiority of Hib-TT to Hib-TT control. Under these study conditions, treatment of partial-thickness burns with OCA spray resulted in a higher percent of re-epithelialization at seven but not 14 days when compared with both SSD and control, with no significant increase in infection rates.

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Convergence of visual and whisker responses in the primary somatosensory thalamus (ventral posterior medial region) of the mouse. The combination of phototherapy and chemotherapy (chemophototherapy, CPT), when carefully planned, has been shown to be an effective tumor treatment option preclinically and clinically. Mid-term clinical results and patient satisfaction after uterine artery embolization in women with symptomatic uterine fibroids. Safety and efficacy of pregabalin in adolescents with fibromyalgia: a randomized, double-blind, placebo-controlled trial and a 6-month open-label extension study. Interestingly, the level of active DAI was found to be low when cells were maintained under conditions nonpermissive for differentiation.

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ETV6/RUNX1 fusion gene using whole-exome sequencing. Neurochemical remodelling of the hippocampus in human temporal lobe epilepsy. A TECHNIC FOR DESTROYING THE PITUITARY WITH THE USE OF YTTRIUM -90 IN THE LIGHT OF OUR EXPERIENCES. The portal drained viscera glutamine release during severe hyperammonemia could be due to intestinal damage. Cytotoxic drug treatment of reactive amyloidosis in rheumatoid arthritis with special reference to renal insufficiency. The Multimedia Activity Recall for Children and Adults (MARCA), a computer-assisted telephone interview, measured use of time. There was no correlation between the clinical diagnosis of tonsillar disease and the presence of actinomycosis both in adult and pediatric patients. During severe influenza pneumonia and HPAI infection, the number of neutrophils in the lower respiratory tract is correlated with disease severity. On the other hand, in the washed caput and cauda regions, corticosterone induced a significant increase in total lipid, glyceride, and the mono, di, and triglyceride fractions, leaving total phospholipid and its fractions unaltered.

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